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Drug Overdose clinical trials and research
As of November 12, 2026, Find a Trial lists 6 Drug Overdose clinical trials that are recruiting, at sites in 8 countries (most in United States (4), France (1), Austria (1)). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 6Clinical trials
- 8Countries
Newest Drug Overdose clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| The ENHANCE Project Toolkit | — | Madison, Wisconsin | Recruiting | Jun 16, 2026 |
| BSAFE: Brief Intervention to Reduce Fentanyl Risk for stimulant users | — | San Francisco, California | Recruiting | Oct 21, 2025 |
| Recognizing dapagliflozin overdose in ICU patients admitted for metformin poisoning. | — | Saint-Denis, France | Recruiting | Sep 25, 2025 |
| Social intervention for overdose prevention and education | — | Baltimore, Maryland | Recruiting | Mar 25, 2024 |
| Peer-driven intervention to prevent HIV, HCV, and drug overdoses among people who inject drugs | — | Baltimore, Maryland | Recruiting | Apr 11, 2022 |
| Registry for monitoring CytoSorb device use in critically ill patients | — | Klagenfurt and 27 other locations | Recruiting | Dec 6, 2021 |
All recruiting trials (6)
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The ENHANCE Project Toolkit
This pilot study tests a bundle of smartphone and online tools to help people who use drugs reduce overdose risk.
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BSAFE: Brief Intervention to Reduce Fentanyl Risk for stimulant users
A randomized trial tests a repeated brief education program to see if it lowers overdose risk among adults who use cocaine or methamphetamine and may have unintentional fentanyl exposure.
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Recognizing dapagliflozin overdose in ICU patients admitted for metformin poisoning.
This project will see if clinical signs and routine lab tests can help doctors tell whether adults in the ICU for metformin poisoning also took too much dapagliflozin.
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Social intervention for overdose prevention and education
This study is trying out a program that teaches people who use opioids and their friends and family how to prevent and respond to drug overdoses.
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Peer-driven intervention to prevent HIV, HCV, and drug overdoses among people who inject drugs
This study is testing whether getting support and education from peers can help people who inject drugs reduce their risk of HIV, hepatitis C, and overdoses.
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Registry for monitoring CytoSorb device use in critically ill patients
This study is collecting information on how the CytoSorb device helps critically ill patients to improve care for conditions like septic shock and acute respiratory distress syndrome.
Related topics
Quick answers
How many Drug Overdose clinical trials are recruiting right now?
6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 8 countries. The most sites are in United States (4 trials), France (1 trial), Austria (1 trial), Germany (1 trial), Italy (1 trial). Each study page lists its sites and which ones are recruiting.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.