Sponsor or institution
Clinical trials and research at Northwestern University at Chicago
As of November 12, 2026, Find a Trial lists 648 NIH-funded research projects at this institution, with $368.3 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 648NIH research projects
NIH-funded research (newest 40 of 648)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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High-intensity exercise as a treatment for Parkinson's disease
This study is looking at whether doing high-intensity endurance exercise can help people who have just been diagnosed with Parkinson's disease feel better and slow down their symptoms, especially since current medications don't always do the trick.
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Software to quickly assess organ dose after radionuclide exposure
This study is creating a helpful software tool that quickly calculates how much radiation your organs absorb after you've taken certain radioactive substances, so you can get better care and treatment based on your individual needs.
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Investigating innovative approaches to improve health outcomes.
This study is looking for better ways to improve your care and treatment, so you can get more personalized options that work best for you.
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Investigating innovative approaches to improve health outcomes.
This study is looking for new ways to improve care and treatment for patients, and if you join, you might help test some exciting new methods that could lead to better health for everyone.
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Investigating innovative approaches to improve health outcomes.
This study is looking for ways to improve care and treatment for patients like you, by trying out new methods that could help manage your health better.
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Investigating core biological processes
This study is all about exploring important biological processes that affect our health, and it invites patients to help discover new ways to improve care for everyone.
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A core administrative project at Northwestern University.
This study is all about making research at Northwestern University run more smoothly, which could help future studies and ultimately benefit patients like you.
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Understanding how cells manage improperly folded proteins
This study is looking at how cells help proteins fold correctly, especially in a part of the cell called the endoplasmic reticulum, and it aims to understand how problems with this process might be connected to diseases like Alzheimer's, using advanced tools to learn more about how our cells stay healthy.
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Understanding how the brain controls eye movements during dreaming
This study is looking at how a part of the brain helps control eye movements while we dream, which could help us understand how our brains create and experience dreams, especially for people with certain mental health conditions.
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Participation in advanced cancer clinical trials at Northwestern University
This study is all about helping advanced cancer patients at Northwestern University find and join clinical trials that could offer them new treatment options and better care.
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Improving depression treatment for African American adults with high blood pressure
This study is looking to help African American adults in Chicago who are dealing with both depression and high blood pressure by creating a treatment that fits their community's needs and seeing how well it works for improving their mental health and blood pressure.
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Examining racial differences in pain medication prescriptions after hip and knee surgeries
This study is looking into whether older Black Americans get less pain relief medication than White Americans after hip and knee surgeries, with the goal of finding ways to make sure everyone gets the care they need for pain management.
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Measuring physical activity in toddlers
This study is looking at how little kids under 2 years old develop their habits for being active, and it’s creating a new tool to better track their movement so we can learn how to help them stay healthy and active from a young age.
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Improving HIV care access and viral suppression for patients with complex needs
This study is looking to make HIV care easier and more supportive for people who face challenges like stigma, poverty, and mental health issues, by introducing a new approach in clinics that helps them get the care they need to stay healthy.
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Investigating blood markers for early signs of cognitive decline and brain changes
This study is looking at how changes in tiny pieces of DNA found in your blood might help spot early signs of memory problems and brain changes linked to Alzheimer's disease, so that people can get help sooner.
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Reducing CMV reactivation in kidney transplant patients
This study is looking at ways to stop the cytomegalovirus from coming back in people who have had a kidney transplant, by understanding how certain injuries during the transplant process can trigger the virus, and it aims to find new treatments that can help improve kidney health and reduce infections.
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Investigating CALHM channels in the nervous system
This study is looking at how certain channels in our nervous system help with important functions like taste and hearing, and how problems with these channels might be linked to conditions like Alzheimer's and depression, with the hope of finding new ways to help treat these issues.
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Exploring how specific brain neurons influence reward-seeking behavior and decision-making
This study is looking at how certain brain cells help us understand rewards and punishments, especially in people who struggle with cocaine use, to find out what drives their cravings and behaviors.
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Understanding how Pannexin channels work in the nervous system
This study is looking at special channels in the nervous system that help send signals and release energy, with the hope of finding new ways to treat conditions like inflammation and nerve protection.
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Investigating cardiovascular health in young South Asian Americans
This study is looking at heart health in young South Asian Americans to find ways to help prevent heart disease early on, so we can create better health tips just for them.
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Detecting early syphilis using unique bacterial fragments
This study is looking at a new way to quickly and accurately detect syphilis by using tiny pieces of the bacteria that cause it, which could help people get treated faster than with current tests.
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Creating a user-friendly tool for assessing early childhood development
This study is working on a new, easy-to-use tool that helps check how babies and toddlers grow and develop in areas like thinking, talking, and moving, so parents and doctors can better understand and support their little ones.
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Understanding blood sugar levels during pregnancy and their effects on outcomes
This study is looking at how using continuous glucose monitors can help pregnant women, especially those at risk for gestational diabetes, by tracking their blood sugar levels to spot any changes early on and improve health for both moms and babies.
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Understanding how PlexinB2 affects tumor cell clusters in cancer
This study is looking at how a protein called PlexinB2 affects the way tumor cells from triple-negative breast cancer interact with the immune system, with the hope of finding new ways to stop cancer from spreading and improve treatment options for patients.
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Understanding how tumor environments affect T cell behavior
This study is looking at how the area around tumors affects T cells, which are important for fighting cancer, to help find new ways to boost their ability to attack colorectal cancer.
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Understanding different types of heart failure to improve treatment options
This study is looking at different types of heart failure with preserved ejection fraction (HFpEF) to better understand the condition and find more effective treatments, and it's inviting patients to participate by sharing their health information and experiences.
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Enhancing cancer treatment using natural killer cells in dogs with soft tissue sarcoma
This study is looking at a new way to help treat soft tissue sarcoma in dogs by using special immune cells called natural killer cells, along with a targeted antibody, to make the treatment more effective and hopefully improve outcomes for our furry friends.
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Impact of incarceration on health and dementia risk
This study looks at how being in prison might impact the health of Black and Hispanic adults and their chances of developing Alzheimer's and related memory issues, focusing on things like high blood pressure and depression, to find ways to improve health and reduce risks during middle age.
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Understanding how specific genes affect kidney cell development
This study is looking at how a specific signaling process in the kidney helps keep important cells healthy, which could lead to new treatments for kidney diseases.
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Investigating the 3D structure of proteins related to SARS-CoV-2 and other infectious diseases
This study is looking at the tiny structures of proteins related to COVID-19 and other infectious diseases to help find better treatments and vaccines, which could ultimately benefit patients like you.
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Investigating the 3D structures of proteins from infectious diseases
This study is looking at the shapes of certain proteins linked to infectious diseases to help scientists understand how these germs work, which could lead to better treatments or vaccines for patients.
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Understanding the 3D structures of proteins related to antibiotic resistance
This study is looking at the shapes of proteins from germs that cause infections to help find better ways to treat illnesses, especially those caused by bacteria that don't respond to regular antibiotics, so patients can have more effective options for getting better.
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Investigating the 3D structures of proteins from infectious diseases like coronaviruses
This study is looking at the tiny structures of proteins from different infectious diseases, like coronaviruses, to help us understand how these germs work, which could lead to new ways to fight them.
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Developing a universal vaccine for influenza
This study is looking at the shapes of certain proteins linked to the flu to help create a better vaccine that could protect you from different strains of the virus, making it easier for everyone to stay healthy during flu season.
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How sugar changes in the immune system affect aging and HIV infection.
This study is looking at how changes in sugar molecules on antibodies might affect inflammation and aging in people with HIV who are on treatment, with the goal of finding new ways to help manage their health and reduce related issues.
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Understanding how a component of Lyme disease bacteria affects symptoms
This study is looking at how a part of the Lyme disease bacteria might cause ongoing symptoms, like arthritis, in people even after they've been treated with antibiotics, and it aims to help us understand why some patients still feel unwell.
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Understanding how certain kidney cells contribute to severe kidney disease in African Americans
This study is looking at how certain kidney cells that don’t heal properly after injury can cause more problems for people, especially African Americans who are more likely to develop serious kidney disease, and it aims to understand how a specific gene might help these cells repair themselves better.
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Investigating how a protein linked to Parkinson's disease affects brain immune cells and their function
This study is looking at how a protein linked to Parkinson's disease affects brain immune cells, using cells from patients with known genetic changes to see how these changes impact the cells' ability to handle waste and respond to inflammation.
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Using technology to help breast and endometrial cancer survivors increase their physical activity
This study is looking at how using smartphone apps and fitness trackers can help breast and endometrial cancer survivors get more active and stay healthy by providing personalized support and tracking their progress.
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Investigating how certain proteins affect memory formation in the brain.
This study is looking at how certain brain processes help us remember things better, especially in people with memory issues like Alzheimer's, to find new ways to improve memory and create better treatments.
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