Personalized lifestyle support with an app for adults seeing their GP for depression symptoms

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults presenting to general practice with depressive symptoms are randomized by clinic to receive either usual care or usual care plus a personalized lifestyle intervention delivered via a smartphone app. App users complete a questionnaire covering six themes (mental wellbeing, substance use, social relationships, healthy eating, sleep, and physical activity), set personal goals, and receive tailored guidance and self-monitoring prompts. Outcomes include changes in depression symptoms over time and cost-effectiveness compared with usual care alone. The trial is conducted in multiple Dutch academic centers and embedded in routine primary-care settings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Currently experiencing an episode of symptoms of depression and receiving treatment for this episode from their GP or GP-MHW for less than six months
* Have a smartphone
* Be proficient in Dutch

Exclusion Criteria:

* Severe mental illness (such as psychosis or bipolar disorder)
* Severe alcohol or drug addiction requiring specialized secondary care
* High suicide risk
* moderate to severe cognitive impairment (as determined by the GP)

Patients who visit their GP for depressive symptoms but with a PHQ-9 of \<5 at baseline are allowed to use the PLI, but will not be included in the primary analysis.

Where it's running

• Radboudumc
  Nijmegen, Gelderland, Netherlands Recruiting
• Amsterdam UMC
  Amsterdam, North Holland, Netherlands Recruiting
• UMC Groningen
  Groningen, Provincie Groningen, Netherlands Recruiting

Study contacts

• Study coordinator: Eline Jagtenberg
• Email: eline.jagtenberg@radboudumc.nl
• Phone: 0652902132

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.