Condition

Dyspepsia clinical trials and research

• 12Clinical trials
• 6NIH research projects
• 11Countries

Newest Dyspepsia clinical trials

All recruiting trials (12)

• Virtual poetry workshops to boost well-being for people with digestive symptoms

  This study tests whether participating in online poetry workshops can improve emotional well-being for adults with chronic digestive symptoms and anxiety or depression.

  Recruiting Ohio State University · Columbus, Ohio · NCT07717541

• Symptoms and quality of life in people with gastric inlet patches

  This study will see if adults having a medically indicated gastroscopy who have heterotopic gastric mucosa (gastric inlet patches) are more likely to have swallowing problems, indigestion, or lower quality of life than those without it.

  Recruiting Knappschaft Kliniken GmbH · Bottrop, North Rhine-Westphalia · NCT07510984

• Carbon footprint of diagnostic versus therapeutic upper GI endoscopy

  This project will measure how much carbon is produced by diagnostic endoscopy for dyspepsia compared with therapeutic endoscopy for non-variceal upper GI bleeding.

  Recruiting at 2 sites King Chulalongkorn Memorial Hospital · Bangkok and 1 other locations · NCT07261228

• Adding Saccharomyces boulardii to bismuth quadruple therapy for H. pylori rescue

  This tests whether adding the probiotic Saccharomyces boulardii to bismuth-containing quadruple therapy helps adults whose H. pylori infection did not clear after prior treatments.

  Recruiting Phase 4 Xijing Hospital of Digestive Diseases · Xi'an, Shaanxi · NCT07139366

• High-resolution stomach mapping with gastroduodenal pressure testing

  This study tests whether high-resolution body-surface gastric mapping and gastroduodenal manometry, with or without transcutaneous vagal nerve stimulation (tVNS), can identify stomach dysfunction patterns that match symptoms in people with functional dyspepsia.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT06941545

• Chios mastic water for dyspepsia

  This 3-month randomized, double-blind test will see if adults aged 30–60 with dyspepsia feel better when they drink 600 mL per day of a carbonated beverage containing Chios mastic water versus a placebo beverage.

  Recruiting Harokopio University · Kallithea, Attica · NCT06909890

• Evaluating the effectiveness of Danning Tablets for digestive symptoms

  This study is testing if Danning Tablets can help people aged 18 to 75 feel better from digestive issues like indigestion and bloating while they are already using the medication.

  Recruiting Shanghai Hutchison Pharmaceuticals Limited · Hangzhou, Zhejiang · NCT06755671

• Investigating the effects of treating Helicobacter Pylori on dyspepsia symptoms

  This study is testing if treating Helicobacter pylori can help people with upset stomach symptoms feel better over time.

  Recruiting at 26 sites Shanghai Jiao Tong University School of Medicine · Chongqing, Chongqing Municipality and 25 other locations · NCT06422052

• Video-guided training to reduce visible abdominal bloating

  This project tries a simple video-guided biofeedback program versus a sham program to see if it reduces visible belly swelling after meals in people with IBS, dyspepsia, or functional bloating.

  Recruiting at 2 sites Hospital Universitari Vall d'Hebron Research Institute · Los Angeles, California and 6 other locations · NCT06369753

• Comparing famotidine and antacids for treating dyspepsia

  This study is testing whether an IV medication called famotidine works better than an antacid for quickly relieving stomach pain in people with dyspepsia who come to the emergency room.

  Recruiting Phase 4 Stony Brook University · Stony Brook, New York · NCT06241183

• Cognitive Behavioral Therapy for Food Intake Issues in Dyspepsia

  This study is testing whether a special kind of therapy delivered online can help adults with functional dyspepsia and food intake issues feel better and improve their eating habits.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT05587127

• Observing functional digestive disorders

  This study is collecting health information and samples from people with digestive issues like irritable bowel syndrome to see if it can help find better treatments for them.

  Recruiting University Hospital, Rouen · Rouen · NCT04918329

NIH-funded research (6)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Vagus nerve stimulation plus cognitive behavioral therapy to ease functional dyspepsia symptoms

  This project combines gentle vagus nerve stimulation with cognitive behavioral therapy to help adults with functional dyspepsia reduce stomach pain, fullness, and related anxiety.

  NIH research Spaulding Rehabilitation Hospital · Charlestown, United States · NIH-11327318

• How different body areas affect the brain-gut connection in people with indigestion

  This research explores how stimulating specific body points might improve digestion and brain-gut communication for people experiencing chronic indigestion.

  NIH research Spaulding Rehabilitation Hospital · Charlestown, United States · NIH-11128820

• Exploring the effects of vagal stimulation and therapy on gut-brain interactions in functional dyspepsia

  This study is looking at whether using a device that stimulates the vagus nerve along with talking therapy can help people with functional dyspepsia feel better and improve their quality of life.

  NIH research Spaulding Rehabilitation Hospital · Charlestown, United States · NIH-11095974

• Understanding eating problems in adults with functional dyspepsia

  This study is looking at the eating challenges faced by adults with functional dyspepsia to understand what makes it hard for them to eat and to test a new program that could help them enjoy a wider variety of foods again.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-10917137

• Investigating how different acupuncture points affect the gut-brain connection in functional dyspepsia.

  This study is looking at how acupuncture might help people with functional dyspepsia by seeing how it affects the brain and stomach, using special imaging techniques to track any changes during treatment.

  NIH research Spaulding Rehabilitation Hospital · Charlestown, United States · NIH-10881998

• Investigating a new treatment for functional dyspepsia

  This study is looking at how a new medication called tradipitant can help people with functional dyspepsia, which causes ongoing stomach pain and discomfort, by checking how well it works and how safe it is compared to other treatments.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-10798325

Related topics

Quick answers

How many Dyspepsia clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in United States (5 trials), China (3 trials), France (2 trials), Canada (1 trial), Italy (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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