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Clinical trials and research at University of Nebraska Lincoln

• 3Clinical trials
• 88NIH research projects
• 1Country

Newest trials

All recruiting trials (3)

• Healthy Children, Healthy Communities: Helping rural family childcare homes improve preschoolers' diets

  This program will see if online training, one-on-one coaching, and mealtime feedback for rural family childcare providers helps 3–5-year-old children eat more fruits and vegetables and supports healthier mealtime practices.

  Recruiting University of Nebraska Lincoln · Lincoln, Nebraska · NCT07160530

• Effects of beef consumption on brain health and cognitive function

  This study is testing how eating different amounts of beef affects brain health and thinking skills in healthy young adults aged 19 to 24.

  Recruiting University of Nebraska Lincoln · Lincoln, Nebraska · NCT06690892

• Motivating bystanders to prevent sexual assault and reduce alcohol use

  This study is testing a new program to see if it can help young adults step in to prevent sexual assault and reduce their alcohol use.

  Recruiting University of Nebraska Lincoln · Lincoln, Nebraska · NCT05873413

NIH-funded research (newest 40 of 88)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Identify Unknowns with Long-Read Bioinformatics for Vet Diagnostic Labs

  A hands-on training program using long-read sequencing data to help veterinary diagnostic labs improve pathogen detection and outbreak response.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11528004

• Enhancing pathogen and AMR detection with a new sequencing instrument

  A veterinary lab is getting a high-throughput sequencing machine to help detect drug-resistant bacteria and emerging pathogens in animals and food, improving public health readiness.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11527014

• How childhood hardship and neighborhood features affect adult alcohol and tobacco misuse

  This project looks at whether adults who experienced tough childhoods are more likely to misuse alcohol or tobacco later in life and whether where they live makes that risk higher or lower.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11525855

• Nicotine's effect on drinking sweetened alcoholic drinks

  This project looks at whether nicotine makes people drink more sweetened alcoholic drinks, especially among people who smoke or drink heavily.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11525854

• MiRNA roles in age-related muscle loss and NMJ health

  This project explores how small RNA molecules called miRNAs influence muscle aging and the neuromuscular junction in adults.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11452282

• MG53 protein to protect aging muscles during disuse

  A small research project will explore whether increasing MG53 protein can help prevent muscle loss during periods of inactivity in aging, with the goal of protecting muscle health.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11406337

• Neddylation and blood vessel health in adults

  Aims to understand how a tiny cellular switch called neddylation keeps blood vessels healthy and what goes wrong in vascular disease.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11403834

• Understanding how microscopic cellular organizers shape cell structure

  A scientist will study how tiny structures inside cells organize themselves to control the cell’s shape and division, which could reveal new ways to understand diseases that involve cell division and movement.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11395578

• Next-generation models to understand RNA shapes, how they bind partners, and catalyze reactions

  A funded project at theUniversity of Nebraska–Lincoln aims to build better computer and experimental models of RNA to predict its 3D shape, how it binds molecules, and how it helps chemical reactions, with the goal of creating new RNA-based tools and therapies.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11372186

• Multimodal wearable to detect health changes in chronic lung and heart conditions

  A wearable device will passively monitor multiple body signals to help doctors distinguish true health problems from normal daily changes in people with COPD and related heart conditions.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11367524

• How cells build the centers that organize their internal skeleton

  This project looks at how tiny cellular organizers called microtubule organizing centers form so scientists can better understand infections like African sleeping sickness and basic cell division problems.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11361752

• Ribosome Heterogeneity Lab: Building Tools to Map How Ribosomes Differ Across Cells

  A lab at the University of Nebraska Lincoln is developing new methods to reveal how ribosomes vary in composition and modifications across different cell types and states.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11360093

• Cellphone-based intervention to prevent drug use among youth experiencing homelessness

  A mobile-program aims to help homeless youth manage emotions and coping in ways that reduce alcohol and drug use.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11358301

• Synthetic chemistry and biology tools to study proteins and modify their function

  New ways to modify proteins and study how they work could lead to better therapies, using lab-made amino acids and genetic code tricks.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11357633

• Methamphetamine effects on the hippocampus (memory center)

  This project uses advanced brain scans to look for small changes in the hippocampus of adults who use methamphetamine to help explain memory problems.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11335644

• How stress and sexual cues affect substance use in young women

  This project looks at how stress, sexual situations, and mood link to cravings and faster progression to problem substance use in young women.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11335641

• Long-term network supporting rural people affected by substance use

  This project keeps and connects a long-term group of rural people who use drugs so researchers can learn about causes, testing, prevention, and treatments and make it easier for you to join future studies.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11335635

• Rural programs to prevent and treat substance use in young women

  Programs and tools are being developed to help reduce cravings and stop substance use from escalating in young women living in rural areas.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11335632

• Neural factors that shape teen weight gain and how environments influence them

  A long-term study following teens to understand how brain control, rewards, and environments combine to affect future weight gain.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11335608

• Multilevel rural community approach to improve kids’ diet in family childcare homes

  A large study will test a community-based program in rural family childcare homes to help 3- to 5-year-olds eat healthier and maintain a healthier weight.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11332914

• Chemical ways to study how body peptides talk to cells in disease

  Researchers will develop chemical tools to map how natural body peptides signal between cells, with potential implications for treating diseases.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11331180

• Seeing enzymes change in real time to learn how they work and are controlled

  Researchers are using advanced time-resolved crystallography and computer simulations to watch enzymes—including ones linked to Parkinson's disease and antibiotic breakdown—change during reactions to better understand their behavior.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11325316

• Keeping mitochondria working properly

  This project looks at how cells keep mitochondria healthy to help prevent or treat conditions like ALS, Parkinsonism, heart problems, and some cancers.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11324522

• How nicotine's bodily signals and cues make quitting harder

  This project looks at how the internal effects of nicotine and everyday cues (like places, people, and stress) push people toward heavier smoking or vaping and how to lessen that for people trying to quit.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11319896

• Investigating brain changes in people who misuse methamphetamine

  This study is looking at how using methamphetamine affects the brain, especially the part that helps with memory, and it’s for people who want to understand more about how this drug impacts their thinking and memory skills through safe brain scans.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11249108

• How poxviruses hijack cell division and antiviral defenses

  Researchers are learning how poxvirus proteins change cell division and block antiviral defenses to help people affected by poxvirus infections.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11238426

• A virtual map of how the human immune system works

  Researchers are building a computer-based 'virtual immune system' to better understand immune behavior and help guide safer, faster treatments for people with immune-related conditions.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11234267

• Picture-based brain-computer communication for children with severe speech and physical impairments

  This project develops and uses a picture-based brain-computer system to help children with severe speech and physical impairments control communication devices using attention-related brain signals.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11228417

• Understanding how tunneling nanotubes help cells communicate

  This study is looking at tiny structures called tunneling nanotubes that help cells talk to each other, and it aims to understand how they are made and how they work, which could help us learn more about how cancer cells avoid treatment.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11222311

• Copper balance in liver metabolism and fatty liver disease

  Poor copper balance in the liver may drive worsening fatty liver disease, and restoring copper could help liver health in people at risk.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11210162

• Developing a new method to discover therapeutic antibodies

  This study is working on a new way to find and understand antibodies in your blood that can help treat diseases like cancer and infections, with the goal of discovering better treatments for patients like you.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11202211

• A Smart Wearable Device to Track Body Rhythms

  This project is creating a new wearable device to help tell the difference between daily changes in health and serious worsening of chronic conditions like COPD.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11193962

• Improving healthy eating habits in rural children through family childcare homes

  This study is all about helping kids aged 0-5 in rural family childcare homes eat healthier by training caregivers to encourage good eating habits and teach children how to listen to their bodies when they're hungry or full.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11193934

• Hormone-linked changes in the hippocampus and memory in women

  This project looks at whether normal monthly hormone swings change tiny hippocampal brain structure and memory in women aged 18–40.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11180660

• How infections and cancer change cell metabolism over time

  Researchers are using computer models to track how infections and cancer change cell metabolism to help people with cancer or infectious diseases.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11144409

• Understanding how iron-sulfur proteins help control cellular functions and respond to stress

  This study looks at how certain proteins help keep our cells healthy and respond to stress, which could be important for people with conditions like cancer and diabetes, and aims to find out how these proteins work so we can better understand and treat these diseases.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11137228

• Understanding and Modifying Proteins for Health

  This work explores new ways to understand and change proteins in our bodies, which are key to many biological processes and diseases.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11133040

• How the Liver Processes Antisense Oligonucleotide Medicines

  This research explores how the liver handles a type of medicine called antisense oligonucleotides, which are used to treat various diseases by targeting specific genes.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11131213

• Pooling samples to test for infections faster

  This work uses pooled samples so labs can screen more people for infections like HIV and COVID-19 faster and with fewer tests.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11127523

• Understanding how different dietary fibers affect gut bacteria

  This study is looking at how different types of dietary fibers affect the bacteria in our gut, which can help prevent health issues like obesity and heart disease, and it aims to create a tool that gives personalized nutrition advice based on each person's unique gut bacteria.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11126988

Quick answers

How many clinical trials run by University of Nebraska Lincoln are recruiting right now?

3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →