Condition

Disability clinical trials and research

• 10Clinical trials
• 118NIH research projects
• 5Countries

Newest Disability clinical trials

All recruiting trials (10)

• Pain Neuroscience Education Added to Pre-Op Physical Therapy for Lumbar Surgery

  A randomized trial tests whether adding Pain Neuroscience Education to standard pre-operative physical therapy helps reduce pain and disability after lumbar laminectomy for people aged 35-60.

  Recruiting Foundation University Islamabad · Islamabad · NCT07801586

• Effects of Oculomotor Exercises for Non-Traumatic Cervical Dizziness

  This study tests whether adding oculomotor exercises to a neck exercise program helps people with chronic non-traumatic cervical dizziness.

  Recruiting Riphah International University · Faisalābad, Punjab Province · NCT07790874

• Lumbar Stability Exercises vs Telerehabilitation for postpartum back pain and posture

  This study tests whether onsite lumbar stabilization exercises or a telerehabilitation program can reduce the curved lower back (lumbar lordosis), pain, and disability in women 6 weeks to 12 months after giving birth.

  Recruiting Foundation University Islamabad · Islamabad, Punjab Province · NCT07593183

• Digital system to detect and prevent disability risk in older adults

  This project will test a smartphone-enabled system that looks for early signs of disability and offers tailored prevention and management for people aged 65 and older.

  Recruiting Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang · NCT07508813

• Minnesota RETAIN: a program to help people stay at or return to work after injury or illness

  This project will try expanding the RETAIN program in Minnesota to see if its services help injured or ill adults stay at work or return to work and reduce future workplace disability.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07037927

• Survey on disability and cognitive impairment in elderly people in Beijing

  This study is trying to find out what factors might lead to disability and memory problems in older adults living in Beijing, so they can help prevent these issues in the future.

  Recruiting Xuanwu Hospital, Beijing · Beijing · NCT06863727

• Exploring risk factors for disability and dementia in older Chinese adults

  This study is trying to find out what factors might lead to disability and dementia in older adults in China to help predict who might be at risk.

  Recruiting Xuanwu Hospital, Beijing · Beijing · NCT06472674

• Monitoring disability risk and aging in older adults in Beijing

  This study is trying to find out how to spot disability risks in older adults living in Beijing to help keep them healthier as they age.

  Recruiting Xuanwu Hospital, Beijing · Beijing · NCT06394817

• Evaluating chewing function in children with oral health issues

  This study is testing how chewing ability changes in children with oral health problems during treatment to see how it affects their eating habits and overall growth.

  Recruiting University Hospital, Clermont-Ferrand · Clermont-Ferrand · NCT05821140

• Longitudinal study of Victorian children and their parents

  This study is looking at the health and wellbeing of children born in Victoria and their parents over time to see how different factors affect their physical and mental health.

  Recruiting Murdoch Childrens Research Institute · Parkville, Victoria · NCT05394363

NIH-funded research (newest 40 of 118)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Sex differences in language impairment and services for children and adults

  A study examines why girls with language impairment may receive fewer speech services than boys and what that means for treatment.

  NIH research Father Flanagan's Boys' Home · Boys Town, United States · NIH-11591488

• How COVID school closures affected kids with or at risk for developmental differences

  This NIH grant follows children aged 4 to 15 and their families to see how pandemic school closures impacted emotional well-being and parenting over three years.

  NIH research University of Oregon · Eugene, United States · NIH-11575335

• Disability Community Engagement for All of Us Enrollment and Retention

  A patient-friendly plan to help people with disabilities join and stay in the All of Us program so researchers can learn how to tailor care.

  NIH research American Assn on Health and Disability · Rockville, United States · NIH-11539117

• Neural targets for improving function in Veterans with alcohol use disorder and mild brain injury

  This project tests a targeted brain-stimulation approach to help Veterans who have both alcohol use problems and mild traumatic brain injury improve daily functioning.

  NIH research Edward Hines Jr VA Hospital · Hines, United States · NIH-11518051

• Mediterranean-style eating and aging in people with multiple sclerosis

  This project looks at whether following a Mediterranean-style diet is linked to slower biological aging and less brain shrinkage in people living with multiple sclerosis.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11492803

• How where you live shapes midlife disability and thinking skills for low- and high-income adults

  This project compares how where people live affects disability and thinking skills in middle-aged adults in the US and other high-income countries.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11473589

• How COVID school closures affected children with or at risk for disabilities and their families

  This project follows children and their caregivers over time to understand how pandemic-related school closures changed children's behavior and parents' wellbeing.

  NIH research University of Oregon · Eugene, United States · NIH-11468613

• Does paying a family caregiver instead of an aide help people with disabilities stay at home and save public money?

  This project asks whether letting Medicaid beneficiaries with intensive home care needs pay a family member as their caregiver changes how long they can stay at home and how much public healthcare costs rise or fall.

  NIH research Duke University · Durham, United States · NIH-11444909

• Helping preschoolers build strong number skills and prevent math learning disability

  Trying a family-and-school approach to help preschool children build number skills and lower the risk of long-term math learning disability.

  NIH research University of Missouri-Columbia · Columbia, United States · NIH-11424705

• Disability, Diversity, and Data Sharing in Genomic Research for Better Chronic Disease Care

  This project aims to include people with disabilities in large genomic studies to help improve care for chronic diseases.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11422383

• Low-Load BFR Training to Help People with Advanced MS Improve Strength

  A randomized trial tests whether low-load resistance training with blood flow restriction can improve muscle strength for people with advanced multiple sclerosis.

  NIH research VA Eastern Colorado Health Care System · Aurora, UNITED STATES · NIH-11418736

• Disability community-engaged medical rehabilitation research center

  A nationwide collaboration to advance disability-focused rehabilitation research by working directly with the disability community to develop and share evidence-based interventions.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-11413602

• Intersecting Addiction and Disability Services – Alcohol

  This grant explores how alcohol use and access to treatment differ for adults with disabilities compared with those without disabilities.

  NIH research Brandeis University · Waltham, United States · NIH-11413465

• Disability Health Promotion Resources with AI to Help People with Disabilities in the Deep South

  This grant aims to use AI and behavioral insights to improve how researchers recruit, keep engaged, and use data from people with physical disabilities in the Deep South.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11412938

• Sex Differences in Language Impairment and Service Use

  This grant looks at why girls with language problems are less likely to get language services than boys, and how gender affects needs and service experiences.

  NIH research Father Flanagan's Boys' Home · Boys Town, United States · NIH-11406024

• Distance-based Exercise to Preserve Function in Breast Cancer Patients

  A plan to test a scalable exercise program that helps breast cancer patients stay active and maintain daily function during treatment.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-11400407

• Fibrinolytic and inflammatory drivers of severe trauma outcomes

  This grant looks at how the body's clot-busting system and immune cells interact after severe trauma to influence early organ failure and long-term disability.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11400058

• Mobility disability patients’ experiences with care and provider beliefs and how it affects health

  A study with adults who have mobility disabilities looks at how patient experiences with barriers and what providers know about disability relate to people’s health and well-being.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11399884

• Understanding genetic causes of intellectual disability across diverse populations

  Aiming to find gene variants that contribute to intellectual disability in people from African, Asian, and European backgrounds to improve diagnosis and future treatments.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11397280

• Understanding early cognitive skills in children with Down syndrome

  We’re studying how early thinking skills develop in young children with Down syndrome and what factors influence severe intellectual disability later on.

  NIH research Colorado State University · Fort Collins, United States · NIH-11396397

• Identifying disability-related barriers that affect health

  A five-year project at the University of Virginia will create and validate measures of the barriers that disability communities face in health care and daily life.

  NIH research University of Virginia · Charlottesville, United States · NIH-11393599

• Why girls with language problems get fewer school services than boys

  This project looks at why girls with developmental language disorder often receive fewer school speech-language services than boys.

  NIH research Father Flanagan's Boys' Home · Boys Town, United States · NIH-11390946

• Making primary care accessible for patients with communication disabilities

  Aimed at helping clinics reliably document and accommodate patients with communication disabilities so they receive equitable care.

  NIH research New York University School of Medicine · New York, United States · NIH-11386442

• Prepare for college success by improving executive function, self-advocacy, and self-identification for students with ASD or ADHD

  A technology-enabled program uses interactive stories to help high school students with autism or ADHD practice college-transition skills and reduce stress.

  NIH research Objective Ed, INC. · Wellington, United States · NIH-11379651

• Including Adults with Intellectual Disability in Precision Medicine

  This grant funds a study to help adults with intellectual disability participate more fully in precision medicine research and understand how to respect their consent and privacy while sharing useful health information.

  NIH research Syracuse University · Syracuse, United States · NIH-11376567

• Disability perspectives on how medical bias harms health

  This project will study how ableist attitudes in healthcare affect the care and health of adults with disabilities.

  NIH research Washington State University · Pullman, United States · NIH-11375046

• Improving MOUD Access and Outcomes for Medicare Beneficiaries with Disabilities

  This project studies how Medicare policies and care delivery affect access to medications for opioid use disorder and related outcomes among adults with disabilities.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11367993

• Home-based activity tracking to predict MS progression and support trials

  A study using wearable activity trackers to help predict disability progression in people with progressive multiple sclerosis and make clinical trials more efficient.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11364059

• Understanding sepsis-related disability and precision medicine

  This NIH grant aims to uncover why some sepsis survivors develop lasting physical disability and how age, sex, race, and gut bacteria influence recovery to guide personalized care.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11333827

• Engaging the Disability Community in a National Health Program

  This project helps people with disabilities join the 'All of Us' Research Program, which aims to gather health information from one million or more Americans to advance personalized medicine.

  NIH research American Assn on Health and Disability · Rockville, United States · NIH-11321804

• Gentle strength training with blood flow restriction for people with advanced MS

  This study will see if gentle, low-intensity strength exercises using a cuff to restrict blood flow help people with advanced multiple sclerosis gain muscle and move better.

  NIH research VA Eastern Colorado Health Care System · Aurora, UNITED STATES · NIH-11317022

• Mediterranean diet, biological aging, and multiple sclerosis progression

  This project looks at whether a Mediterranean-style diet links to slower biological aging and less brain shrinkage in people living with multiple sclerosis.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11310720

• COMPASS: helping stroke survivors transition home and reduce disability

  This program helps stroke survivors leaving inpatient rehab by providing home modifications and self-management coaching to reduce barriers and improve independence.

  NIH research Washington University · Saint Louis, United States · NIH-11310179

• Step It Up+: helping adults with intellectual disability be more active

  This 16-week program helps adults with intellectual disability use goal-setting, a web dashboard, and a support coach to increase daily steps and aerobic and strength activity.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11308675

• Understanding brain responses in children with autism and intellectual disability

  This project uses child-friendly EEG and eye-tracking to measure brain responses and looking patterns in 6–11-year-old children with autism and intellectual disability.

  NIH research Yale University · New Haven, United States · NIH-11269157

• Understanding and fixing SETD5-related brain problems in children with autism and intellectual disability

  Developing treatments that target the SETD5 gene to help young children with autism and intellectual disability.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11266125

• Including adults with intellectual disability in precision medicine

  This project creates a tailored consent toolkit to help adults with intellectual disability understand and take part in precision medicine studies.

  NIH research Syracuse University · Syracuse, United States · NIH-11264320

• Improving healthcare access for patients with communication disabilities

  This study is all about making it easier for people with communication disabilities to get the healthcare they need by helping doctors better understand and record their specific needs in their health records.

  NIH research New York University School of Medicine · New York, United States · NIH-11264097

• How a small sugar tag on proteins (O-GlcNAc) affects X-linked intellectual disability

  The team is looking at whether mutations in the OGT gene change a protein 'sugar tag' called O-GlcNAc and how those changes harm brain cells in people with X-linked intellectual disability.

  NIH research University of Georgia · Athens, United States · NIH-11262835

• How disability and chronic pain affect opioid overdose risk and prevention

  This project looks at whether adults with physical disabilities and chronic pain are more likely to have an opioid overdose and what can lower that risk.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11260200

Related topics

Quick answers

How many Disability clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in China (4 trials), Pakistan (3 trials), Australia (1 trial), France (1 trial), United States (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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