Understanding brain responses in children with autism and intellectual disability

Improving inclusion of individuals with intellectual disability in autism neuroscience research

NIH-funded research Yale University · NIH-11269157

This project uses child-friendly EEG and eye-tracking to measure brain responses and looking patterns in 6–11-year-old children with autism and intellectual disability.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-11269157 on NIH RePORTER

What this research studies

You or your child would take part in a child-friendly brain recording session that collects EEG and eye-tracking at the same time. The team plans to include 70 children with autism and intellectual disability and 70 matched children with intellectual disability without autism, all ages 6–11, using a behavior plan designed by a Board Certified Behavior Analyst to help kids stay comfortable. The visit uses automated measures of where a child looks and how they move, plus individualized rewards to support participation. Researchers will collect signals linked to face processing (the N170 event-related potential) and the proportion of looking to faces to better represent children who have often been excluded from past autism work.

Who could benefit from this research

Good fit: Ideal candidates are children aged 6–11 diagnosed with autism and co-occurring intellectual disability, and separately children with intellectual disability without autism for comparison.

Not a fit: Children outside the 6–11 age range, those without intellectual disability, or those unable to tolerate EEG or eye-tracking procedures may not be eligible or benefit.

Why it matters

Potential benefit: If successful, this work could improve neuroscience understanding for children with autism and intellectual disability and help make future brain-based tools and supports more relevant to them.

How similar studies have performed: EEG and eye-tracking have successfully measured face processing in autistic children without intellectual disability, but adapting these methods with behavioral supports for children with ASD plus intellectual disability is relatively novel.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Autistic Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.