Condition

Acute Coronary Syndromes clinical trials and research

• 19Clinical trials
• 1NIH research projects
• 20Countries

Newest Acute Coronary Syndromes clinical trials

All recruiting trials (19)

• Aspirin 50 mg vs 100 mg with a P2Y12 inhibitor after PCI

  This trial tests whether a 50 mg daily aspirin dose, when used with a P2Y12 inhibitor after PCI, works as well as 100 mg with similar safety for people staying on DAPT for 12 months.

  Recruiting Jilin University · Changchun, Jilin · NCT07846462

• Early Triple Lipid-Lowering Therapy After ACS

  This trial tests whether adding bempedoic acid to high-intensity statin and ezetimibe within 72 hours after PCI helps more adults with acute coronary syndrome reach LDL-C goals than the standard two-drug approach.

  Recruiting Phase 4 Taipei Medical University Hospital · Taipei, Taipei City · NCT07824323

• Smartphone AI help for prehospital ECG readings

  This study tests whether using a smartphone AI (GPT-4o) to help prehospital providers read 12-lead ECGs improves accuracy in diagnosing acute coronary syndromes and related conditions.

  Recruiting École Supérieure de Soins Ambulanciers - College of Higher Education in Prehospital Care · Murten/Morat, Canton of Fribourg · NCT07810686

• Early single antiplatelet therapy after IVUS-guided PCI in ACS

  This study tests whether stopping aspirin early and continuing a potent P2Y12 inhibitor alone is safe and effective after IVUS-guided PCI in people with acute coronary syndrome.

  Recruiting Phase 4 Gyeongsang National University Hospital · Jinju, Gyeongsangnam-do · NCT07684742

• Local and systemic macrophage activation in coronary and peripheral artery disease

  This study tests whether macrophage activity inside coronary and peripheral arteries relates to circulating monocyte subtypes in people with stable and acute artery disease.

  Recruiting Maria Cecilia Hospital · Cotignola, Ravenna · NCT07588295

• Long-term P2Y12 inhibitor monotherapy and blood clotting after angioplasty

  This trial will test whether specific P2Y12 drugs and reduced doses given alone keep platelet activity in a safe therapeutic range for people who completed initial dual antiplatelet therapy after PCI.

  Recruiting Phase 3 Cardiocentro Ticino · Lugano, Ch/ti · NCT07582835

• Coronary Laser Atherectomy Registry in an International Network

  This registry tests how well Excimer Laser Coronary Atherectomy (ELCA) works in real-world PCI for people with stable or acute coronary conditions across multiple countries.

  Recruiting Ceric Sàrl · Madrid · NCT07348341

• Hand fan to prevent ticagrelor-related breathlessness

  This study will try to see if using a handheld fan can reduce breathing discomfort in adults with acute coronary syndrome who are starting ticagrelor.

  Recruiting Acibadem University · Istanbul, Avcılar and 1 other locations · NCT07268859

• Oregano and basil leaves for people with unstable angina

  This project will see if eating more oregano and basil reduces inflammation and improves blood lipid and urine polyphenol levels in people who recently had unstable angina.

  Recruiting Shahid Beheshti University of Medical Sciences · Tehran, Tehran Province · NCT07123181

• Understanding the connection between stroke and heart issues

  This study is trying to understand how strokes affect heart health and overall well-being in stroke patients to find new ways to help them recover better.

  Recruiting Tongji Hospital · Wuhan, Hubei · NCT06954103

• Orticumab to reduce coronary artery inflammation after a heart attack

  This tests whether orticumab can reduce coronary artery inflammation over six months in people who had a heart attack and show high inflammation on coronary CT angiography.

  Recruiting at 39 sites Phase 2 Abcentra · Los Angeles, California and 40 other locations · NCT06927739

• Assessing the Predictive Role of Flow Mediated Dilatation in Acute Coronary Syndromes

  This study is testing if measuring blood vessel response can help predict outcomes for patients with serious heart conditions like heart attacks.

  Recruiting Aristotle University Of Thessaloniki · Thessaloniki · NCT06890013

• Testing UDP-003 for safety and effectiveness in healthy individuals and patients with heart conditions

  This study is testing a new drug called UDP-003 to see if it's safe and effective for both healthy people and those with heart conditions, specifically looking at its ability to reduce plaque buildup in the arteries.

  Recruiting Early Phase 1 Cyclarity Therapeutics, Inc. · Adelaide, South Australia and 2 other locations · NCT06813339

• Comparing Atorvastatin and Rosuvastatin's effects on Vitamin D levels in heart patients

  This study tests whether taking Atorvastatin or Rosuvastatin affects Vitamin D levels in heart patients with acute coronary syndrome.

  Recruiting Phase 4 King Edward Medical University · Lahore, Punjab Province · NCT06765265

• National registry for heart attacks in young adults in Serbia

  This study looks at heart attacks in young adults under 45 in Serbia to see what causes them and how to improve treatment and prevention.

  Recruiting at 11 sites Cardiology Society of Serbia · Belgrade and 10 other locations · NCT06753591

• Evaluating early lipid-lowering therapy in acute coronary syndrome patients

  This study is testing if starting a new cholesterol-lowering treatment early can help Chinese patients with acute coronary syndrome have better heart health and lower cholesterol levels compared to other treatments.

  Recruiting Chinese PLA General Hospital · Beijing, Beijing Municipality · NCT06738758

• Home-based cardiac rehabilitation with family empowerment for people after acute coronary syndrome

  This program will test whether a home-based cardiac rehab plan that trains and involves family members helps adults recovering from acute coronary syndrome improve exercise capacity and quality of life.

  Recruiting Gadjah Mada University · Sleman, Special Region of Yogyakarta and 1 other locations · NCT06625463

• Using low-dose IL-2 to reduce vascular inflammation in heart attack patients

  This study is trying to see if low-dose IL-2 can help heart attack patients by reducing inflammation and preventing serious heart problems after their initial treatment.

  Recruiting Cambridge University Hospitals NHS Foundation Trust · Cambridge, Cambridgeshire · NCT06427694

• Registry of Acute Coronary Syndromes in Ferrara

  This study is collecting information about how patients with acute coronary syndromes are treated in Ferrara, Italy, to better understand their care and outcomes.

  Recruiting University Hospital of Ferrara · Cona, Ferrara · NCT02438085

NIH-funded research (1)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Polypill approach after a heart attack to simplify and improve aftercare

  A research study will test a single combined pill to help people take their post-heart-attack medicines reliably.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11387564

Related topics

Quick answers

How many Acute Coronary Syndromes clinical trials are recruiting right now?

19, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 20 countries. The most sites are in China (3 trials), Italy (3 trials), Switzerland (2 trials), Spain (2 trials), United Kingdom (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 3, Phase 3: 1, Phase 2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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