COMPASS: helping stroke survivors transition home and reduce disability

Compass: A Novel Transition Program to Reduce Disability After a Stroke

NIH-funded research Washington University · NIH-11310179

This program helps stroke survivors leaving inpatient rehab by providing home modifications and self-management coaching to reduce barriers and improve independence.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-11310179 on NIH RePORTER

What this research studies

You would receive the COMPASS program at home right after leaving inpatient rehabilitation, including simple home modifications (for example, grab bars) and coaching to help you solve everyday barriers on your own. Participants are randomly assigned to COMPASS or to usual care so researchers can compare real-world outcomes. The team will track rehospitalizations, skilled nursing facility admissions, falls, and how well people reintegrate into their communities. Earlier feasibility and phase IIb work showed COMPASS can reduce home barriers and hinted at better health outcomes, and this larger trial aims to confirm those results and learn how to spread the program more widely.

Who could benefit from this research

Good fit: Adults (21+) who recently had a stroke and are leaving inpatient rehabilitation to return to a home setting are the ideal candidates.

Not a fit: People who are not returning to a private or modifiable home environment, who require long-term institutional care, or who are medically unstable may not benefit from this program.

Why it matters

Potential benefit: If successful, COMPASS could help people avoid falls, rehospitalizations, and long-term nursing care while increasing independence at home.

How similar studies have performed: Early feasibility work and a phase IIb trial showed reduced environmental barriers and suggested lower nursing-home admissions and deaths, but a larger randomized trial is needed to confirm benefits.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.