Effects of wild blueberries on heart, brain, and gut health in adults with high blood pressure

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of freeze-dried wild blueberries on cardiovascular health, cognitive function, and gut microbiota in non-Hispanic Black and White adults aged 45-65 with elevated blood pressure. Participants will be randomly assigned to receive either wild blueberries or a placebo for a specified duration. The study will assess various health parameters, including blood pressure, memory, and gut health, to determine the potential benefits of blueberry consumption. This research addresses a significant gap in understanding the impact of dietary interventions on hypertension and related health outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Individuals 45-65 years of age
* Diagnosis of elevated blood pressure or stage 1 hypertension (systolic blood pressure = 120-139 mmHg and/or diastolic blood pressure = 80-89 mmHg) for at least 6 months
* BMI 25-35 kg/m2 via anthropometric measurements.
* Ability to give consent

Exclusion Criteria:

* Allergies to berries
* Use of one hypertensive drug for less than three months
* Use of more than one anti-hypertensive or statin drug, insulin, antibiotics, and anti-inflammatory drugs, active cancer, gastrointestinal, renal, cardiovascular, thyroid, and neurological disorders or severe head injury
* Smoking
* Alcohol consumption (\>2 drinks/day)
* Consuming antioxidant, probiotic, and prebiotic supplements
* Pregnant or lactating
* Participating in a weight loss program

Where it's running

• Georgia State University
  Atlanta, Georgia, United States Recruiting

Study contacts

• Principal investigator: Rafaela G Feresin, PhD — Georgia State University
• Study coordinator: Rafaela G Feresin, PhD
• Email: berries@gsu.edu
• Phone: 404-413-1233

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.