NIH-funded research NIH-funded research

Understanding how the brain controls eye movements during dreaming

Official title: Role of the Superior Colliculus in Orienting Eye Movements during REM Sleep

Funded at Northwestern University at Chicago · NIH-11260638 · Data updated 2026-11-12

This study is looking at how a part of the brain helps control eye movements while we dream, which could help us understand how our brains create and experience dreams, especially for people with certain mental health conditions.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNorthwestern University at Chicago
NIH-funded
Lab location1 site (Chicago, United States)
Project startApril 1, 2025
Project endMarch 31, 2028
Funding year2025
Award (this year)$249,000
NIH project number4R00EY033850-03
Project IDNIH-11260638 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research would include individuals experiencing sleep disturbances or psychiatric conditions that may be related to dreaming.

Less likely to help

Patients who do not experience REM sleep or have no psychiatric conditions related to dreaming may not benefit from this research.

What this research studies

This research investigates the role of the superior colliculus, a part of the brain, in controlling eye movements during REM sleep, which is the sleep phase associated with vivid dreaming. By examining the activity of specific brain cells during this phase, the study aims to uncover how our brain generates and interacts with visual experiences while we dream. The researchers will focus on rapid eye movements as indicators of how the brain processes these dream experiences, potentially linking them to psychiatric conditions. This work could provide insights into the neurophysiological mechanisms underlying our perception of reality and dreams.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of sleep and dreaming, potentially leading to better treatments for psychiatric disorders linked to abnormal dream experiences.

How similar studies have gone: While the specific approach of linking eye movements during REM sleep to brain activity is novel, related research has shown promising results in understanding sleep and its effects on mental health.

Where this research is happening

  • Northwestern University at Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Senzai, Yuta — Northwestern University at Chicago
  • Study coordinator: Senzai, Yuta

Related research

Other NIH-funded projects on the same topics.

  • High-intensity exercise as a treatment for Parkinson's disease

    This study is looking at whether doing high-intensity endurance exercise can help people who have just been diagnosed with Parkinson's disease feel better and slow down their symptoms, especially since current medications don't always do the trick.

    NIH research Northwestern University at Chicago · Chicago, United States · NIH-11290686

  • Software to quickly assess organ dose after radionuclide exposure

    This study is creating a helpful software tool that quickly calculates how much radiation your organs absorb after you've taken certain radioactive substances, so you can get better care and treatment based on your individual needs.

    NIH research Northwestern University at Chicago · Chicago, United States · NIH-11289682

  • Investigating innovative approaches to improve health outcomes.

    This study is looking for better ways to improve your care and treatment, so you can get more personalized options that work best for you.

    NIH research Northwestern University at Chicago · Chicago, United States · NIH-11289671

  • Investigating innovative approaches to improve health outcomes.

    This study is looking for new ways to improve care and treatment for patients, and if you join, you might help test some exciting new methods that could lead to better health for everyone.

    NIH research Northwestern University at Chicago · Chicago, United States · NIH-11289670

  • Investigating innovative approaches to improve health outcomes.

    This study is looking for ways to improve care and treatment for patients like you, by trying out new methods that could help manage your health better.

    NIH research Northwestern University at Chicago · Chicago, United States · NIH-11289669

  • Investigating core biological processes

    This study is all about exploring important biological processes that affect our health, and it invites patients to help discover new ways to improve care for everyone.

    NIH research Northwestern University at Chicago · Chicago, United States · NIH-11289668

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.