Condition

Environmental Exposure clinical trials and research

• 19Clinical trials
• 26NIH research projects
• 31Countries

Newest Environmental Exposure clinical trials

All recruiting trials (19)

• Cadmium Exposure in Pregnancy and Its Effect on Fetal Growth

  This observational study follows pregnant people to see how cadmium exposure relates to fetal growth and birth weight.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT07855237

• Probiotic supplement to lower serum PFAS levels in male firefighters

  A probiotic supplement containing Streptococcus salivarius is being tested to see if it lowers PFAS levels in male firefighters who have been exposed to PFAS.

  Recruiting Cambiotics ApS · Chicago, Illinois · NCT07846371

• Prenatal education to reduce environmental exposures during pregnancy

  Aimed at pregnant people, this program tests whether a classroom-style education can help reduce exposure to harmful pollutants from seafood and nearby pollution sources.

  Recruiting at 2 sites The University of Texas Medical Branch, Galveston · Galveston, Texas and 1 other locations · NCT07758114

• How environment and biology together predict health, aging, and death

  Researchers are following adults to see how living conditions and biology together relate to aging and life expectancy, by linking personal health data with environmental and social information over time.

  Recruiting Longevity Metrics, Inc. · Boulder, Colorado · NCT07646782

• PNEUMO-LIBS: Using tissue imaging and AI to explore causes of chronic lung diseases

  This study tests whether multi-element tissue imaging with LIBS, plus the AI tool IFF, can help doctors understand possible causes of chronic lung diseases in adults who have had a lung biopsy.

  Recruiting at 3 sites University Hospital, Grenoble · Grenoble and 2 other locations · NCT07597187

• Environmental and lifestyle effects on IVF and fertility treatment success

  This project will try to see if everyday environmental chemicals (like from plastics or air pollution) and personal habits (like diet and stress) change the chances of pregnancy and live birth for couples using fertility treatments such as IVF.

  Recruiting The Third Xiangya Hospital of Central South University · Changsha, Hunan · NCT07384676

• How environmental fungal exposure affects asthma, ABPA, and bronchiectasis

  This project will see if indoor and environmental fungal exposure is linked to disease control in adults with asthma, ABPA, or bronchiectasis and will compare findings to healthy adults.

  Recruiting First Affiliated Hospital of Ningbo University · Ningbo, Zhejiang · NCT07313904

• Eco-anxiety and suicide risk in youth in France

  This study tests whether climate-related anxiety is linked to suicidal thoughts in young people aged 16–24 in France.

  Recruiting Centre Hospitalier Esquirol · Limoges · NCT07305688

• Ambient air and noise effects on heart and metabolic health with green-space exercise and Mediterranean diet (METSGREEN)

  This project will test whether exposure to ultrafine air pollution and urban noise raises heart and metabolic risk and whether daily green-space exercise or a Mediterranean diet can lower that risk in 45–64-year-old Kaunas residents with early metabolic problems.

  Recruiting Vytautas Magnus University · Kaunas, Kaunas County and 1 other locations · NCT07111208

• Digital heat-adaptation messages from your primary care provider to help prepare for heatwaves

  This trial will test whether tailored digital messages sent by your family doctor or nurse practitioner help adult patients in Eastern Ontario change behaviors to protect themselves during heatwaves.

  Recruiting Hopital Montfort · Ottawa, Ontario · NCT07024628

• How exposure to heavy metals, nanoparticles, and emerging contaminants relates to allergic skin and systemic metal reactions

  This project will test whether adults with allergic contact dermatitis or systemic metal allergies have different levels of heavy metals, nanoparticles, and related blood and urine markers compared with healthy adults.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Bologna and 1 other locations · NCT06529913

• Barts Children's Environmental Health Clinic

  This service will try personal and home pollution monitoring plus tailored exposure-reduction plans for children aged 4–17 with chronic respiratory conditions to see if those steps lower their environmental exposures.

  Recruiting Queen Mary University of London · London and 1 other locations · NCT06447974

• Impact of environmental exposures on tumor risk in SDHx mutation carriers

  This study tests whether exposure to SDHi chemicals from work, home, or the environment affects tumor development in people with SDHx gene mutations.

  Recruiting Assistance Publique - Hôpitaux de Paris · Angers and 19 other locations · NCT06408402

• Assessing community exposure to environmental contaminants in the Ramapough Nation

  This study is trying to see how environmental pollution affects the health and food security of people in the Ramapough Nation to help create better food systems and health strategies for the community.

  Recruiting NYU Langone Health · New York, New York · NCT06315140

• Impact of microplastics on infant development and breastfeeding

  This study is trying to see how microplastics in mothers' bodies might affect their babies' growth and development in the first few months after birth.

  Recruiting Johns Hopkins Bloomberg School of Public Health · Baltimore, Maryland · NCT06107933

• Investigating early breast growth in girls aged 6 to 8 years and its environmental influences

  This study looks at why some girls aged 6 to 8 are developing breasts earlier than usual and what environmental factors might be causing it.

  Recruiting at 2 sites Lille Catholic University · Lambersart, Hauts-de-France and 1 other locations · NCT06083415

• Reconstructing schoolyards to boost children's physical activity and address climate change

  This study is testing if making schoolyards greener can help kids in Stockholm be more active and improve their health over three years.

  Recruiting Karolinska Institutet · Stockholm · NCT05865782

• Longitudinal study of Victorian children and their parents

  This study is looking at the health and wellbeing of children born in Victoria and their parents over time to see how different factors affect their physical and mental health.

  Recruiting Murdoch Childrens Research Institute · Parkville, Victoria · NCT05394363

• Examining health determinants and their impact on chronic diseases

  This study looks at how personal choices and community factors affect heart health and other long-term illnesses to see what really impacts people's health.

  Recruiting at 34 sites Population Health Research Institute · Rosario, Santa Fe Province and 33 other locations · NCT03225586

NIH-funded research (26)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Prenatal and early-life chemical exposures linked to faster cellular aging in children and adolescents

  Researchers will look at whether prenatal and early-life mixtures of chemicals and factors like diet and obesity speed up cellular aging in children and teens.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11469427

• Heart organoids reveal how environmental chemicals affect heart function

  A small research project uses lab-grown human heart tissue to study how environmental chemicals may change heart biology and function, aiming to identify early signs of heart problems.

  NIH research Michigan State University · East Lansing, United States · NIH-11424424

• Environmental exposures and inflammation in blood stem cells

  Many people exposed to pollution and environmental disasters may develop blood disorders due to inflammation and DNA changes in blood stem cells.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11411479

• Multimethod detection of brain micro- and nanoplastics in Alzheimer’s disease

  Researchers will look for tiny plastic particles in human brains and see how they relate to Alzheimer’s disease and neighborhood-level environmental risk.

  NIH research Arizona State University-Tempe Campus · Scottsdale, United States · NIH-11387111

• ECHO Measurement Core: Tools to track environmental exposures and child health

  A large NIH project at Northwestern builds better, culturally sensitive measurements to understand how early environmental exposures affect child health and development.

  NIH research Northwestern University · Chicago, United States · NIH-11371123

• S3E: A kid-friendly game to learn about indoor environmental health

  A mobile game helps middle-schoolers learn about everyday indoor environmental exposures and how to reduce health risks like asthma and lead poisoning.

  NIH research Dfusion, INC. · Scotts Valley, United States · NIH-11333036

• GeoHealth Hub: Environmental Health in Arab Region

  A research-and-training program in Jordan, Lebanon, and Morocco aims to understand how extreme weather, air pollution, dust, and water quality affect health in Arab-speaking regions and inform policies in the U.S.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11300260

• GeoHealth Hub: Environmental Exposure and Health in the Arab Region

  A multi-country effort in the Arab region to study how air pollution, dust, heat, and other environmental factors affect health, with training and collaboration across Arab and U.S. institutions.

  NIH research Jordan University/science & Technology · Irbid, Jordan · NIH-11300220

• How early-life environmental exposures affect biological aging in kids and teens

  This project looks at whether chemical exposures before birth, together with diet and body weight, speed up biological aging during childhood and adolescence.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11247923

• Understanding human metabolic types

  This project aims to map patterns of metabolites in people’s samples to define distinct metabolic “types” linked to diet, exercise, and environmental exposures.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11193986

• A mobile game to teach kids about environmental health risks

  This study is testing a fun mobile game designed for middle school kids to help them learn about the dangers of toxic things in their homes and how to stay healthy in their environment.

  NIH research Dfusion, INC. · Scotts Valley, United States · NIH-11182059

• Kids' mental health and exposure to tobacco, cannabis, and vaping smoke

  This project looks at how exposure to cigarette smoke, vaping vapor, and cannabis smoke at different ages relates to children's mood and behavior over time.

  NIH research Oklahoma State University Stillwater · Stillwater, United States · NIH-11129918

• Understanding How Early Life Experiences Affect Children's Health

  This project helps create better ways to measure how environmental factors influence the health and development of children.

  NIH research Northwestern University · Chicago, United States · NIH-11115685

• Air pollution and heart & metabolic health

  Researchers are looking at how breathing volatile chemicals from contaminated sites may harm adults' heart health and increase diabetes risk.

  NIH research University of Louisville · Louisville, United States · NIH-11112446

• How environmental chemicals affect chronic diseases through bioactive lipids

  This study is looking at how certain chemicals in our environment might affect our health by changing important fats in our bodies, which could lead to diseases like diabetes, heart problems, and cancer, and it’s for anyone interested in understanding how these toxins might impact their health.

  NIH research University of California at Davis · Davis, United States · NIH-11083623

• Reducing skin cancer risks in veterans exposed to UV light

  This study is looking at ways to help veterans with a type of skin cancer caused by sun exposure by improving a common treatment called photodynamic therapy, so they can get better results and healthier skin.

  NIH research Dayton VA Medical Center · Dayton, United States · NIH-11051941

• How early-life environmental exposures affect aging in children and adolescents

  This study is looking at how being around certain chemicals during pregnancy and early childhood might affect how kids age biologically, and it’s for families who want to understand how things like diet and weight can play a role in their children's health as they grow up.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11047757

• Investigating how lung immune cells respond to harmful environmental exposures

  This study is looking at how certain immune cells in the lungs respond to harmful things we breathe in, with the goal of finding new ways to help people with lung diseases like asthma and COPD feel better and recover faster.

  NIH research University of Nebraska Medical Center · Omaha, United States · NIH-11014958

• Investigating the health effects of a chemical spill in East Palestine.

  This study is all about understanding how a chemical spill in East Palestine, Ohio, might affect the health of people living there, and it invites local residents to help collect important information about the environment and their health, while also looking at the stress they might be feeling from the situation.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11014070

• Understanding how diet, exercise, and environment affect human metabolism

  This study is looking at how things like what we eat, how much we move, and our surroundings affect our body's metabolism, and it's for anyone interested in how their lifestyle choices might impact their health.

  NIH research University of California, San Diego · La Jolla, United States · NIH-10994353

• Exploring how environmental factors and genes contribute to Parkinson's disease risk.

  This study is looking at how things in our environment, like pesticides, and our genes might work together to increase the chances of getting Parkinson's disease, using special brain cells from patients to see how these toxins affect movement-related cells and their helpers in the brain, which could help us find better

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-10987053

• Investigating how exposure to tobacco, cannabis, and nicotine affects children's mental health over time

  This study looks at how being around tobacco smoke, cannabis smoke, and nicotine vapor affects kids' mental health from before they're born all the way through their teenage years, helping us understand the risks these exposures might pose as they grow up.

  NIH research Oklahoma State University Stillwater · Stillwater, United States · NIH-10977960

• A wearable device to track air quality and respiratory health.

  This study is testing a new wearable device that helps people with breathing problems, like asthma or COPD, by tracking air quality and lung health, so doctors can keep a close eye on their condition and step in when needed to help them stay healthy.

  NIH research Canairy LLC · Birmingham, United States · NIH-10914353

• Investigating how different environments affect eating and activity behaviors in mid-life.

  This study looks at how different places you spend time in can affect your eating and exercise habits as you reach middle age, helping to find out what encourages healthy choices and what doesn’t.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-10872991

• Investigating how arsenic and ultraviolet radiation together increase cancer risk

  This study is looking at how exposure to arsenic and UV light together might increase the risk of skin cancer, and it hopes to find ways to help prevent these cancers in people who might be affected.

  NIH research University of New Mexico Health Scis Ctr · Albuquerque, United States · NIH-10869994

• Investigating brain-derived vesicles for tracking ALS progression and environmental impacts.

  This study is looking at tiny particles in your blood to find clues about how ALS changes over time and how the environment might affect it, which could help improve how we track and treat the disease.

  NIH research Columbia University Health Sciences · New York, United States · NIH-10732756

Related topics

Quick answers

How many Environmental Exposure clinical trials are recruiting right now?

19, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 31 countries. The most sites are in France (5 trials), United States (5 trials), China (3 trials), Sweden (2 trials), Canada (2 trials). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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