Recognizing dapagliflozin overdose in ICU patients admitted for metformin poisoning.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational comparison of adults admitted to a single ICU for acute metformin poisoning, separating patients exposed to metformin alone from those exposed to both metformin and dapagliflozin. Researchers will review clinical data and standard laboratory results—such as acid-base status, lactate, ketones, glucose, and need for dialysis or vasopressors—collected during ICU care. The team will look for patterns or distinct findings that appear more often when dapagliflozin is involved. Results aim to identify timely clues clinicians can use at the bedside to suspect combined overdose and guide management decisions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 years or older
* Admission to an intensive care unit (ICU) due to acute drug poisoning
* Documented exposure to either:
* Metformin alone
* Metformin in combination with dapagliflozin

Exclusion Criteria:

* Patients under 18 years of age
* No exposure to metformin
* Exposure to dapagliflozin without metformin

Where it's running

• Centre Hospitalier de Saint-Denis
  Saint-Denis, France, France Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.