Condition

Functional Dyspepsia clinical trials and research

• 30Clinical trials
• 6NIH research projects
• 1New in 30 days
• 15Countries

Newest Functional Dyspepsia clinical trials

All recruiting trials (30)

• Low-FODMAP Diet vs Standard Dietary Advice for Functional Dyspepsia

  This study tests whether a low-FODMAP diet helps adults with functional dyspepsia compared with standard dietary advice.

  Recruiting King Chulalongkorn Memorial Hospital · Bangkok, Pathumwan · NCT07925073

• Pain Reprocessing Therapy for Functional Dyspepsia

  A small pilot test to see if a psychological therapy that uses exposure techniques can lessen digestive symptoms and help daily functioning in people with functional dyspepsia.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07838324

• Identifying Signatures of Gut Interoception in Functional Dyspepsia and Anorexia Nervosa

  This study tests how the gut-brain connection works in people with functional dyspepsia or anorexia nervosa using brain imaging.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT07772167

• Prevalence and possible role of non-H. pylori Helicobacter species in gastric conditions and cancers

  Researchers will test stomach tissue from people with functional dyspeasia, various gastritis conditions, gastric cancer, and bariatric patients to see if non-H. pylori Helicobacter species are present.

  Recruiting at 3 sites Universiteit Antwerpen · Edegem and 2 other locations · NCT07770126

• Liver Fat and Scarring in People Suspected of Non-Celiac Wheat Sensitivity

  This study looks to see if people with non-celiac wheat sensitivity have liver fat or fibrosis and how this relates to IBS/FD and celiac disease.

  Recruiting at 2 sites University of Palermo · Palermo, Palermo and 1 other locations · NCT07750535

• Prevalence of Functional Dyspepsia in a Rural Community in Bangladesh

  This study tests how common functional dyspepsia is in a rural Bangladeshi community among adults who live there.

  Recruiting Bangladesh Medical University · Dhaka · NCT07694778

• DA-9701 in functional dyspepsia: see if it helps reduce symptoms

  This study tests whether DA-9701 (and related formulations) can help adults with functional dyspepsia feel better compared with placebo.

  Recruiting Phase 4 Dong-A ST Co., Ltd. · Seoul · NCT07686679

• Wheat sensitivity or IBS/functional dyspepsia in relatives of people with celiac disease

  This project will test whether adults related to celiac patients have higher rates of non-celiac wheat sensitivity or IBS/functional dyspepsia and whether symptoms change on a wheat-free diet.

  Recruiting at 2 sites University of Palermo · Palermo, PA and 1 other locations · NCT07584473

• Ear acupressure for functional dyspepsia with insomnia

  This trial will test whether pressing specific points on the ear can reduce bothersome upper‑abdominal dyspepsia symptoms and improve sleep in adults with functional dyspepsia and insomnia.

  Recruiting The First Affiliated Hospital of Zhejiang Chinese Medical University · Hangzhou, Zhejiang · NCT07442734

• Internet-delivered gut-directed hypnotherapy versus iCBT for stomach pain in children and teens

  This trial will test whether online gut-directed hypnotherapy or internet-based cognitive behavioral therapy helps children and adolescents (8–17) with IBS, functional abdominal pain, or functional dyspepsia reduce stomach pain and improve daily life.

  Recruiting Karolinska Institutet · Stockholm · NCT07319078

• Comparing symptoms in atrophic gastritis and dyspepsia

  This project will test whether people with pathologically confirmed chronic atrophic gastritis have different types or severity of dyspepsia symptoms than similar patients without atrophic gastritis.

  Recruiting The Third Affiliated hospital of Zhejiang Chinese Medical University · Hangzhou, Zhejiang · NCT07250308

• Guided imagery therapy app for kids with functional abdominal pain

  This study tests a guided imagery therapy app to see if it helps school-age children with functional abdominal pain disorders.

  Recruiting at 2 sites Baylor College of Medicine · Austin, Texas and 1 other locations · NCT07222943

• Probiotic and ginger supplement for symptoms and quality of life in functional dyspepsia

  This study will test whether a daily Symbiosys Stomalex supplement (Bacillus coagulans MY01, Bacillus subtilis MY02 and ginger) can reduce symptoms and improve quality of life in adults with functional dyspepsia.

  Recruiting at 2 sites Biocodex · Rouen, Boulevard Gambetta and 1 other locations · NCT07212907

• Press-needle acupuncture on body and ear points for functional dyspepsia

  This study tests whether adding press-needle acupuncture on body and ear points to usual medication helps adults with functional dyspepsia have fewer symptoms and better quality of life.

  Recruiting Universitas Indonesia · Jakarta Pusat, DKI Jakarta · NCT07210294

• Bioelectrical impedance comparison of body composition in women with functional dyspepsia and healthy women

  This project will use a quick, noninvasive bioelectrical impedance scan to see if women with functional dyspepsia have different fat mass, fat‑free mass, or phase angle compared with healthy women.

  Recruiting Universitair Ziekenhuis Brussel · Brussels · NCT07196735

• Clostridium butyricum for anxiety and depression in functional dyspepsia

  This trial will test whether taking the probiotic Clostridium butyricum for four weeks can reduce anxiety and depression symptoms in adults with functional dyspepsia.

  Recruiting Phase 4 Xijing Hospital of Digestive Diseases · Xi’an, Shanxi · NCT07182890

• Amitriptyline versus Trifluoperazine for functional dyspepsia

  This trial will test whether adding low‑dose amitriptyline or trifluoperazine to standard treatment helps adults with functional dyspepsia feel better over 8 weeks.

  Recruiting Phase 2/3 Dhaka Medical College · Dhaka · NCT07008235

• How different FODMAP diets affect people with IBS and functional dyspepsia

  This test will try low FODMAP, gentle FODMAP, and standard dietary advice in adults with IBS or functional dyspepsia to see how they change symptoms, gut bacteria, gut barrier function, and quality of life.

  Recruiting Universiti Kebangsaan Malaysia Medical Centre · Kuala Lumpur, Kuala Lumpur · NCT07000227

• Personalized neurostimulation for children with gastrointestinal disorders

  This study is testing a new treatment that combines personalized nerve stimulation and hypnotherapy to see if it can help children with stomach problems feel better.

  Recruiting Medical College of Wisconsin · Milwaukee, Wisconsin · NCT06863207

• Prokinetics and Body Surface Gastric Mapping in Dyspeptic Patients

  This study tests whether using Body Surface Gastric Mapping can help predict which medications will help people with gastroparesis or functional dyspepsia see improvement.

  Recruiting at 2 sites University of Auckland, New Zealand · Philadelphia, Pennsylvania and 2 other locations · NCT06854120

• Budesonide treatment for functional dyspepsia

  This study is testing if Budesonide can help people with functional dyspepsia feel better by reducing inflammation in their digestive system.

  Recruiting Phase 4 Universitaire Ziekenhuizen KU Leuven · Leuven · NCT06841406

• Cognitive Behavioral Therapy via Mobile App for Functional Dyspepsia

  This study tests if an 8-week mobile app program using cognitive behavioral therapy can help adults with stubborn stomach issues feel better, compared to traditional medications.

  Recruiting at 5 sites Air Force Military Medical University, China · Haikou, Hainan and 6 other locations · NCT06756139

• Evaluating the effectiveness of Danning Tablets for digestive symptoms

  This study is testing if Danning Tablets can help people aged 18 to 75 feel better from digestive issues like indigestion and bloating while they are already using the medication.

  Recruiting Shanghai Hutchison Pharmaceuticals Limited · Hangzhou, Zhejiang · NCT06755671

• Electroacupuncture to relieve functional dyspepsia symptoms

  This trial will test whether two electroacupuncture frequencies (5 Hz and 100 Hz) help adults aged 18–80 with functional dyspepsia feel better compared with a sham procedure.

  Recruiting at 4 sites The Third Affiliated hospital of Zhejiang Chinese Medical University · Hangzhou, None Selected and 3 other locations · NCT06618911

• Combining gentle ear vagus nerve stimulation with online support to ease functional dyspepsia

  This trial will test whether daily mild ear vagus nerve stimulation plus weekly online support sessions can help adults with functional dyspepsia reduce stomach pain and bothersome fullness.

  Recruiting Spaulding Rehabilitation Hospital · Boston, Massachusetts · NCT06360900

• Assessing gastric functions in patients with diabetes

  This study looks at how diabetes affects stomach function in people with Type 1 and Type 2 diabetes to see if there are any problems and how these issues relate to their overall health.

  Recruiting at 5 sites Institute for Clinical and Experimental Medicine · Ostrava and 4 other locations · NCT06068114

• Using virtual reality to treat functional dyspepsia symptoms

  This study is testing if virtual reality can help people with functional dyspepsia feel better by reducing their stomach symptoms.

  Recruiting Mayo Clinic · Jacksonville, Florida · NCT05836597

• Cognitive Behavioral Therapy for Food Intake Issues in Dyspepsia

  This study is testing whether a special kind of therapy delivered online can help adults with functional dyspepsia and food intake issues feel better and improve their eating habits.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT05587127

• Evaluating the effects of EDL on dyspepsia symptoms

  This study is testing whether a natural extract called EDL can help adults with functional dyspepsia feel better compared to a placebo.

  Recruiting Seoul National University Bundang Hospital · Seongnam-si, Gyeonggi-do · NCT04482478

• Ketotifen treatment for children with functional dyspepsia and duodenal eosinophilia

  This study is testing if ketotifen can help children aged 8 to 17 with stomach issues and high eosinophils feel better when other treatments haven't worked.

  Recruiting Phase 3 Children's Mercy Hospital Kansas City · Kansas City, Missouri · NCT02484248

NIH-funded research (6)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Vagus nerve stimulation plus cognitive behavioral therapy to ease functional dyspepsia symptoms

  This project combines gentle vagus nerve stimulation with cognitive behavioral therapy to help adults with functional dyspepsia reduce stomach pain, fullness, and related anxiety.

  NIH research Spaulding Rehabilitation Hospital · Charlestown, United States · NIH-11327318

• How different body areas affect the brain-gut connection in people with indigestion

  This research explores how stimulating specific body points might improve digestion and brain-gut communication for people experiencing chronic indigestion.

  NIH research Spaulding Rehabilitation Hospital · Charlestown, United States · NIH-11128820

• Exploring the effects of vagal stimulation and therapy on gut-brain interactions in functional dyspepsia

  This study is looking at whether using a device that stimulates the vagus nerve along with talking therapy can help people with functional dyspepsia feel better and improve their quality of life.

  NIH research Spaulding Rehabilitation Hospital · Charlestown, United States · NIH-11095974

• Understanding eating problems in adults with functional dyspepsia

  This study is looking at the eating challenges faced by adults with functional dyspepsia to understand what makes it hard for them to eat and to test a new program that could help them enjoy a wider variety of foods again.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-10917137

• Investigating how different acupuncture points affect the gut-brain connection in functional dyspepsia.

  This study is looking at how acupuncture might help people with functional dyspepsia by seeing how it affects the brain and stomach, using special imaging techniques to track any changes during treatment.

  NIH research Spaulding Rehabilitation Hospital · Charlestown, United States · NIH-10881998

• Investigating a new treatment for functional dyspepsia

  This study is looking at how a new medication called tradipitant can help people with functional dyspepsia, which causes ongoing stomach pain and discomfort, by checking how well it works and how safe it is compared to other treatments.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-10798325

Related topics

Quick answers

How many Functional Dyspepsia clinical trials are recruiting right now?

30, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 15 countries. The most sites are in United States (9 trials), China (6 trials), Belgium (3 trials), South Korea (2 trials), Bangladesh (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 3, Phase 2/3: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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