Sponsor or institution
Clinical trials and research at Miami University Oxford
As of November 12, 2026, Find a Trial lists 40 NIH-funded research projects at this institution, with $14.4 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 40NIH research projects
NIH-funded research (40)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Nurse Practitioner Scope of Practice and Nursing Home Quality
This grant looks at how nurse practitioner regulatory rules affect staffing in nursing homes and the care residents receive.
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How X chromosome differences may influence alcohol drinking in mice
This project looks at how sex chromosomes, especially the X chromosome, might affect alcohol drinking behavior and related brain signals in mice, with the goal of informing human understanding and future therapies.
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ApoA4 and sympathetic signals to improve fat metabolism in obesity
A researcher team will study how apolipoprotein A4 (APOA4) affects fat tissue and liver metabolism through the body’s sympathetic nervous system, with a focus on adults with obesity.
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Understanding how the Grp94 protein helps keep cells healthy and how to target it safely
Researchers are studying the Grp94 protein to learn how it helps proteins fold correctly in cells, with implications for diabetes, cancer, heart, and brain diseases.
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Roadmap to unlock RPE plasticity for retinal regeneration
A research project aims to understand how retinal pigment epithelium (RPE) cells can be reprogrammed to become neural retina, with the goal of helping people with degenerative retinal diseases.
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Understanding how newt iris cells can become lens tissue to guide eye healing
Scientists are studying how a special kind of salamander-like newt can repair its eye lens by reprogramming iris cells, in the hope of finding new ways to treat human eye diseases.
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Lab-made ovarian implants to restore hormones and protect bone health in women
Testing whether implanting lab-grown ovarian tissue can restore hormone balance and reduce bone loss in women with menopause or ovarian failure.
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How the FOXE3 gene controls eye lens development
Researchers will use chick embryos to map the DNA switches that turn the FOXE3 gene on in the eye lens to help people born with missing or small lenses (aphakia or microphthalmia).
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Seeing membrane proteins inside cell-like membranes with advanced magnetic resonance
Using advanced pulsed EPR methods to reveal the shapes and motions of proteins in cell membranes that matter for heart disease and cancer patients.
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How changing protein shapes affect cell health and antibiotic resistance
Researchers are looking at how the way proteins bend and move controls cell processes tied to cancers, some neurodegenerative conditions, and bacterial resistance to antibiotics.
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Understanding how caregivers at home affect older adults' health visits and outcomes
A study will look at how including family, friends, and aides in older adults’ medical appointments may improve health and quality of life for both patients and caregivers.
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Creating realistic models to improve optical imaging techniques for early disease detection
This study is working on creating special models that mimic real body tissues to help improve a type of eye scan called optical coherence tomography (OCT), which can catch early signs of conditions like glaucoma, so patients can get better and earlier treatment.
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How sex chromosomes affect alcohol drinking
This research looks at whether having one versus two X chromosomes changes alcohol drinking and relapse, which could help explain why men and women experience alcohol problems differently.
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Understanding the Grp94 Chaperone for Disease Treatment
This project aims to understand how a protein called Grp94 works inside our cells, which could help develop new treatments for diseases like diabetes, cancer, and heart conditions.
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Exploring how retinal pigment epithelium cells can regenerate retinal neurons
This study is looking at how certain eye cells might be able to help repair damaged nerve cells in the retina, which could lead to new treatments for people with vision loss from retinal diseases.
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Understanding how newts regenerate their eye lenses
This study is looking at how newts can heal their eye lenses after getting hurt, and it aims to find out how these amazing creatures do it so we can someday help people with eye problems too.
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Using engineered ovarian tissue to help treat osteoporosis in women
This study is exploring a new way to help women after menopause by using specially created ovarian tissues to balance hormones that support bone health, which could lower the chances of osteoporosis and fractures, offering a safer option than traditional hormone treatments.
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How fitness and body fat affect recovery from low physical activity
This study is looking at how your fitness level and body fat can affect how well you bounce back from high blood sugar and blood vessel issues after not being active for a while, and it's for anyone interested in understanding their health better.
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How Deaf and Hearing Parents Help Their Autistic Children Focus
This study looks at how Deaf and hearing parents get their autistic kids to pay attention and interact, hoping to find the best ways to help improve communication skills for these children.
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Understanding how a specific gene regulates eye development using chicken embryos
This study is looking at how a specific gene called FOXE3 helps develop the eye lens in chicken embryos, which could help us understand conditions like aphakia, where babies are born without a lens, and lead to better treatments for eye problems.
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Investigating the structure and dynamics of membrane proteins using advanced spectroscopy techniques.
This study is all about learning how important proteins in our cell membranes work, using special techniques to get a clearer picture of them in a setting that mimics real cell membranes, so we can better understand their roles in our bodies.
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Investigating how protein structures affect their functions and roles in diseases.
This study is looking at how proteins change shape and how those changes can affect their roles in our bodies, especially in relation to antibiotic resistance and diseases like cancer and neurodegenerative disorders, to help us understand why proteins sometimes misfold and how that impacts our health.
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Using cancer cell metabolism to enhance immunotherapy effectiveness
This study is exploring a new way to help cancer patients by using the unique way cancer cells process drugs to create treatments that boost the immune system and fight tumors while protecting healthy cells.
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Understanding how a specific protein helps cells survive and function properly
This study is looking at a protein called Grp94 that helps other proteins fold correctly in our cells, which is important because when proteins don’t fold right, it can lead to serious health problems like diabetes and cancer, and the researchers hope their findings will help create better treatments for these conditio
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How certain brain cells affect opioid use and withdrawal behaviors
This study is looking at how certain brain cells affect behaviors related to opioid use disorder, helping us understand how they might influence both the pleasure of using opioids and the discomfort of withdrawal, which could lead to better treatment options for people struggling with addiction.
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Understanding how Mycoplasma pneumoniae bacteria affect chronic respiratory diseases.
This study is looking at how a type of bacteria called Mycoplasma pneumoniae behaves when it forms clusters, which might help us understand why it can cause long-lasting lung problems like pneumonia and asthma, and the researchers hope to find new ways to help people feel better.
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How early life inactivity affects muscle quality in adulthood
This study looks at how not being active as a child can affect muscle health and overall well-being later in life, using mice to help us understand the long-term effects of early inactivity on things like muscle strength and aging.
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How sex chromosomes affect alcohol drinking behaviors
This study looks at how being male or female might change the way animals drink alcohol, focusing on the role of their genes, especially those linked to the X chromosome, to help us understand why men and women might drink differently.
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Investigating polymer-lipid particles using advanced magnetic resonance techniques
This study is looking at tiny particles made of polymers and lipids to better understand how certain proteins in our cells work, which could help improve treatments for health issues, including those related to viral infections.
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Understanding how a protein affects B cell development and antibody production
This study is looking at how a protein called FCRL1 helps B cells, which are important for making antibodies to fight infections and respond to vaccines, work better, and it could lead to ways to boost our immune responses in different illnesses.
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How estrogen may protect against colorectal cancer in obese individuals
This study is looking at how obesity and estrogen might work together to affect the risk of developing colorectal cancer, and it's for anyone interested in understanding how these factors could help in finding new ways to prevent this type of cancer.
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Understanding how inflammation helps newts regenerate their eye lenses
This study is looking at how newts can regrow their eye lenses and what happens in their bodies during this process, with the hope that it can help improve treatments for people who have had cataract surgery.
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Improving imaging techniques for deep tissue analysis
This study is working on a new way to take clearer pictures of deep skin tissues, like those affected by burn injuries, using advanced technology to help doctors diagnose and treat these conditions better.
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Finding the source of heart rhythm problems using advanced ECG technology
This study is working on a new way to quickly find out where abnormal heart rhythms come from using a regular heart test, which could help doctors treat patients more effectively without needing invasive procedures.
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Investigating membrane proteins using advanced imaging techniques
This study is looking at how certain proteins in our cells are built, which is important for creating better medicines to fight viruses, and it's designed for anyone interested in how we can improve treatments for viral infections.
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Understanding how brain networks control rhythmic behaviors like breathing and swallowing
This study looks at how certain brain networks help control important actions like breathing and swallowing, using tiny creatures to learn how these networks adapt to changes around them, which could help improve health and daily life for people with neurological issues or those recovering from a stroke.
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Finding new drugs to combat antibiotic resistance using machine learning
This study is looking for new ways to stop certain bacteria from resisting antibiotics, which can make infections harder to treat, especially in COVID-19 patients, by testing over a million different compounds to find the best ones that can help.
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Improving communication skills in adolescents with developmental disabilities
This study is looking to improve how we understand and support social communication skills in teenagers who might struggle with communication due to developmental disabilities, by creating personalized assessments and interventions that really fit their needs.
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Investigating how Tsc1 affects neuron activity and brain function related to autism
This study is looking at how a gene related to autism affects certain brain cells in mice, hoping to learn more about how these changes might relate to behaviors seen in autism, which could eventually help find new ways to support people with the condition.
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Understanding how heart cells interact with their surrounding environment during heart development
This study is looking at how heart cells interact with their surrounding environment while the heart is developing, using zebrafish to learn how these interactions might help prevent heart problems that can happen from birth.
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