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Metformin clinical trials and research

• 8Clinical trials
• 4Countries

Newest Metformin clinical trials

All recruiting trials (8)

• Recognizing dapagliflozin overdose in ICU patients admitted for metformin poisoning.

  This project will see if clinical signs and routine lab tests can help doctors tell whether adults in the ICU for metformin poisoning also took too much dapagliflozin.

  Recruiting Centre Hospitalier de Saint-Denis · Saint-Denis, France · NCT07193069

• Beetroot juice to boost blood vessels, insulin sensitivity, and exercise in prediabetes on vs. off metformin

  In people with prediabetes, this study tests whether short-term inorganic nitrate from beetroot juice can improve blood vessel health, insulin sensitivity, and exercise capacity, and compares those already taking metformin with those who are not.

  Recruiting University of Virginia · Charlottesville, Virginia · NCT07131384

• Evaluating the effects of metformin on aging in older men

  This study is testing if the diabetes drug metformin can help older men slow down the aging process.

  Recruiting Phase 2 Xuanwu Hospital, Beijing · Beijing · NCT06459310

• Using Metformin to Improve Live Birth Rates in Women with Prediabetes Undergoing IVF

  This study is testing if taking metformin before IVF can help women with prediabetes have a healthier chance of getting pregnant and having a baby.

  Recruiting Shandong University · Jinan, Shandong · NCT06064669

• Metformin added to temozolomide for newly diagnosed IDH-wildtype glioblastoma

  This Phase 2 trial will test if adding metformin to standard temozolomide helps adults with newly diagnosed IDH-wildtype glioblastoma.

  Recruiting Phase 2 University of Milano Bicocca · Milan · NCT05929495

• Metformin to improve muscle strength in myotonic dystrophy type 1

  This will test whether taking metformin can improve muscle strength and daily function in adults with myotonic dystrophy type 1 who can still walk.

  Recruiting Phase 3 Assistance Publique - Hôpitaux de Paris · Garches · NCT05532813

• Comparing metformin addition to standard care after bariatric surgery for diabetes remission

  This study is testing if adding metformin to regular care can help adults who had weight loss surgery keep their diabetes in remission longer.

  Recruiting at 13 sites Phase 3 Assistance Publique - Hôpitaux de Paris · Amiens and 15 other locations · NCT04581447

• Using Metformin to Reduce Heart Risks in Veterans with Prediabetes

  This study tests if the diabetes drug metformin can help reduce the risk of heart attacks, strokes, and death in Veterans with prediabetes and heart disease.

  Recruiting at 37 sites Phase 4 VA Office of Research and Development · Phoenix, Arizona and 39 other locations · NCT02915198

Related topics

Quick answers

How many Metformin clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in France (3 trials), United States (2 trials), China (2 trials), Italy (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 3: 2, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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