Finding the source of heart rhythm problems using advanced ECG technology
Official title: Development of an automatic real-time personalized non-invasive localization of the site of origin of the earliest ventricular activation
Funded at Miami University Oxford · NIH-10579726 · Data updated 2026-11-12
This study is working on a new way to quickly find out where abnormal heart rhythms come from using a regular heart test, which could help doctors treat patients more effectively without needing invasive procedures.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Miami University Oxford NIH-funded |
| Lab location | 1 site (Oxford, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $405,482 |
| NIH project number | 1R15HL167222-01 |
| Project ID | NIH-10579726 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals experiencing recurrent ventricular arrhythmias or those at high risk for sudden cardiac arrest.
✕Less likely to help
Patients with stable heart rhythms or those not experiencing arrhythmias may not benefit from this research.
What this research studies
This research focuses on developing a new method to quickly and accurately identify the origin of abnormal heart rhythms, known as ventricular arrhythmias, using a standard 12-lead electrocardiogram (ECG). By creating an automatic, real-time system, the goal is to help doctors pinpoint the exact location of these issues without invasive procedures. This could improve the effectiveness of treatments like catheter ablation and stereotactic body radiotherapy. Patients will benefit from a more precise diagnosis, leading to better-targeted therapies.
Why it matters
Potential benefit: If successful, this research could significantly enhance the diagnosis and treatment of life-threatening heart rhythm disorders, potentially reducing the risk of sudden cardiac arrest.
How similar studies have gone: Previous research has shown promise in using advanced ECG techniques for arrhythmia diagnosis, indicating that this approach could lead to significant advancements in patient care.
Where this research is happening
-
Miami University Oxford
Oxford, United States Active
Researchers
- Principal investigator: Zhou, Shijie — Miami University Oxford
- Study coordinator: Zhou, Shijie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.