How sex chromosomes affect alcohol drinking behaviors
Official title: Sex chromosome contributions to alcohol drinking behaviors
Funded at Miami University Oxford · NIH-10855841 · Data updated 2026-11-12
This study looks at how being male or female might change the way animals drink alcohol, focusing on the role of their genes, especially those linked to the X chromosome, to help us understand why men and women might drink differently.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Miami University Oxford NIH-funded |
| Lab location | 1 site (Oxford, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $321,102 |
| NIH project number | 1R01AA031463-01 |
| Project ID | NIH-10855841 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with a history of alcohol use or those interested in understanding the genetic factors influencing alcohol consumption.
✕Less likely to help
Patients who do not have a history of alcohol use or are not interested in the genetic aspects of alcohol consumption may not benefit from this research.
What this research studies
This research investigates the differences in alcohol consumption between male and female subjects, focusing on how sex chromosomes influence these behaviors. The study will use animal models to explore the effects of having two X chromosomes compared to one on alcohol intake. It aims to understand how prior alcohol exposure and genetic factors related to the X chromosome affect drinking behaviors and gene expression in the brain. By examining these interactions, the research seeks to uncover the biological mechanisms that contribute to varying alcohol consumption patterns between sexes.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment strategies for alcohol use disorders, particularly tailored to gender differences.
How similar studies have gone: Previous research has shown that sex differences significantly impact alcohol consumption behaviors, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Miami University Oxford
Oxford, United States Active
Researchers
- Principal investigator: Radke, Anna Kay — Miami University Oxford
- Study coordinator: Radke, Anna Kay
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.