Using cine MRI to detect abdominal adhesions
Sensitivity and Predictive Value of Functional Cine Magnetic Resonance Imaging (MRI) Detecting Intra-abdominal Adhesions
This study is testing if a special type of MRI can help find and map abdominal adhesions in patients who have had previous surgeries, to make future operations safer.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Radboud University Medical Center Academic / other |
| Locations | 5 sites (Arnhem, Gelderland and 4 other locations) |
| Trial ID | NCT00882167 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the sensitivity and specificity of functional cine magnetic resonance imaging (MRI) in detecting and mapping intra-abdominal adhesions in patients who have undergone previous abdominal surgeries. By utilizing cineMRI, the study seeks to provide a non-invasive imaging technique that could help identify adhesions that may lead to complications during reoperations. The study will involve multiple centers and focus on patients with significant abdominal scarring. The primary outcome will measure how accurately cineMRI can detect adhesions compared to existing methods.
Who should consider this trial
Good fit: Ideal candidates are patients with a median abdominal scar from prior open abdominal surgeries measuring at least 10 cm.
Not a fit: Patients with severe claustrophobia or those for whom MRI is contraindicated will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved imaging techniques that help prevent complications related to abdominal adhesions during surgeries.
How similar studies have performed: While the approach of using cineMRI for this purpose is novel, other imaging techniques have shown varying degrees of success in detecting adhesions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with a median abdominal scar due to a previous open abdominal surgical procedures with a length of at least 10 cm and have given written consent. Exclusion Criteria: * Severe claustrophobia. * No MRI allowed
Where this trial is running
Arnhem, Gelderland and 4 other locations
- Rijnstate Hospital — Arnhem, Gelderland, Netherlands (Not_yet_recruiting)
- Radboud University Nijmegen Medical Center — Nijmegen, Gelderland, Netherlands (Recruiting)
- Jeroen Bosch Hospital — 's-Hertogenbosch, Netherlands (Not_yet_recruiting)
- Gelre Hospital — Apeldoorn, Netherlands (Not_yet_recruiting)
- Catharina Hospital — Eindhoven, Netherlands (Not_yet_recruiting)
Study contacts
- Principal investigator: Richard PG ten Broek — Radboud University Nijmegen Medical Center
- Study coordinator: Richard ten Broek
- Email: r.tenbroek@chir.umcn.nl
- Phone: +31243619493
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.