Investigating social and genetic factors affecting breast cancer disparities
Official title: SAMBAI - Social, Ancestry, Molecular Biology analyses of Inequities
Funded at New York Genome Center · NIH-11047347 · Data updated 2026-11-12
This study is looking into why Black patients, especially in West Africa, tend to have more aggressive breast cancer, and it aims to gather information from patients to help understand the social, environmental, and genetic reasons behind this issue.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York Genome Center NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | May 1, 2024 |
| Project end | April 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $258,643 |
| NIH project number | 1OT2CA297579-01 |
| Project ID | NIH-11047347 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation include Black patients, particularly those from West African nations, who are affected by breast cancer.
✕Less likely to help
Patients who do not identify as Black or are not affected by breast cancer may not receive direct benefits from this research.
What this research studies
This research focuses on understanding the reasons behind the higher rates of aggressive breast cancer in Black patients, particularly in West Africa. By analyzing social, environmental, genetic, and immunological factors, the study aims to uncover the underlying causes of these disparities. The SAMBAI team will collaborate with scientists from the US, Africa, and the UK to create a biobank and data repository that will facilitate comprehensive analyses of these factors. Patients may be involved in providing genetic and environmental data to help build a clearer picture of how these elements contribute to cancer outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for breast cancer in underserved populations.
How similar studies have gone: Previous research has shown success in understanding cancer disparities through genetic and environmental analyses, indicating that this approach has potential for impactful findings.
Where this research is happening
-
New York Genome Center
New York, United States Active
Researchers
- Principal investigator: Robine, Nicolas — New York Genome Center
- Study coordinator: Robine, Nicolas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.