Evaluating ECMO therapy timing for children with septic shock

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness and optimal timing of Extracorporeal Membrane Oxygenation (ECMO) therapy in children suffering from refractory septic shock. It employs a multi-center, prospective, non-randomized controlled design to analyze various clinical indicators that may influence ECMO treatment outcomes. The research aims to develop a prediction model to determine the best timing for ECMO intervention, assessing factors such as ScVO2, lactic acid levels, and vasoactive inotrope scores. The ultimate goal is to enhance the clinical application of ECMO in pediatric sepsis management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

• Children with septic shock and refractory septic shock admitted to the PICU of all the study centers

Exclusion Criteria:

* Fatal chromosomal abnormalities (e.g., trisomy 13 or 18)
* Uncontrolled bleeding
* Irreversible brain damage
* After allogeneic bone marrow transplantation
* Weight less than 2.5kg or severe malnutrition

Where it's running

• Children'S Hosptial of Fuan University
  Shanghai, China Recruiting

Study contacts

• Principal investigator: Guoping Lu, Doctor — Children's Hospital of Fudan University
• Study coordinator: Guoping Lu, Doctor
• Email: 13788904150@163.com
• Phone: +8613788904150

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.