Investigating membrane proteins using advanced imaging techniques
Official title: Polymer-Lipid Particles investigated by Magnetic Resonance Spectroscopy
Funded at Miami University Oxford · NIH-10579675 · Data updated 2026-11-12
This study is looking at how certain proteins in our cells are built, which is important for creating better medicines to fight viruses, and it's designed for anyone interested in how we can improve treatments for viral infections.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Miami University Oxford NIH-funded |
| Lab location | 1 site (Oxford, United States) |
| Project start | September 21, 2022 |
| Project end | August 31, 2025 |
| Funding year | 2022 |
| Award (this year) | $427,996 |
| NIH project number | 1R15GM144907-01A1 |
| Project ID | NIH-10579675 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals affected by viral infections that involve membrane proteins.
✕Less likely to help
Patients with conditions unrelated to membrane protein function or those not affected by viral infections may not benefit from this research.
What this research studies
This research focuses on understanding the structure of membrane proteins, which play a crucial role in various cellular functions and health. By utilizing polymer-lipid particles and magnetic resonance spectroscopy, the study aims to overcome challenges in determining the structures of these proteins, which are essential for developing effective antiviral therapies. The approach involves creating better lipid membrane mimetics that can accurately represent the natural environment of membrane proteins, facilitating more accurate structural analysis. This could lead to significant advancements in drug development targeting these proteins.
Why it matters
Potential benefit: If successful, this research could lead to the development of new antiviral therapies that effectively target membrane proteins involved in viral infections.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques to elucidate protein structures, indicating that this approach could yield valuable insights.
Where this research is happening
-
Miami University Oxford
Oxford, United States Active
Researchers
- Principal investigator: Konkolewicz, Dominik — Miami University Oxford
- Study coordinator: Konkolewicz, Dominik
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.