Comparing Atorvastatin and Rosuvastatin's effects on Vitamin D levels in heart patients
Official title: Impact of Atorvastatin Versus Rosuvastatin on 25 Hydroxy Vitamin D Levels in Patients With Acute Coronary Syndrome
Run by King Edward Medical University · NCT06765265 · Data updated 2026-11-12
This study tests whether taking Atorvastatin or Rosuvastatin affects Vitamin D levels in heart patients with acute coronary syndrome.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 152 (estimated) |
| Sponsor | King Edward Medical University Academic / other |
| Locations | 1 site (Lahore, Punjab Province) |
| Status | Recruiting |
| Started | January 5, 2025 |
| Main results expected | January 1, 2026 |
| Study ends | January 1, 2026 |
| Registry record updated | March 11, 2025 |
| Trial ID | NCT06765265 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients with acute coronary syndrome and 25 OH-Vitamin D levels between 30-70 ng/ml.
✕Probably not a fit
Patients with conditions such as hypercalcemia, pregnancy, or those who have used certain medications recently may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effects of Atorvastatin versus Rosuvastatin on Vitamin D levels in patients diagnosed with acute coronary syndrome. A total of 152 patients with normal Vitamin D levels will be randomly assigned to receive either Atorvastatin (40 mg/day) or Rosuvastatin (20 mg/day) for a duration of six months. The primary outcome will be the change in 25-hydroxy Vitamin D levels after the treatment period. This study aims to provide insights into the relationship between statin therapy and Vitamin D levels in this patient population.
Why it matters
Potential benefit: If successful, this study could help optimize treatment strategies for patients with acute coronary syndrome by improving their Vitamin D levels.
How similar studies have gone: While there is existing research on statins and Vitamin D, this specific comparison of Atorvastatin and Rosuvastatin in acute coronary syndrome patients is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Acute Coronary Syndrome 25 OH-Vitamin D levels between 30-70ng/ml Exclusion Criteria: Hypercalcemia hypocalcemia pregnancy lactation hypersensitivity to statins hypothyroidism Deranged LFTs \& RFTs Use of following within last 3 months (Vitamin D Supplements, lipid lowering drugs, anti-obesity drugs, corticosteroids)
Where it's running
-
King Edward Medical University
Lahore, Punjab Province, Pakistan Recruiting
Study contacts
- Principal investigator: Ali Hussnain — King Edward Medical University
- Study coordinator: Ali Hussnain
- Email: ahshah12@hotmail.com
- Phone: +923317641096
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.