Investigating the effects of treating Helicobacter Pylori on dyspepsia symptoms

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter, prospective, observational study aims to assess the incidence of dyspeptic symptoms in patients infected with Helicobacter pylori. It will follow patients over time to evaluate the remission of these symptoms after receiving eradication treatment for the infection. The study utilizes an epidemiological questionnaire and a Functional Dyspepsia Symptom Diary to gather data on patient experiences and outcomes. The findings are intended to inform clinical diagnosis and treatment strategies for those affected by H. pylori and dyspepsia.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male or female patients aged 18-80 years
* H. pylori infection diagnosed by 13C/ 14C-UBT (\> 2 times the cutoff value) and/or gastroscopy (rapid urease strong positive and histological positive)
* Treatment-naive patients with Helicobacter pylori
* Ability and willingness to participate in the study and to sign and give informed consent

Exclusion Criteria:

* Under 18 or over 80 years old
* Organic digestive diseases, such as active peptic ulcer, gastroesophageal reflux, gastrointestinal bleeding, acute/chronic pancreatitis, acute/chronic cholecystitis, gallstones, intestinal obstruction, inflammatory bowel disease, etc.
* Combined with melena, hematemesis, anemia, emaciation and other alarm symptoms
* Pregnant and lactating women
* History of cancer
* History of subtotal gastrectomy
* Severe organ dysfunction of heart, liver, kidney, lung and other important organs and congenital diseases, such as grade IV heart failure, liver failure, uremia, respiratory failure, hemophilia, Wilson's disease, etc.

Where it's running

• Chongqing Daping Hospital
  Chongqing, Chongqing Municipality, China Recruiting
• The Ninth People's Hospital of Chongqing
  Chongqing, Chongqing Municipality, China Recruiting
• The People's Hospital of Kaizhou District, CQ
  Chongqing, Chongqing Municipality, China Recruiting
• The First Affiliated Hospital of Xiamen University
  Xiamen, Fujian, China Recruiting
• The People's Hospital of Wuwei
  Wuwei, Gansu, China Recruiting
• The First People's Hospital of Qinzhou
  Qinzhou, Guangxi, China Recruiting

Study contacts

• Study coordinator: Hong Lu, MD
• Email: hlu@sjtu.edu.cn
• Phone: +8613611958022

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.