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Clinical trials and research at Radboud University Medical Center

• 64Clinical trials
• 1New in 30 days
• 13Countries

Newest trials

All recruiting trials (64)

• How incretin treatments affect muscle mass and function in people with overweight or obesity

  This study will see how drugs like semaglutide and tirzepatide influence fat-free mass, muscle strength, and physical function in adults with overweight or obesity.

  Recruiting Radboud University Medical Center · Amsterdam and 1 other locations · NCT07929831

• Affordable, tailored physical therapy for financially vulnerable people after trauma

  We’re testing whether a patient-friendly, low-cost approach to physical therapy helps adults with trauma injuries who are financially vulnerable maintain or improve their quality of life.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland · NCT07795216

• Timing of Immunotherapy in Melanoma

  This trial tests whether starting standard melanoma immunotherapy earlier in the day (before 10 am) versus later in the day (after 1 pm) makes a difference for patients with unresectable or metastatic melanoma.

  Recruiting Radboud University Medical Center · Amsterdam and 4 other locations · NCT07696715

• Fiber to boost gut bacteria and immunotherapy response in advanced melanoma

  In people with advanced melanoma starting immunotherapy, this trial tests whether increasing dietary fiber can grow beneficial gut bacteria and improve treatment response.

  Recruiting Phase 2 Radboud University Medical Center · Nijmegen, Gelderland and 1 other locations · NCT07686835

• Exercise to Boost Immunotherapy Response in Advanced Kidney Cancer

  In this pilot study, adults with advanced renal cell carcinoma receiving first-line nivolumab plus ipilimumab will try a supervised HIIT exercise program to see if it helps them better tolerate treatment and possibly improve immune and clinical outcomes.

  Recruiting at 2 sites Radboud University Medical Center · Arnhem, Gelderland and 1 other locations · NCT07680556

• Modafinil for Debilitating Fatigue in Quiescent IBD

  A study will test whether modafinil can help adults with Crohn’s disease or ulcerative colitis who feel very fatigued even when their IBD is quiet.

  Recruiting at 2 sites Phase 2/3 Radboud University Medical Center · Arnhem, Gelderland and 1 other locations · NCT07582458

• Prospective Prostate Cancer Infrastructure for High-Risk and Metastatic Disease

  This study will collect long-term real-world data and biomaterials from men with high-risk localized or metastatic hormone-sensitive prostate cancer to understand everyday treatment patterns and quality of life.

  Recruiting Radboud University Medical Center · Nijmegen · NCT07560748

• Personalized drug combos for advanced thyroid cancer

  This phase Ib study tests whether customized drug combinations, chosen from existing approved medicines based on a patient’s tumor genetics, can be safely given to people with advanced thyroid cancer when standard options are limited.

  Recruiting Phase 1 Radboud University Medical Center · Nijmegen · NCT07485569

• Plant-based versus animal-based oral nutritional supplements

  We're testing whether plant-based nutrition drinks work as well as animal-based drinks for hospitalized adults at high risk of malnutrition.

  Recruiting at 2 sites Radboud University Medical Center · Nijmegen, Gelderland and 1 other locations · NCT07399886

• Detecting tiny amounts of prostate cancer left after prostatectomy

  This pilot will test whether a custom prostate-specific ctDNA blood test can find minimal residual disease after prostatectomy in men with high-risk prostate cancer.

  Recruiting Radboud University Medical Center · Nijmegen · NCT07334275

• Atomoxetine to reduce freezing of gait in Parkinson's disease by targeting the brain's noradrenaline system

  This trial will test whether the medication atomoxetine can reduce how often or how severely people with Parkinson's disease experience freezing of gait.

  Recruiting Phase 3 Radboud University Medical Center · Nijmegen, Gelderland · NCT07316296

• Predicting outcomes from coronary OCT images with AI

  This project will try to see if details from coronary OCT scans and an AI tool can predict long-term outcomes in people with coronary artery disease.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland · NCT07293858

• How the immune system responds to sepsis and affects long-term health

  This study will try to identify different immune response types in adults with sepsis by collecting blood samples and tracking their short- and long-term outcomes.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland · NCT07273344

• Prehospital triage for intermediate- to high-risk NSTE-ACS using HEAR score and hs troponin

  This trial tests whether directing certain intermediate- to high-risk chest-pain patients straight to a PCI center can be faster and cost-effective while not increasing major heart events.

  Recruiting at 2 sites Radboud University Medical Center · Haps and 2 other locations · NCT07252245

• How changing PEEP affects breathing drive and effort during pressure‑support ventilation

  We will test whether changing PEEP levels changes neural respiratory drive and inspiratory effort in adults on pressure‑support ventilation for moderate‑to‑severe ARDS or acute hypoxemic respiratory failure.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland · NCT07203781

• Personalized tool to predict lymph node spread in early endometrial cancer

  This study will test whether using the ENDORISK risk model helps doctors better predict lymph node spread before surgery for people with early-stage endometrial cancer.

  Recruiting at 11 sites Radboud University Medical Center · Arnhem, Gelderland and 13 other locations · NCT07200466

• Obinutuzumab to reduce PLA2R antibodies in primary membranous nephropathy

  We will try obinutuzumab to see if it quickly lowers anti‑PLA2R antibody levels in adults with high‑risk primary membranous nephropathy who still have heavy proteinuria despite ACEi/ARB treatment.

  Recruiting Phase 2/3 Radboud University Medical Center · Nijmegen · NCT07163611

• Daily protein plus weekly resistance training to prevent muscle loss after bariatric surgery

  The trial will test whether taking a daily protein supplement and doing one supervised resistance workout each week helps people having bariatric surgery keep their muscle mass.

  Recruiting Radboud University Medical Center · Amsterdam and 1 other locations · NCT07156552

• Using levosimendan to shorten time on a ventilator

  This will test whether giving levosimendan to adults in the ICU who have failed a breathing trial helps them get off the ventilator sooner.

  Recruiting at 6 sites Phase 4 Radboud University Medical Center · Arnhem, Gelderland and 7 other locations · NCT07105202

• Smart swallowable pill to measure gut oxidation in colon inflammation and cancer

  This pilot will test whether a swallowed sensor pill can measure gut oxidation levels in people with ulcerative colitis or colorectal cancer before and three months after treatment.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland · NCT07046468

• Personalized lifestyle support with an app for adults seeing their GP for depression symptoms

  This study tests whether a smartphone app that supports personalized lifestyle changes can help reduce depression symptoms for adults who visit their GP.

  Recruiting at 3 sites Radboud University Medical Center · Nijmegen, Gelderland and 2 other locations · NCT07022184

• TGW211 click-cleavable imaging for HER2-positive cancers

  This trial tries TGW211, a trastuzumab-based agent with a click-cleavable tag, to see if it gives clearer SPECT scans for adults with HER2-positive cancers.

  Recruiting Early Phase 1 Radboud University Medical Center · Nijmegen, Gelderland · NCT07009184

• Slow-SPEED: Can a smartphone app help people with prodromal Parkinson's stay more active?

  This trial tests whether a remote smartphone app can help people with a LRRK2 G2019S or GBA1 N370S mutation increase daily activity and see if exercise might slow prodromal Parkinson's signs.

  Recruiting Radboud University Medical Center · Rochester, New York and 1 other locations · NCT06993142

• Long-term follow-up of patients with facioscapulohumeral muscular dystrophy

  This study follows 200 people with facioscapulohumeral muscular dystrophy for ten years to see how the disease changes over time and to find better ways to treat it.

  Recruiting Radboud University Medical Center · Nijmegen · NCT06911190

• Heart registry for patients after coronary interventions in South East Netherlands

  This study is creating a registry to help doctors better understand and treat patients in South East Netherlands who have had heart procedures, aiming to reduce their risk of future heart problems.

  Recruiting at 4 sites Radboud University Medical Center · Heerlen, Limburg and 3 other locations · NCT06512493

• Effect of Methylphenidate on KBG Syndrome in Children and Adolescents

  This study is testing if a medication called methylphenidate can help children and teenagers with KBG syndrome who have attention and ADHD-related challenges.

  Recruiting Phase 4 Radboud University Medical Center · Nijmegen, Gelderland · NCT06465641

• Comparing two surgical methods for cochlear implants

  This study is testing which of two surgical methods for cochlear implants helps adults with severe hearing loss keep their natural hearing and improves their overall sound experience.

  Recruiting Radboud University Medical Center · Nijmegen · NCT06453343

• Examining the immune system in hereditary pheochromocytoma and paraganglioma

  This study is testing how the immune system works in people with pheochromocytoma and paraganglioma, especially those with a family history of these tumors, to see if it can help us find better treatments.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland · NCT06444607

• Investigating the effects of diet and therapy on endometriosis pain

  This study is testing whether an anti-inflammatory diet and therapy can help women with endometriosis feel less pain and improve their quality of life.

  Recruiting at 5 sites Radboud University Medical Center · 's-Hertogenbosch and 4 other locations · NCT06332560

• Understanding cognitive changes in children aged 7 to 10

  This study looks at how children's thinking skills change between ages 7 and 10 to see what makes them different and how these differences might affect them later in life.

  Recruiting Radboud University Medical Center · Nijmegen · NCT06330090

• Comparing MRI and Ultrasound for Evaluating Muscle Function in Facioscapulohumeral Dystrophy

  This study is testing whether ultrasound and MRI can help us understand how muscle function is affected in people with Facioscapulohumeral Dystrophy.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland · NCT06227182

• Focal therapy for men with prostate cancer

  This study is testing a new treatment called focal therapy for men with intermediate-risk prostate cancer to see if it can reduce side effects and improve their quality of life compared to traditional treatments.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland and 4 other locations · NCT06223295

• Effect of a vegetarian diet on immunity in heart attack patients and healthy volunteers

  This study is testing whether a vegetarian diet can improve immunity in people who have had a heart attack and their healthy partners.

  Recruiting Radboud University Medical Center · Nijmegen · NCT06209723

• Increasing physical activity in patients at risk of Parkinson's disease using a smartphone app

  This study is testing a smartphone app to help people at risk of Parkinson's disease increase their physical activity and exercise intensity over two years.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland · NCT06193252

• Understanding muscle fatigability in congenital myopathies

  This study is trying to understand how muscle fatigue affects people with congenital myopathies like Central Core Disease and Nemaline Myopathy over two years.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland and 1 other locations · NCT06157268

• Exploring how compensation strategies affect walking in Parkinson's disease

  This study tests different ways to help people with Parkinson's disease improve their walking by using a special app to see which methods work best for them.

  Recruiting Radboud University Medical Center · Nijmegen · NCT06142448

• Using PET/CT scans to improve follow-up care for stage III lung cancer patients

  This study is testing if using special PET/CT scans can help stage III lung cancer patients live longer and have better follow-up care compared to regular CT scans.

  Recruiting at 27 sites Radboud University Medical Center · Hilversum, Utrecht and 26 other locations · NCT06082492

• Understanding how breathing is controlled in people with Parkinson's disease

  This study is trying to understand how breathing is controlled in people with Parkinson's disease compared to healthy individuals to see if there are any differences.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland · NCT06074614

• Comparing high and standard doses of rifampicin for tuberculosis treatment

  This study is testing whether a higher dose of rifampicin can help people with pulmonary tuberculosis get better without causing more side effects compared to the standard lower doses.

  Recruiting at 2 sites Phase 3 Radboud University Medical Center · Turin and 1 other locations · NCT06057519

• Improving gut function in high-risk newborns through sensory stimulation

  This study is testing if a special sensory stimulation method can help preterm babies and those with a specific birth defect eat better and faster than those who only get regular care.

  Recruiting Radboud University Medical Center · Nijmegen · NCT06057415

• Validation of a new microscopic technique for diagnosing early-stage lung cancer

  This study is testing a new imaging technique to see if it can help doctors diagnose early-stage lung cancer more accurately and quickly during procedures.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland · NCT06007261

• Observational study on treatment effectiveness for Mycobacterium Avium Complex Pulmonary Disease

  This study is trying to see how well a three-drug treatment works for people newly diagnosed with Mycobacterium avium complex pulmonary disease and how well they stick to the treatment plan.

  Recruiting at 11 sites Radboud University Medical Center · Portland, Oregon and 10 other locations · NCT05906316

• Using antibiotics to prevent infections after esophageal surgery

  This study is testing whether using antibiotics to clean the digestive tract can help prevent infections after surgery for esophageal cancer.

  Recruiting at 2 sites Phase 3 Radboud University Medical Center · Leuven and 1 other locations · NCT05865743

• Observational study on young adults with ischemic stroke

  This study looks at young adults aged 18-50 who have had a stroke to see what causes it and how to better treat and prevent strokes in this age group.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland and 5 other locations · NCT05853796

• Program to reduce ICU agitation and use of physical restraints

  This study is testing a new program to help calm agitated adults in the ICU without using physical restraints, to see if it improves their care and reduces costs.

  Recruiting at 5 sites Radboud University Medical Center · Alkmaar and 4 other locations · NCT05783505

• Using advanced MRI to improve diagnosis of muscle-invasive bladder cancer

  This study is testing whether a new MRI method can improve the diagnosis of muscle-invasive bladder cancer compared to the standard procedure to see which one is better for patients.

  Recruiting at 15 sites Radboud University Medical Center · 's-Hertogenbosch and 18 other locations · NCT05779631

• Dendritic cell vaccination for ovarian cancer treatment

  This study is testing a special vaccine made from immune cells to see if it can help women with advanced ovarian cancer feel better while they receive chemotherapy.

  Recruiting Phase 1/2 Radboud University Medical Center · Nijmegen, Gelderland · NCT05773859

• Comparing GAG therapy to antibiotics for preventing recurrent urinary tract infections

  This study is testing whether a new bladder treatment using hyaluronic acid and chondroitin sulfate can help women with recurrent urinary tract infections just as well as antibiotics.

  Recruiting at 3 sites Phase 4 Radboud University Medical Center · Nijmegen, Gelderland and 2 other locations · NCT05652374

• Combining dutasteride with hormone therapy for salivary duct carcinoma

  This study is testing whether adding dutasteride to hormone therapy can help people with advanced salivary duct carcinoma feel better and live longer.

  Recruiting Phase 2 Radboud University Medical Center · Nijmegen, Gelderland · NCT05513365

• Using LSD to treat chronic cluster headaches

  This study is testing if taking a small dose of LSD every three days can help people with chronic cluster headaches feel better and have fewer headaches.

  Recruiting at 2 sites Phase 2 Radboud University Medical Center · Leiden and 1 other locations · NCT05477459

• Minimally invasive surgery for intracerebral hemorrhage

  This study is testing if early minimally invasive surgery can help people with brain bleeding feel better when done within 8 hours of their symptoms starting.

  Recruiting at 8 sites Radboud University Medical Center · Amsterdam and 10 other locations · NCT05460793

• Improving physical performance in older hospitalized patients through personalized nutrition and exercise

  This study is testing if personalized nutrition and exercise can help older patients in the hospital improve their physical performance and stay active after they go home.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland · NCT05413616

• Observational study on bone and soft tissue sarcoma in the Netherlands

  This study is collecting health information and experiences from people in the Netherlands who have bone or soft tissue sarcoma to help improve their treatment and care.

  Recruiting at 2 sites Radboud University Medical Center · Arnhem and 1 other locations · NCT05373810

• Personalized neck irradiation for head and neck cancer based on lymph node biopsy results

  This study is testing if using biopsy results to personalize neck radiation can help people with laryngeal and pharyngeal cancer avoid unnecessary treatment and improve their quality of life.

  Recruiting at 7 sites Phase 3 Radboud University Medical Center · Amsterdam and 8 other locations · NCT05333523

• Understanding genetic and pharmacokinetic factors in post-ERCP pancreatitis

  This study is trying to find out how genetic factors and how the body processes medications affect the risk of developing pancreatitis after a specific procedure called ERCP.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland · NCT05267379

• Using Hypertonic Saline Inhalation to Treat Mycobacterium Avium Complex Lung Disease

  This study tests if inhaling Hypertonic Saline along with regular care can help people with Mycobacterium avium complex lung disease feel better and improve their quality of life.

  Recruiting Phase 4 Radboud University Medical Center · Nijmegen · NCT05192057

• Smartphone app to boost exercise in Parkinson's patients

  This study tests if a smartphone app can help people with Parkinson's Disease exercise more and improve their fitness over a year.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland · NCT04848077

• Exercise to improve outcomes in colorectal cancer patients

  This study is testing whether aerobic and resistance exercise can help people with metastatic colorectal cancer feel better and handle chemotherapy without needing to change their treatment.

  Recruiting at 13 sites Radboud University Medical Center · 's-Hertogenbosch and 12 other locations · NCT04754672

• Analyzing neuroinflammatory markers in cerebrospinal fluid before and after thoracic aortic surgery

  This study is trying to see how levels of certain proteins in the fluid around the brain change before and after thoracic aortic surgery to better understand why some patients experience confusion or memory problems afterward.

  Recruiting Radboud University Medical Center · Nijmegen · NCT04523909

• Optimizing hormonal therapy for advanced and recurrent endometrial cancer

  This study is trying to find better ways to use hormonal therapy for women with advanced or recurring endometrial cancer by looking at their tumor samples to see who might benefit most from this treatment.

  Recruiting Radboud University Medical Center · Nijmegen · NCT03621904

• Understanding long-term effects of ICU care on patients

  This study looks at the long-term effects of ICU treatment on patients to see how it impacts their physical and mental health over several years.

  Recruiting Radboud University Medical Center · Nijmegen · NCT03246334

• Understanding how drugs pass through the placenta during pregnancy

  This study is trying to see how well different medications can cross the placenta during pregnancy to help doctors figure out the best dosages for pregnant women and understand how these drugs might affect their babies.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland · NCT02438631

• Using cine MRI to detect abdominal adhesions

  This study is testing if a special type of MRI can help find and map abdominal adhesions in patients who have had previous surgeries, to make future operations safer.

  Recruiting Radboud University Medical Center · Arnhem, Gelderland and 4 other locations · NCT00882167

• Understanding how HIV medications work in pregnant women

  This study is testing how HIV medications work in pregnant women during the third trimester to see if we can improve their treatment.

  Recruiting at 16 sites Radboud University Medical Center · Brussels and 20 other locations · NCT00825929

Quick answers

How many clinical trials run by Radboud University Medical Center are recruiting right now?

64, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in Netherlands (64 trials), Belgium (3 trials), Italy (2 trials), Germany (2 trials), Spain (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 4, Phase 4: 4, Phase 2: 3, Phase 2/3: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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