Investigating brain changes in people who misuse methamphetamine
Hippocampal Alteration in Methamphetamine Misuse
['FUNDING_OTHER'] · UNIVERSITY OF NEBRASKA LINCOLN · NIH-11249108
This study is looking at how using methamphetamine affects the brain, especially the part that helps with memory, and it’s for people who want to understand more about how this drug impacts their thinking and memory skills through safe brain scans.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF NEBRASKA LINCOLN (nih funded) |
| Locations | 1 site (LINCOLN, UNITED STATES) |
| Trial ID | NIH-11249108 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how methamphetamine misuse affects the brain, particularly the hippocampus, which is crucial for memory. Using advanced imaging techniques like magnetic resonance elastography (MRE), the study aims to detect subtle changes in brain structure that traditional methods may miss. By examining the relationship between methamphetamine use and cognitive impairments, the research seeks to provide insights into the underlying mechanisms of memory deficits associated with this substance. Participants may undergo noninvasive imaging to assess their brain health and cognitive function.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have a history of methamphetamine use or misuse.
Not a fit: Patients who do not misuse methamphetamine or have no history of substance use may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for cognitive impairments in individuals who misuse methamphetamine.
How similar studies have performed: While some studies have explored brain changes in substance misuse, this approach using MRE to assess microstructural changes is relatively novel and has not been extensively tested.
Where this research is happening
LINCOLN, UNITED STATES
- UNIVERSITY OF NEBRASKA LINCOLN — LINCOLN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SCHWARB, HILLARY — UNIVERSITY OF NEBRASKA LINCOLN
- Study coordinator: SCHWARB, HILLARY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.