NIH-funded research U01 cooperative agreement

Understanding blood sugar levels during pregnancy and their effects on outcomes

Official title: Glycemic Profiles and Pregnancy Outcomes Study (GLOSS)

Funded at Northwestern University at Chicago · NIH-11167411 · Data updated 2026-11-12

This study is looking at how using continuous glucose monitors can help pregnant women, especially those at risk for gestational diabetes, by tracking their blood sugar levels to spot any changes early on and improve health for both moms and babies.

More Pregnancy research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionNorthwestern University at Chicago
NIH-funded
Lab location1 site (Chicago, United States)
Project startSeptember 20, 2019
Project endJuly 31, 2025
Funding year2024
Award (this year)$44,539
NIH project number3U01DK123745-05S1
Project IDNIH-11167411 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include pregnant women, particularly those in their first trimester or at risk for developing gestational diabetes.

Less likely to help

Patients who are not pregnant or those who do not have risk factors for gestational diabetes may not benefit from this research.

What this research studies

This research investigates how continuous glucose monitoring (CGM) can provide insights into blood sugar levels in pregnant women, particularly those at risk for gestational diabetes mellitus (GDM). By tracking glucose levels throughout pregnancy, the study aims to identify patterns and changes that could help in diagnosing and managing GDM earlier, potentially improving outcomes for both mothers and their children. The approach involves collecting and analyzing data from CGM devices to understand the relationship between glycemic profiles and pregnancy outcomes.

Why it matters

Potential benefit: If successful, this research could lead to earlier diagnosis and better management of gestational diabetes, reducing risks for mothers and their babies.

How similar studies have gone: Other research has shown promise in using continuous glucose monitoring for managing diabetes, suggesting that this approach could be beneficial in the context of pregnancy as well.

Where this research is happening

  • Northwestern University at Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Yee, Lynn M — Northwestern University at Chicago
  • Study coordinator: Yee, Lynn M

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.