Creating realistic models to improve optical imaging techniques for early disease detection
Official title: Fabrication of solid and long-lasting phantoms for calibrating parametric OCT imaging
Funded at Miami University Oxford · NIH-11146045 · Data updated 2026-11-12
This study is working on creating special models that mimic real body tissues to help improve a type of eye scan called optical coherence tomography (OCT), which can catch early signs of conditions like glaucoma, so patients can get better and earlier treatment.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Miami University Oxford NIH-funded |
| Lab location | 1 site (Oxford, United States) |
| Project start | September 9, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $194,575 |
| NIH project number | 3R21EB033993-01A1S1 |
| Project ID | NIH-11146045 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals at risk for conditions like glaucoma who may benefit from improved diagnostic imaging techniques.
✕Less likely to help
Patients with conditions that do not involve optical imaging or those who are not at risk for diseases detectable by OCT may not receive benefits from this research.
What this research studies
This research focuses on enhancing optical coherence tomography (OCT), a medical imaging technique, by developing high-quality tissue phantoms that simulate real biological tissues. These phantoms will help in accurately measuring the optical attenuation coefficient (OAC), which is crucial for detecting early signs of diseases like glaucoma before any visible changes occur. The project involves fabricating and testing these phantoms to validate a new OCT technology called beam offset OCT (BS-OCT), which aims to improve diagnostic capabilities. By ensuring precise measurements, this research could lead to better early diagnosis and treatment options for patients.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of diseases, improving patient outcomes.
How similar studies have gone: Previous research has shown promise in improving imaging techniques through the use of phantoms, indicating that this approach could be effective.
Where this research is happening
-
Miami University Oxford
Oxford, United States Active
Researchers
- Principal investigator: Wang, Hui — Miami University Oxford
- Study coordinator: Wang, Hui
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.