Developing statistical methods to understand human tissue development and disease
Statistical Methods for Characterizing Molecular Mechanisms of Human Tissue Development and Disease
['FUNDING_U01'] · NEW YORK GENOME CENTER · NIH-10990778
This study is looking at how our genes and tissues change as we grow, using special samples from both humans and primates, to help us better understand developmental diseases and improve treatments for patients.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NEW YORK GENOME CENTER (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10990778 on ClinicalTrials.gov |
What this research studies
This research focuses on creating advanced statistical methods to analyze complex data from human and non-human primate tissues. By utilizing unique biospecimens from the Developmental GTEx project, the team aims to uncover insights into how gene regulation and tissue structure change throughout different stages of life. The approach involves analyzing transcriptome variations and addressing challenges related to data complexity and sample size. Patients may benefit from improved understanding of developmental diseases and conditions through these innovative analytical techniques.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with developmental disorders or those interested in the genetic basis of tissue development.
Not a fit: Patients with conditions unrelated to tissue development or gene regulation may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better insights into developmental diseases, potentially improving diagnosis and treatment options for patients.
How similar studies have performed: Other research has shown success in using statistical methods to analyze complex biological data, indicating that this approach has potential for impactful findings.
Where this research is happening
NEW YORK, UNITED STATES
- NEW YORK GENOME CENTER — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LAPPALAINEN, TUULI — NEW YORK GENOME CENTER
- Study coordinator: LAPPALAINEN, TUULI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.