Condition
Psoriatic Arthritis (PsA) clinical trials and research
As of November 12, 2026, Find a Trial lists 16 Psoriatic Arthritis (PsA) clinical trials that are recruiting, at sites in 11 countries (most in United States (3), United Kingdom (2), France (2)). By phase: Phase 4 (6), Phase 1 (1). The most active sponsors are Assistance Publique - Hôpitaux de Paris (2), University of Bonn (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 16Clinical trials
- 11Countries
Newest Psoriatic Arthritis (PsA) clinical trials
All recruiting trials (16)
-
Carotid ultrasound to guide prevention of heart disease in inflammatory rheumatic diseases
In people with inflammatory rheumatic diseases like RA, PsA, AxSpA, or SLE who are at modest cardiovascular risk, a carotid ultrasound test is used to see if they should start stronger lipid-lowering therapy to prevent heart problems.
-
Oxidative stress in autoimmune joint diseases
Researchers will see if oxidative stress and antioxidant markers differ in adults with rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis.
-
Preventing early joint damage in people with recent-onset psoriatic arthritis
This trial tests whether a TNF blocker (an adalimumab biosimilar) works better than injected methotrexate at preventing early joint damage in adults who recently developed psoriatic arthritis.
-
Self-management app to help people with inflammatory arthritis stay safe
A smartphone app from the French Rheumatology Society is being tested to help adults with rheumatoid arthritis or spondyloarthritis manage their treatments and safety while starting a new DMARD.
-
S-4321 in adults with autoimmune or immune-mediated diseases
This study tests S-4321 in adults with autoimmune conditions to see if it is safe and tolerable and to gather early data on how the drug behaves in the body and its initial effects on disease markers.
-
Combining the biologic ixekizumab with the weight-loss drug tirzepatide for people with psoriatic arthritis and overweight/obesity
This trial will test whether ixekizumab, tirzepatide (a weight-loss drug), or both together change skin, joint, and fat tissue in adults with psoriatic arthritis who are overweight or obese.
-
Doctor screening versus questionnaire screening for psoriatic arthritis in people with psoriasis
This study will test whether screening by a doctor or using short questionnaires finds more cases of psoriatic arthritis in adults with psoriasis.
-
Deucravacitinib added to current PsA treatment for difficult-to-control disease
This study tests whether adding deucravacitinib to a patient’s existing Psoriatic Arthritis treatment can improve symptoms and quality of life for adults with hard-to-control disease.
-
Comparing five advanced treatments for axial spondyloarthritis and psoriatic arthritis
This project will see how well bimekizumab, risankizumab, guselkumab, upadacitinib, or a TNF inhibitor work for adults with axSpA or PsA who have just started one of these medicines, using medical records and patient surveys.
-
Lowering JAK inhibitor doses in people with RA, PsA, or axSpA who are in low disease activity or remission
This study will test whether carefully lowering the dose of Janus kinase inhibitors keeps disease control as well as staying on the same dose in people with rheumatoid arthritis, psoriatic arthritis, or axial spondyloarthritis who are in remission or have low disease activity.
-
Personalized lab test to predict the best treatment for rheumatic diseases
This project tests a lab-based cell assay to see if it can predict which DMARD will work best for adults with autoimmune rheumatic diseases such as RA, PsA, axSpA, and GCA.
-
GLP-1 drugs vs. nutrition counseling for Psoriatic Arthritis with obesity and diabetes
This trial compares GLP-1 medications to nutrition counseling to see which approach best helps adults with psoriatic arthritis who also have obesity and type 2 diabetes.
-
Butantan live tetravalent dengue vaccine for people with autoimmune rheumatic diseases
This study will test whether a single dose of the Butantan live tetravalent dengue vaccine is safe and produces immune responses in clinically stable people aged 12–59 with autoimmune rheumatic diseases compared with matched healthy volunteers.
-
Investigating the Role of Y Chromosome Mutations in Autoimmune Diseases
This study is trying to see how changes in the Y chromosome might affect the immune system and contribute to autoimmune diseases like Giant Cell Arteritis and Polymyalgia Rheumatica.
-
A platform for collecting health data on ME/CFS and Long Covid
This study is trying to collect health information from adults with ME/CFS and Long Covid to help researchers better understand these conditions and improve future treatments.
-
Cohort for patients with psoriatic arthritis
This study is tracking 425 patients with their first signs of psoriatic arthritis over 10 years to see what factors lead to more severe disease and how to improve early treatment.
Related topics
Quick answers
How many Psoriatic Arthritis (PsA) clinical trials are recruiting right now?
16, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 11 countries. The most sites are in United States (3 trials), United Kingdom (2 trials), France (2 trials), Germany (2 trials), Brazil (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 6, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.