Exploring how compensation strategies affect walking in Parkinson's disease
Unravelling the Neural Mechanisms Underlying Compensation Strategies for Gait Impairments in Parkinson's Disease: a Transnational, Multimodal Approach
NA · Radboud University Medical Center · NCT06142448
This study tests different ways to help people with Parkinson's disease improve their walking by using a special app to see which methods work best for them.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 384 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Radboud University Medical Center (other) |
| Locations | 1 site (Nijmegen) |
| Trial ID | NCT06142448 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of various compensation strategies on gait impairment in individuals with Parkinson's disease. It focuses on understanding how different cueing methods, both external and internal, can help patients improve their walking abilities. The research aims to identify which strategies are most effective for different patients, acknowledging that responses to these cues can vary significantly. By utilizing a cueing app, the study seeks to personalize treatment approaches for better outcomes in gait rehabilitation.
Who should consider this trial
Good fit: Ideal candidates include men and women over 18 years old diagnosed with idiopathic Parkinson's disease who can provide informed consent.
Not a fit: Patients who have been using compensation strategies daily for the past month or have severe co-morbidities limiting their ability to walk may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more effective, personalized rehabilitation strategies for improving walking in patients with Parkinson's disease.
How similar studies have performed: Previous studies have shown varying success with cueing strategies in Parkinson's disease, but this approach aims to provide a more tailored understanding, making it a novel exploration.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Men and women of age \> 18 years with idiopathic Parkinson's disease; * Written informed consent. Exclusion Criteria: * Daily usage of compensation strategies for the past month; * Presence of deep brain stimulation (DBS); * Presence of severe co-morbidity limiting ambulation (e.g. stroke, orthopaedic problems); * Inability to walk unaided (with the exception of a customary cane); * Inability to walk for \> 3 minutes consecutively; * Severe auditory impairments, hampering perception of auditory cues; * Severe cognitive impairment (MMSE \< 21)
Where this trial is running
Nijmegen
- Radboudumc — Nijmegen, Netherlands (RECRUITING)
Study contacts
- Study coordinator: Cindel Albers
- Email: cindel.albers@radboudumc.nl
- Phone: (024) 366 84 26
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Parkinson Disease, Rehabilitation, Gait Impairment, Personalized treatment, Compensation strategies