Understanding eating problems in adults with functional dyspepsia
Official title: A Biobehavioral Approach to Understand Problematic Avoidant/Restrictive Eating in Adults with Functional Dyspepsia
Funded at Massachusetts General Hospital · NIH-10917137 · Data updated 2026-11-12
This study is looking at the eating challenges faced by adults with functional dyspepsia to understand what makes it hard for them to eat and to test a new program that could help them enjoy a wider variety of foods again.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 13, 2021 |
| Project end | September 28, 2026 |
| Funding year | 2024 |
| Award (this year) | $199,472 |
| NIH project number | 5K23DK131334-04 |
| Project ID | NIH-10917137 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old who have been diagnosed with functional dyspepsia and exhibit avoidant/restrictive eating behaviors.
✕Less likely to help
Patients who do not have functional dyspepsia or those whose eating issues are unrelated to this condition may not benefit from this research.
What this research studies
This research investigates the eating difficulties faced by adults with functional dyspepsia, a chronic gastrointestinal disorder. It aims to explore the biological and behavioral factors that contribute to avoidant/restrictive eating patterns in these patients. By comparing gastric functions and hormone levels among those with functional dyspepsia and avoidant/restrictive food intake disorder (ARFID), healthy individuals, and those with functional dyspepsia without ARFID, the study seeks to identify potential treatment targets. Additionally, it will pilot a cognitive-behavioral intervention designed to help patients gradually increase their food intake and variety, addressing both the psychological and physiological aspects of their eating challenges.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for adults struggling with eating issues related to functional dyspepsia.
How similar studies have gone: While the specific approach of this research is novel, similar studies have shown promise in addressing eating disorders through behavioral interventions.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Burton Murray, Helen — Massachusetts General Hospital
- Study coordinator: Burton Murray, Helen
Related research
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-
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Exploring the effects of vagal stimulation and therapy on gut-brain interactions in functional dyspepsia
This study is looking at whether using a device that stimulates the vagus nerve along with talking therapy can help people with functional dyspepsia feel better and improve their quality of life.
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Investigating how different acupuncture points affect the gut-brain connection in functional dyspepsia.
This study is looking at how acupuncture might help people with functional dyspepsia by seeing how it affects the brain and stomach, using special imaging techniques to track any changes during treatment.
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Investigating a new treatment for functional dyspepsia
This study is looking at how a new medication called tradipitant can help people with functional dyspepsia, which causes ongoing stomach pain and discomfort, by checking how well it works and how safe it is compared to other treatments.
-
Evaluating the effectiveness of Danning Tablets for digestive symptoms
This study is testing if Danning Tablets can help people aged 18 to 75 feel better from digestive issues like indigestion and bloating while they are already using the medication.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.