Sponsor or institution
Clinical trials and research at New York Genome Center
As of November 12, 2026, Find a Trial lists 34 NIH-funded research projects at this institution, with $35.8 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 34NIH research projects
NIH-funded research (34)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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New York Genome Center’s project on somatic mosaicism across human tissues
A nationwide effort to build a high-quality catalog of somatic genetic changes found in healthy tissues from people of diverse backgrounds, with the goal of better understanding aging and disease.
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Mapping genome control switches in immune cells to understand autoimmune diseases
A team will build a high-throughput toolbox to map how noncoding genome regions control gene activity in human immune cells to better understand autoimmune diseases and brittle diabetes.
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Scalable multi-ancestry genomics to uncover blood and heart disease mechanisms
A multi-ancestry study will explore how genetic differences influence blood traits and cardiovascular disease using scalable functional genomics tools.
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Predicting Psychosis Outcomes from Electronic Health Records
Researchers will use electronic health records to help predict how people with psychosis may fare over time and tailor care.
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ALS-FTSD: How brain regions and cells drive ALS and frontotemporal dementia together
A research grant to study how specific brain regions and cellular changes relate to ALS and related frontotemporal dementia symptoms in people who have the disease.
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Understanding genetic networks in autism and bipolar disorders to improve biology and treatment
A research grant will study how genetic factors influence autism and bipolar disorder by using advanced math and large genetic datasets to map networks in the brain.
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LTBR-enhanced CAR T-cell therapy for relapsed or refractory B‑cell lymphoma
The team will make CAR T-cells that carry LTBR to help people with relapsed or refractory diffuse large B‑cell lymphoma get stronger, longer-lasting responses.
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Mapping single- and double-strand DNA breaks and gene activity in individual tumor cells
Researchers will measure single- and double-strand DNA breaks alongside gene activity in individual cancer cells to help tailor DNA-damaging treatments to the right patients.
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Mapping molecular brain changes in ALS and frontotemporal dementia
This project uses detailed molecular and spatial mapping of brain tissue to connect specific brain changes with thinking, language, and behavior problems in people with ALS and frontotemporal dementia.
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NextGen Spatial Multi-omics Platform for Tissue Biology
A new, affordable platform will map multiple molecular layers in human and animal tissues to better understand how cells organize and communicate.
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Investigating genetic factors influencing heart, lung, blood, and sleep disorders.
This study is looking for people to help us understand how our genes might affect health issues like heart, lung, blood, and sleep problems, so we can find better ways to care for patients.
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Predicting Psychosis Outcomes from Health Records
This project uses artificial intelligence to help predict future outcomes for people living with psychosis, aiming for more personalized care.
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Protecting patient privacy while analyzing genetic data
This study is working on new ways for researchers to look at genetic information while keeping your personal details safe and private, so they can better understand health conditions without risking your confidentiality.
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Understanding Genetic Links to Heart Disease and Blood Traits
This project explores how our genes influence blood health and heart disease, looking at information from many different people.
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Finding DNA switches that control T cells and autoimmune risk
Using gene-editing and single-cell methods to find DNA 'switches' that change how T cells behave for people with autoimmune conditions like brittle diabetes.
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Creating detailed maps of human tissues and cells
This study is creating a detailed map of human tissues to help scientists understand how they work and connect, and it will also let researchers share their own data to work together better.
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Understanding genetic factors in mental disorders using advanced algorithms
This study is looking at the genes linked to conditions like autism and bipolar disorder to help us understand what makes them happen, which could lead to better treatments for people living with these challenges.
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Developing new technologies to analyze cell behavior and identity
This study is working on new tools to better understand how cells act and recognize themselves, which could help improve how we diagnose and treat diseases for patients like you.
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Developing new technologies to analyze cell behavior and identity
This study is all about finding new ways to look at how cells act and identify themselves, which could help us understand diseases better and improve treatments for patients like you.
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Developing new technologies to understand cell behavior and identity
This study is exploring new ways to look at how different molecules and environmental factors affect how cells behave, which could help us understand diseases better and lead to better tests and treatments for patients.
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Developing new technologies to analyze cell behavior and identity
This study is all about using new technology to learn how cells work and interact with their surroundings, which could help us find better treatments for diseases by understanding what's happening at the cellular level.
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Investigating social and genetic factors affecting breast cancer disparities
This study is looking into why Black patients, especially in West Africa, tend to have more aggressive breast cancer, and it aims to gather information from patients to help understand the social, environmental, and genetic reasons behind this issue.
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Improving CAR T-cell therapy for patients with relapsed lymphoma
This study is looking at how to make CAR T-cell therapy work better for people with tough-to-treat diffuse large B-cell lymphoma by exploring a special receptor in T-cells that might help them fight cancer more effectively.
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Understanding how cell states change over time with single-cell multiomics
Researchers will study how individual cells change their gene regulation over time, using advanced single-cell multiomics, to learn more about aging and cancer.
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Developing statistical methods to understand human tissue development and disease
This study is looking at how our genes and tissues change as we grow, using special samples from both humans and primates, to help us better understand developmental diseases and improve treatments for patients.
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Mapping genetic variants that affect immune system function
This study is looking at how certain genes affect the immune system, especially T cells, which are important in autoimmune diseases, to help us better understand what goes wrong in these conditions.
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Understanding genetic changes in healthy human tissues over time
This study is looking at how small changes in our DNA, called somatic mutations, happen in healthy tissues over time, and it needs volunteers to share tissue samples to help us learn more about how these changes might affect our health as we age or develop diseases like heart and brain disorders.
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Developing advanced technologies to analyze cell behavior and identity
This study is exploring new ways to look at how cells in our body work and interact with each other, which could help doctors find better ways to diagnose and treat diseases.
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Understanding disease mechanisms in ALS and frontotemporal dementia
This study is looking at brain tissue from people who had ALS and frontotemporal dementia to understand how changes in brain cells affect the symptoms they experienced, with the hope of finding new ways to diagnose and treat these conditions.
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Understanding genetic factors in blood traits and heart disease
This study is looking at how certain genes might affect heart disease and blood traits, using cutting-edge technology to help us understand these connections better, so we can find new ways to help people at risk for cardiovascular issues.
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Understanding the cellular interactions and molecular changes in ALS
This study is looking at how different brain and spinal cord cells interact in people with ALS to better understand the disease and find new ways to diagnose and treat it.
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Investigating how gene regulation changes in individual brain cells over time
This study is looking at how aging affects the way brain cells work and express their genes, which could help us understand neurodegenerative diseases better and lead to new treatments for patients.
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Using CRISPR technology to understand how different RNA forms function in cancer
This study is looking at how certain RNA molecules might play a role in cancer growth and why some treatments don't work, using a new method to carefully reduce these RNA levels in cancer cells to see what happens, all with the hope of finding better ways to fight cancer.
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Creating detailed maps of human tissues and cells
This study is creating a detailed map of human tissues to help scientists understand how they work, and it will also let researchers share their own data to collaborate better.
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