Comparing famotidine and antacids for treating dyspepsia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to compare the effectiveness of intravenous famotidine, an H2 receptor antagonist, with oral Maalox/Mylanta, an antacid, in treating dyspepsia symptoms in patients presenting to the emergency department. Approximately 80 patients will be randomized into two groups to receive either treatment, and their pain levels will be assessed using a verbal numeric pain scale at multiple time points after administration. The study seeks to determine which treatment provides faster and more significant relief from pain associated with dyspepsia.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Subject Age ≥ 18 years of age
2. Patient diagnosed with dyspepsia
3. Present at the ED with upper abdominal pain score of at least 3

Exclusion Criteria:

1. Hypersensitivity to an ingredient in Maalox/ Mylanta or Famotidine
2. Moderate to Severe Renal Insufficiency (precaution)
3. Kidney Failure
4. Pregnant or Nursing
5. Verbal pain score less than 3
6. Inability to tolerate oral medications
7. Bowel Obstruction
8. Proton pump inhibitor within 2 hours of study treatment

Where it's running

• Stony Brook University Hospital
  Stony Brook, New York, United States Recruiting

Study contacts

• Study coordinator: Adam Singer, MD
• Email: adam.singer@stonybrookmedicine.edu
• Phone: 6314447857

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.