Condition

Acute Myocardial Infarction (AMI) clinical trials and research

• 26Clinical trials
• 16Countries

Newest Acute Myocardial Infarction (AMI) clinical trials

All recruiting trials (26)

• Can 1-Hz rTMS help with heart rhythm and inflammation after a heart attack?

  This trial tests whether daily 1-Hz repetitive transcranial magnetic stimulation can improve heart rate variability and reduce inflammation in people who have had an acute myocardial infarction, compared with a sham procedure.

  Recruiting Beijing Hospital · Beijing, Beijing Municipality · NCT07842770

• Trends and risk factors for adverse events after primary PCI in AMI patients over 20 years

  This study looks at real-world AMI patients who had a primary PCI to see how often serious events happen during a 2-year follow-up and what factors predict them.

  Recruiting Shanghai Zhongshan Hospital · Shanghai · NCT07833995

• SPIKE FLOW endocardial pacing lead safety and performance study

  This study tests whether the SPIKE FLOW temporary endocardial pacing lead is safe and effective in adults needing temporary pacing during heart-related conditions.

  Recruiting at 2 sites FIAB SpA · Acquaviva delle Fonti, Bari and 2 other locations · NCT07820072

• Predict Arrhythmia Risk with Intelligent Software

  Researchers are testing AI-powered predictions to see if clinicians can spot patients at risk for dangerous heart rhythms using bedside ECG data.

  Recruiting Catharina Ziekenhuis Eindhoven · Eindhoven, North Brabant · NCT07792694

• Left Ventricular Support and Advanced Monitoring in AMI–Cardiogenic Shock: Immediate Impella Use and PAC/Monitoring vs Standard Care

  In adults with heart attack-related cardiogenic shock, this trial tests whether using an Impella left ventricular assist device and/or protocolized pulmonary artery catheter monitoring improves survival compared with standard care.

  Recruiting Leipzig Heart Science gGmbH · Leipzig, Saxony · NCT07762560

• BRIDGE: Embedding consumer mHealth tools into cardiac rehab

  This study tests whether adding a mobile health tool to standard center-based cardiac rehab helps heart patients stay active and follow healthy habits.

  Recruiting University of Illinois Chicago · Chicago, Illinois · NCT07741396

• CRP Apheresis for infarct-related cardiogenic shock

  This study tests whether selectively removing C-reactive protein with apheresis, in addition to standard care, helps people with cardiogenic shock after a heart attack.

  Recruiting Leipzig Heart Science gGmbH · Leipzig, Saxony · NCT07687017

• Early Ga-68 FAPI PET/MR after a heart attack

  This study tests whether Ga-68 FAPI PET/MR done about 10 days after an acute myocardial infarction can predict how the heart will remodel over the next few months.

  Recruiting Ankara University · Ankara · NCT07684924

• ML-based diagnosis of blocked arteries in patients with a left bundle branch block

  Doctors are testing a machine learning tool that uses digital ECGs to see if a blocked coronary artery is present in patients with a left bundle branch block.

  Recruiting Konya City Hospital · Konya, Karatay · NCT07620119

• Non-stenting approach for acute heart attack with non-severe narrowing

  A large, multicenter trial will test whether standard medical therapy alone works as well as using drug-eluting stents in patients with a recent heart attack and a culprit artery with mild to moderate narrowing.

  Recruiting Harbin Medical University · Harbin, Heilongjiang and 47 other locations · NCT07567625

• Montelukast to reduce inflammation and heart damage after a heart attack

  This trial will try montelukast versus placebo to see if it lowers inflammation and limits heart muscle injury in adults aged 30–75 who have a STEMI treated within 6 hours with PCI or thrombolysis.

  Recruiting Phase 2 October 6 University · Al Mansurah · NCT07537868

• Cardiac CT imaging of coronary arteries and heart muscle after a heart attack

  This will test whether adding a cardiac CT scan soon after PCI can help predict which adults who recently had a heart attack are at higher risk for later problems.

  Recruiting at 2 sites Nanjing First Hospital, Nanjing Medical University · Nanjing, Jiangsu and 1 other locations · NCT07537296

• Dangerous heart rhythms after a heart attack

  This study will see how survival and treatment differ for adults who develop sustained ventricular tachycardia or ventricular fibrillation during a heart attack, comparing events that occur within 48 hours to those that occur later.

  Recruiting at 8 sites Poitiers University Hospital · Caen and 7 other locations · NCT07517523

• Routine use of Potassium Competitive Acid Blocker vs guideline GI protection in AMI with PCI

  This trial tests whether giving a potassium competitive acid blocker regularly after AMI with PCI and DAPT helps more than following standard GI protection guidelines.

  Recruiting Phase 3 Samsung Medical Center · Seoul · NCT07467213

• Magenta Elevate™ device for cardiogenic shock

  This trial tries the Magenta Elevate™ device to see if it can safely support people with cardiogenic shock caused by left ventricular failure.

  Recruiting at 8 sites Magenta Medical Ltd. · Tbilisi and 7 other locations · NCT07293923

• Ziltivekimab to reduce coronary plaque after a heart attack

  This study will test whether the anti-inflammatory drug ziltivekimab can reduce plaque buildup and improve plaque composition in people who recently had a heart attack and were treated with PCI.

  Recruiting Phase 3 ECRI bv · Bern · NCT07276282

• Using Advanced CT Scans and Blood Markers to Understand Heart Damage and Recovery After a Heart Attack

  Doctors are testing a combination of spectral CT imaging and blood biomarkers to see if they can better understand and predict how the heart heals after a heart attack in adults who recently had STEMI treated with PCI.

  Recruiting at 4 sites Instituto de Investigación Biomédica de Salamanca · Madrid and 3 other locations · NCT07268391

• Very early PCSK9 inhibition after a heart attack

  This project will try giving a PCSK9 inhibitor soon after a heart attack to people with multivessel coronary disease to see if it stabilizes vulnerable plaques and lowers the chance of another heart event.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07208006

• 18F‑Pentixafor PET/MR and cardiac MRI to check heart microcirculation after a first heart attack

  This will test whether 18F‑Pentixafor PET/MR plus cardiac MRI can reveal small‑vessel injury and recovery in people who had a first heart attack treated with emergency PCI.

  Recruiting The Affiliated Hospital of Qingdao University · Qingdao, Shandong · NCT07130409

• Hemodynamic resuscitation with a Swan-Ganz catheter in cardiogenic shock.

  This will try using a Swan‑Ganz (pulmonary artery) catheter to guide medicines and fluids in adults who have cardiogenic shock after a heart attack.

  Recruiting Bach Mai Hospital · Hanoi · NCT07062744

• Using the TyG index to detect early microvascular blockage after emergency PCI for heart attack

  This project will test whether the TyG (triglyceride-glucose) index can help doctors spot early small-vessel blockage (microvascular obstruction) in people treated with emergency PCI for a heart attack.

  Recruiting The Third Xiangya Hospital of Central South University · Changsha, Hunan Province,China · NCT07042321

• Morphine injection near the stellate ganglion to reduce heart damage after a heart attack

  This trial will try giving a single morphine injection around the stellate ganglion to see if it lowers heart muscle damage and improves recovery in adults with an ST‑elevation heart attack treated with PCI.

  Recruiting at 2 sites The Second Hospital of Anhui Medical University · Hefei and 1 other locations · NCT07023679

• Intervention for heart attack patients with gum disease

  This study tests if treating gum disease with surgery can help heart attack patients feel better and improve their recovery.

  Recruiting Shanghai 10th People's Hospital · Shanghai, Shanghai Municipality · NCT06745141

• Fast discharge after heart attack treatment

  This study is testing if patients who have a heart attack can safely leave the hospital just 24 hours after treatment instead of the usual 72 hours.

  Recruiting at 6 sites Medical University Innsbruck · Wiener Neustadt, Lower Austria and 7 other locations · NCT06744322

• Aspirin alone versus aspirin plus fondaparinux before early coronary angiography for NSTEMI

  This trial will test whether giving aspirin alone or aspirin plus the anticoagulant fondaparinux before early coronary angiography is better and safer for adults with NSTEMI.

  Recruiting at 7 sites Phase 4 University of Aarhus · Herning, Region Midt and 9 other locations · NCT06710184

• Comparing two methods for diagnosing heart conditions in patients with non-ST elevation acute coronary syndrome

  This study is testing if a non-invasive heart scan can safely and effectively diagnose heart conditions in patients with certain types of heart attacks, compared to the traditional invasive method.

  Recruiting at 6 sites Copenhagen University Hospital, Rigshospitalet · Copenhagen, Hellerup and 5 other locations · NCT06101862

Related topics

Quick answers

How many Acute Myocardial Infarction (AMI) clinical trials are recruiting right now?

26, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 16 countries. The most sites are in China (9 trials), Germany (3 trials), Turkey (Türkiye) (2 trials), Denmark (2 trials), Egypt (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 2: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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