Low-Load BFR Training to Help People with Advanced MS Improve Strength

Who could benefit from this research

What this research studies

This study focuses on people with advanced MS who need assistance to walk or use a wheelchair. It tests a safe, low-intensity exercise approach (with blood flow restriction) to build strength, aiming to boost mobility and daily function. The researchers will compare this approach to standard care to see if it produces better gains in muscle strength and quality of life. The plan builds on prior evidence that lighter workouts with BFR can match the benefits of heavier exercise in other conditions, but now targets advanced MS under supervision at the VA East Central Health Care System. If successful, the results could offer a practical exercise option for a population with limited tolerance for intense training.

Why it matters

Where this research is happening

• VA Eastern Colorado Health Care System
  Aurora, United States Active

Researchers

• Principal investigator: Manago, Mark M — VA Eastern Colorado Health Care System
• Study coordinator: Manago, Mark M

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.