Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Social intervention for overdose prevention and education

Official title: A Social Diffusion Fatal Overdose Prevention Intervention: Assessing the Effectiveness of People Who Use Opioids as Peer Educators in Training Using & Non-using Networks on Overdose & Stigma Reduction

Run by Johns Hopkins Bloomberg School of Public Health · NCT06327061 · Data updated 2026-11-12

This study is trying out a program that teaches people who use opioids and their friends and family how to prevent and respond to drug overdoses.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment600 (estimated)
SponsorJohns Hopkins Bloomberg School of Public Health
Academic / other
Locations1 site (Baltimore, Maryland)
StatusRecruiting
StartedJune 1, 2024
Main results expectedApril 30, 2028
Study endsApril 1, 2029
Registry record updatedMarch 4, 2026
Trial IDNCT06327061 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 18 and older who self-report illicit opioid use and live in the Baltimore metropolitan area.

Probably not a fit

Patients who do not use opioids or those who lack the cognitive ability to provide informed consent may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study tests a social intervention aimed at preventing drug overdoses by training both people who use opioids and their non-using network members. The intervention includes three sessions for opioid users to become peer educators and one session for non-using network members to learn about overdose response. The goal is to enhance the ability of social networks to respond to overdoses and foster discussions about overdose prevention. The study builds on previous findings that peer education can be effective in overdose prevention efforts.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce the incidence of drug overdoses by empowering both users and their support networks with the knowledge and skills to respond effectively.

How similar studies have gone: Previous studies have shown success with peer education approaches in overdose prevention, indicating potential for this intervention's effectiveness.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* self-reported illicit opioid use at least 2 times in the past two weeks;
* age 18 and older;
* living in the Baltimore metropolitan region;
* willing to engage in peer education; and
* having and willing to recruit at least one non-using network member.

Exclusion Criteria:

Participants without the cognitive ability to provide informed consent and have the physical ability to participate in in-person intervention sessions.

Where it's running

  • Johns Hopkins Bloomberg School of Public Health
    Baltimore, Maryland, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.