Sponsor or institution

Clinical trials and research at Fred Hutchinson Cancer Center

• 64Clinical trials
• 663NIH research projects
• 5Countries

Newest trials

All recruiting trials (64)

• Telehealth pharmacist-led opioid education for cancer patients

  This pilot tests a telehealth group education session led by a palliative care pharmacist to help adults with cancer use opioids more safely and effectively.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT07737314

• Feasibility of using SmartMatch for guiding treatment options in rare gynecologic cancers

  This observational study tests whether SmartMatch analysis on tissue from standard surgeries or biopsies can help identify treatment options for adults with advanced rare gynecologic cancers.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT07731880

• Enfortumab Vedotin, Pembrolizumab, and Quemliclustat for unresectable or metastatic urothelial cancer

  This trial tests a three-drug combination to see if it can safely treat unresectable or metastatic urothelial cancer in adults.

  Recruiting Phase 1/2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT07667335

• WT1-targeted TCR T cells with azacitidine for AML with minimal residual disease

  This phase 1 trial tests whether giving a patient’s own WT1-specific T cells together with azacitidine is safe and can help treat AML with MRD positivity.

  Recruiting Phase 1 Fred Hutchinson Cancer Center · Seattle, Washington · NCT07645469

• Two-probe thermal ablation for cervical precancer in WLWH in South Africa

  This study tests whether using two probes for thermal ablation is safer or more effective than one probe for treating cervical precancer in women living with HIV in South Africa.

  Recruiting Fred Hutchinson Cancer Center · Durban · NCT07645378

• Two-probe thermal ablation for cervical precancer in WLWH in Zimbabwe

  This study tests whether using two TA probes (endocervical and ectocervical) is better than one probe for treating cervical precancer in women living with HIV in Zimbabwe.

  Recruiting Fred Hutchinson Cancer Center · Harare · NCT07645352

• Lung Toolkit: a tailored education program to help AI/AN cigarette smokers learn about lung cancer and screening

  A Lung Toolkit education program is tested to see if it improves knowledge about lung cancer and screening among American Indian and Alaska Native cigarette smokers aged 50–80.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT07615764

• Post-transplant dental cleaning to prevent chronic graft-versus-host disease

  This will try a dental cleaning about 28 days after an allogeneic stem cell transplant to see if it lowers the chance of chronic graft-versus-host disease in adult transplant recipients.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT07535008

• Eating with the clock: trying 8-hour eating windows during cancer treatment

  This study tests whether a time-restricted 8-hour eating window during adjuvant cancer therapy can improve treatment response and patient well-being for adults with solid tumors.

  Recruiting Fred Hutchinson Cancer Center · Los Angeles, California · NCT07524218

• Restorative Justice–Based Lung Cancer Screening Support for Black Individuals to See if Screening Increases Uptake

  This trial tests a restorative justice–based decision-making support to see if it increases lung cancer screening among Black adults who smoke or recently stopped.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT07490860

• Two-probe thermal ablation for cervical precancer in HIV+ women in Kenya

  This study tests whether using two probes for thermal ablation is more effective and acceptable than one probe for treating cervical precancer in women living with HIV in Kenya.

  Recruiting Fred Hutchinson Cancer Center · Nairobi · NCT07468695

• Estrogen-Plus-ARSI for Hormone-Sensitive Metastatic Prostate Cancer

  This phase 2 study tests whether adding transdermal estrogen to an androgen receptor signaling inhibitor improves quality of life for adults with newly diagnosed or recurrent metastatic hormone sensitive prostate cancer.

  Recruiting Phase 2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT07466498

• Two-probe thermal ablation for cervical precancer in WLWH in Rwanda

  This study tests whether using two probes for thermal ablation is safer or more effective than one probe for treating cervical precancer in women living with HIV in Rwanda.

  Recruiting Fred Hutchinson Cancer Center · Kigali · NCT07390916

• Adapted HOPE workshop to reduce burnout for gynecologic oncology clinicians

  This program will test whether an adapted HOPE workshop can help gynecologic oncology clinicians reduce stress and burnout.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT07282158

• Ruxolitinib given before, during, and after donor stem cell transplant for older adults with myelofibrosis or MDS/MPN overlap

  This phase II test tries whether giving ruxolitinib before, during, and after an allogeneic stem cell transplant helps older adults with myelofibrosis or MDS/MPN overlap have better transplant outcomes and fewer complications like graft-versus-host disease.

  Recruiting Phase 2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT07228624

• FH-FOLR1 CAR T cell therapy for advanced or recurrent osteosarcoma

  This trial will test whether FH-FOLR1 CAR T cells are safe and what dose works best in people aged 1–75 with advanced, recurrent, or treatment-resistant osteosarcoma.

  Recruiting Phase 1 Fred Hutchinson Cancer Center · Seattle, Washington · NCT07227571

• Pralatrexate and bendamustine with total‑body radiation before donor stem cell transplant for relapsed or refractory T‑cell lymphoma

  This trial tests whether giving pralatrexate and bendamustine together with total‑body radiation before a donor stem cell transplant helps adults with relapsed or refractory T‑cell non‑Hodgkin lymphoma.

  Recruiting Phase 1/2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT07225985

• Rifaximin versus no intervention for IgA MGUS

  This trial tests whether a short, two-week course of the antibiotic rifaximin can reduce precancerous IgA cells in adults with IgA MGUS.

  Recruiting Phase 2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT07209371

• Nemtabrutinib plus lisocabtagene maraleucel for relapsed or refractory CLL/SLL

  This will test whether adding the oral drug nemtabrutinib to lisocabtagene maraleucel (CAR T‑cell therapy) helps people with CLL/SLL that has come back or stopped responding to prior treatment.

  Recruiting Phase 2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT07194980

• Response-based lowering of linvoseltamab doses for relapsed or refractory multiple myeloma

  This trial tests whether lowering linvoseltamab doses for people with relapsed or refractory multiple myeloma can control the cancer while reducing side effects.

  Recruiting Phase 1/2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT07181941

• Tailored Patient Navigation to Boost Lung Cancer Screening in Tribal Communities

  This trial tests whether customized patient navigation can help American Indian and Alaska Native people in western Washington start and complete lung cancer screening.

  Recruiting at 2 sites Fred Hutchinson Cancer Center · Auburn, Washington and 1 other locations · NCT07176000

• Telephone coaching to help people with advanced cancer and their support person plan for end-of-life care

  This program tests whether two phone coaching sessions help people with advanced cancer and their support person have end-of-life conversations and complete advance directives.

  Recruiting at 3 sites Fred Hutchinson Cancer Center · Everett, Washington and 2 other locations · NCT07141407

• Choosing the Right Treatment Intensity for Adults with Acute Myeloid Leukemia and Myeloid Neoplasms

  This study tests whether a computer-guided randomization can help decide if a patient should receive higher- or lower-intensity chemotherapy when they’re not clearly fit, to see which approach is more helpful for adults with AML or related myeloid cancers.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT07094750

• Using a web tool (PACT) and patient navigation to improve goals-of-care conversations for hematopoietic cell transplant survivors

  This program tries the PACT website, a trained patient navigator, or both to help blood-cancer survivors who had a hematopoietic cell transplant have clearer advance care planning and goals-of-care conversations.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT07052630

• FLAG‑Ida chemotherapy followed by reduced‑intensity total‑body irradiation and donor stem cell transplant for adults 60+ with adverse‑risk AML or other high‑grade myeloid cancers

  This trial tests whether FLAG‑Ida chemotherapy given immediately before lower‑intensity total‑body radiation and a donor stem cell transplant can improve outcomes for adults 60 and older with newly diagnosed adverse‑risk acute myeloid leukemia or similar high‑grade myeloid cancers.

  Recruiting Phase 2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT07046078

• Axatilimab to treat skin thickening (sclerosis) from chronic graft‑versus‑host disease

  This trial tests whether axatilimab can improve or stop worsening skin thickening (sclerosis) in adults with chronic graft‑versus‑host disease after a donor stem cell transplant.

  Recruiting at 2 sites Phase 2 Fred Hutchinson Cancer Center · Tampa, Florida and 2 other locations · NCT07011810

• Helping colorectal cancer survivors keep up with post-surgery surveillance

  This project tests whether patient navigation services, an interactive web program called Current Together After Cancer (CTAC), or both help people with stage I–III colorectal cancer keep up with recommended post-surgery surveillance.

  Recruiting at 2 sites Fred Hutchinson Cancer Center · Seattle, Washington and 1 other locations · NCT06995924

• Boost immune activity and treatment response with guided interval bike exercise during immunotherapy

  We will test if a home-based, guided interval cycling program can boost immune activity and help people with non-small cell lung cancer tolerate and respond better to immunotherapy.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT06983899

• Improving HIV care engagement for cancer patients in Zimbabwe

  This study is trying to find ways to help people in Zimbabwe who have both HIV and cancer get better access to their HIV care while they are being treated for cancer.

  Recruiting Fred Hutchinson Cancer Center · Harare · NCT06934369

• Decitabine plus FLAG‑Ida chemotherapy and total‑body irradiation before donor stem cell transplant for adults with high‑risk myeloid cancers

  This test tries whether adding decitabine to FLAG‑Ida chemotherapy and total‑body irradiation before a donor stem cell transplant helps adults with high‑risk or relapsed myeloid blood cancers live longer and stay in remission.

  Recruiting Phase 1/2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT06928662

• Interpersonal Communication and Vaccination Workflow Training in Pharmacies to Improve HPV Vaccination Recommendations

  We’re testing whether training pharmacy staff in effective communication and vaccination workflows helps them recommend and provide HPV vaccines more consistently.

  Recruiting Fred Hutchinson Cancer Center · University Park, Pennsylvania and 1 other locations · NCT06926062

• Screening for financial hardship in Alzheimer's and dementia patients

  This study is trying to understand the financial struggles faced by people with Alzheimer's and their caregivers to see how it affects their well-being and care choices.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT06922188

• Digital tool to help young adults quit vaping with ACT on Vaping app

  A smartphone app using Acceptance and Commitment Therapy is tested to see if it helps 18-30 year-olds quit vaping, compared to a version with enhanced text support.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT06909500

• Combination treatment for chronic lymphocytic leukemia and lymphoma

  This study is testing a new combination treatment with sonrotoclax and either zanubrutinib or rituximab to see if it can help patients with chronic lymphocytic leukemia, small lymphocytic lymphoma, and mantle cell lymphoma.

  Recruiting Phase 2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT06839053

• Multilevel approach to boost follow-up colonoscopy after abnormal FIT

  This trial tests a multilevel program to help people with abnormal FIT results complete a follow-up colonoscopy.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT06822530

• Remdesivir for RSV in immunocompromised adults

  This trial tests whether a short course of intravenous remdesivir can help adults whose immune systems are weakened by cellular or bispecific antibody therapies recover from upper respiratory RSV infection.

  Recruiting at 3 sites Phase 2 Fred Hutchinson Cancer Center · Duarte, California and 2 other locations · NCT06817889

• Meal timing during cancer treatment for Alaska Native and American Indian patients

  This test will see if an 8-hour time-restricted eating schedule during neoadjuvant or adjuvant therapy helps Alaska Native and American Indian adults with rectal or certain breast cancers.

  Recruiting Fred Hutchinson Cancer Center · Anchorage, Alaska · NCT06802172

• Unrestricted cash payments for early-stage cancer patients to help with costs

  This trial tests whether giving a monthly unrestricted cash card to newly diagnosed early-stage cancer patients with financial concerns can help with financial hardship and support their treatment.

  Recruiting at 2 sites Fred Hutchinson Cancer Center · Bellingham, Washington and 2 other locations · NCT06771739

• FH-FOLR1 CAR T-cell therapy for children with relapsed or refractory AML

  This trial will test FH-FOLR1 CAR T cells in children aged six and under whose FOLR1-positive acute myeloid leukemia has returned or not responded to treatment.

  Recruiting Phase 1 Fred Hutchinson Cancer Center · Seattle, Washington · NCT06609928

• High-intensity exercise and high-fiber diet for melanoma patients

  This study is testing whether high-intensity exercise and a high-fiber diet can help improve health for melanoma patients receiving immunotherapy.

  Recruiting Fred Hutchinson Cancer Center · Boston, Massachusetts and 1 other locations · NCT06298734

• Cell therapy combined with enzalutamide for advanced prostate cancer

  This study is testing a new combination of cell therapy and a medication called enzalutamide to see if it helps people with advanced prostate cancer live better and longer.

  Recruiting Phase 1/2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT06236139

• IndigeQuit: a culturally tailored quit-smoking smartphone program for American Indian and Alaska Native adults

  This project tests whether the IndigeQuit smartphone app helps American Indian and Alaska Native adults quit smoking more effectively than the NCI QuitGuide app.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT06145763

• Using vorinostat and a radioactive treatment for low PSMA metastatic prostate cancer

  This study is testing if adding vorinostat to a radioactive treatment can help people with low PSMA metastatic prostate cancer feel better and improve their outcomes.

  Recruiting Phase 2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT06145633

• Personalized T cell therapy targeting KRAS G12V in metastatic solid tumors

  This trial tests whether giving a patient's own modified CD8+ and CD4+ T cells engineered to recognize the KRAS G12V mutation can help people with metastatic solid tumors that carry that mutation.

  Recruiting Phase 1 Fred Hutchinson Cancer Center · Seattle, Washington · NCT06043713

• Using cord blood transplant and chemotherapy to treat high-risk blood cancers

  This study is testing if combining umbilical cord blood transplants with certain chemotherapy treatments can help people with high-risk blood cancers do better and have fewer side effects.

  Recruiting Phase 2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT06013423

• Belumosudil treatment for chronic graft versus host disease

  This study is testing if a new drug called belumosudil can help people with chronic graft versus host disease feel better compared to a placebo.

  Recruiting at 5 sites Phase 2 Fred Hutchinson Cancer Center · Duarte, California and 4 other locations · NCT05996627

• Using immunoglobulin therapy to prevent infections after CAR-T cell treatment

  This study is testing if giving extra antibodies through immunoglobulin therapy can help prevent infections in patients receiving CAR-T cell treatment for blood cancers.

  Recruiting at 7 sites Phase 2 Fred Hutchinson Cancer Center · Duarte, California and 6 other locations · NCT05952804

• Weight loss program for Latina breast cancer survivors

  This study tests a weight loss program designed for Latina breast cancer survivors to see if it helps them lose weight and improve their health through online education and support.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT05930483

• Exercise program to slow prostate cancer progression in Black men

  This study is testing whether a 16-week exercise program can help Black men with early-stage prostate cancer slow down the progression of their disease.

  Recruiting Fred Hutchinson Cancer Center · Boston, Massachusetts and 3 other locations · NCT05918263

• Online nutrition education to ease chemotherapy side effects for breast cancer patients

  A online nutrition program is tested alongside standard care to see if it reduces chemotherapy-related side effects in women with stage I–III breast cancer.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT05874297

• Personalized vaccine treatment for advanced melanoma, breast cancer, and lung cancer

  This study is testing a personalized vaccine combined with a treatment called nivolumab to see if it can help people with advanced melanoma, breast cancer, or lung cancer fight their tumors better.

  Recruiting Phase 1 Fred Hutchinson Cancer Center · Seattle, Washington · NCT05098210

• Using fecal microbiota transplant and fiber to treat gut graft versus host disease

  This study is testing whether a combination of fecal microbiota transplant and fiber can help people with gut graft versus host disease feel better.

  Recruiting Phase 1 Fred Hutchinson Cancer Center · Seattle, Washington · NCT05067595

• Combining acalabrutinib and venetoclax for treating tough cases of chronic lymphocytic leukemia and small lymphocytic lymphoma

  This study is testing if combining two medications, acalabrutinib and venetoclax, can help people with tough cases of chronic lymphocytic leukemia or small lymphocytic lymphoma feel better and improve their treatment results.

  Recruiting Phase 2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT04941716

• Oral fiber supplementation for patients receiving stem cell transplants

  This study is testing if taking extra fiber can help people getting stem cell transplants feel better and improve their gut health during treatment.

  Recruiting Fred Hutchinson Cancer Center · Seattle, Washington · NCT04829136

• Mobile app to help cancer patients with advance care planning

  This study tests whether a mobile app can help cancer patients talk about and plan their future care wishes with their families and doctors better than standard care alone.

  Recruiting Fred Hutchinson Cancer Center · Manhasset, New York and 3 other locations · NCT04515810

• Chemotherapy and Stem Cell Transplant for Relapsed or Refractory Blood Cancers

  This study is testing a combination of two chemotherapy treatments and total body radiation to see if it helps people with relapsed or hard-to-treat blood cancers get ready for a stem cell transplant.

  Recruiting Phase 1 Fred Hutchinson Cancer Center · Seattle, Washington · NCT04375631

• Using a JAK inhibitor before and after haploidentical transplantation for myelofibrosis treatment

  This study is testing if a JAK inhibitor can help people with myelofibrosis have a better outcome after a specific type of stem cell transplant by preventing complications and promoting successful recovery.

  Recruiting Phase 2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT04370301

• Donor stem cell transplant with chemotherapy and radiation for blood cancers

  This study is testing if a donor stem cell transplant combined with different doses of chemotherapy and radiation can help people with blood cancers recover better.

  Recruiting Phase 2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT04195633

• Using total body irradiation and a special antibody to treat nonmalignant diseases

  This study is testing a new treatment using total body radiation and a special antibody to help patients with nonmalignant diseases who are getting a stem cell transplant.

  Recruiting Phase 1/2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT04083183

• Using donor stem cells with specific chemotherapy to treat non-cancerous blood disorders

  This study is testing a new treatment using donor stem cells and specific chemotherapy to see if it can help people with non-cancerous blood disorders feel better and improve their health.

  Recruiting Phase 2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT03980769

• Strategies to reduce graft versus host disease in blood stem cell transplant patients with acute leukemia or MDS

  This study is testing two different treatment plans to see which one better helps prevent graft versus host disease in patients with acute leukemia or myelodysplastic syndrome after they receive a blood stem cell transplant.

  Recruiting at 3 sites Phase 2 Fred Hutchinson Cancer Center · Tampa, Florida and 2 other locations · NCT03970096

• Using a radioactive antibody followed by stem cell transplant to treat high-risk leukemia or myelodysplastic syndrome

  This study is testing a new radioactive treatment combined with a stem cell transplant to see if it can help people with high-risk leukemia or myelodysplastic syndrome feel better and improve their chances of recovery.

  Recruiting Phase 1/2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT03670966

• HA-1 TCR T cell therapy for leukemia that returned or didn't respond after a donor stem cell transplant

  This Phase 1 study will test whether giving specially engineered donor T cells called HA-1 TCR T cells is safe and what dose works for people whose acute leukemia came back or didn't respond after a donor stem cell transplant.

  Recruiting Phase 1 Fred Hutchinson Cancer Center · Seattle, Washington · NCT03326921

• Using radioactive treatment before stem cell transplant for high-risk leukemia patients

  This study is testing a new radioactive treatment given before a stem cell transplant to see if it can help high-risk leukemia patients by targeting cancer cells while protecting healthy ones.

  Recruiting Phase 1/2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT03128034

NIH-funded research (newest 40 of 663)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• How brain glia prune neuron fragments in a worm model

  Researchers study how brain support cells called glia remove pieces of living neurons in a tiny worm to learn about brain aging and diseases like Alzheimer's.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11631075

• Understanding and Targeting Lineage Plasticity in Prostate Cancer with Genomic-Based Neoadjuvant Therapy

  A broad research program at Fred Hutchinson Cancer Center is exploring how aggressive prostate cancers change their cell states in response to therapy and how to block these changes.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11625620

• Personalized cancer drug testing on patient tumor cells

  Aiming to test many FDA-approved cancer drugs on a patient’s own tumor cells to identify effective options when standard therapies fail.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11621814

• MOSAAIC: Using health records to track heart disease in Asian American Communities

  A big, dedicated effort is testing whether electronic health records can more quickly and accurately track heart and blood vessel problems in Asian American populations.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11611759

• Targeting gut microbes to prevent progression to multiple myeloma

  Researchers are testing how specific gut bacteria might trigger immune changes linked to early blood cancer stages and whether targeting these microbes could help prevent progression to multiple myeloma.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11541236

• eDyNAmiC: Understanding extrachromosomal DNA in cancer and how it drives aggressiveness

  A cancer research project at Fred Hutchinson Cancer Center is studying abnormal circular DNA pieces (ecDNA) that help cancers grow and resist treatment, with the aim of finding ways to help patients.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11539606

• Pacific Northwest Prostate Cancer Core Grants for Translational Research

  A collaborative effort across major cancer centers to push new prostate cancer advances from basic science to patient care.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11535287

• Stem cell and transplantation resources for researchers and patients

  A national program provides researchers with access to large numbers of human stem cells, viral vectors, and gene-editing tools to advance blood disease research.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11530324

• HIV Prevention Trials Network: Data and Analytics Support

  This grant supports a national network working to find safe, scalable HIV prevention options for people at risk around the world.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11507071

• Prostate cancer models to guide screening, testing, and treatment choices

  A team at Fred Hutchinson Cancer Center is updating computer models to help doctors and patients understand how new tests, imaging, and treatments could change prostate cancer care.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11496283

• Understanding why HIV hides in immune cells and how to make it disappear faster

  Researchers are studying why the HIV reservoir in certain immune cells is so slow to decay and how early treatment might unlock faster clearance for people living with HIV on therapy.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11493678

• Dual germline-targeting approach to spark diverse anti-CD4-BS antibodies against HIV-1

  A new HIV vaccine strategy aims to trigger the body’s early B cells to produce broadly neutralizing antibodies that could protect against many HIV-1 strains.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11471058

• Impact of VRC01 prophylaxis on HIV viral diversity and autologous antibody responses after infection

  This project studies how giving a broadly neutralizing antibody (VRC01) before HIV infection may shape the virus and the body's own antibodies after infection in people who become HIV-positive anyway.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11470486

• Improving how HIV antibodies behave in the body across species

  A short, patient-friendly description of a project to better predict how HIV-fighting antibodies move and stay in the body, using information from multiple animal models.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11469120

• Bioinformatics platform to map HIV vaccine B-cell responses

  A national HIV vaccine research center is building a beginner-friendly data platform to study how B cells respond to HIV vaccines in people, with the goal of improving vaccines.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11468160

• How T cells spot protein fragments from viruses, tumors, and self

  This project will build much larger maps linking T cell receptors to the protein fragments they recognize to help people with infections, cancer, or autoimmune diseases.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11457395

• Using big biobanks to understand shared cancer risks

  This grant uses large genetic databases to find common genetic factors that influence multiple cancer types, helping us understand why some people are at risk for more than one cancer.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11456223

• Optimizing the dose of post-transplant cyclophosphamide for stem cell transplant patients

  Researchers are testing the best dose of a drug given after stem cell transplants to reduce complications and improve recovery for people who need donor stem cells.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11451114

• Mucosal regulatory T cells help shape memory T cell responses

  A project exploring how tissue-regulating T cells influence memory T cells to protect against infections while keeping tissues safe.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11446847

• Acupuncture to ease symptoms for people with metastatic breast cancer

  A clinical trial will test whether weekly acupuncture for 12 weeks can reduce symptom burden for people with metastatic breast cancer who are on standard therapy.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11441799

• Understanding how immune cells protect against malaria vaccines in children

  A doctor-researcher is studying how immune cells respond to three malaria vaccines in healthy volunteers, to learn what kinds of cellular signals best predict protection.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11437755

• RSV Fusion Protein: mapping how mutations change antibody binding

  A researcher will map which mutations in the RSV fusion protein allow the virus to escape antibodies, using safe, non-infectious systems to help improve future vaccines and antibody therapies for people of all ages.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11435691

• Dissecting how MCPyV ALTO controls tumor suppression

  Aims to understand how the MCPyV ALTO protein helps stop Merkel cell carcinoma from growing and how this could improve immune system–driven treatments.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11435127

• Understanding why bladder cancer spreads and resists treatment

  This grant studies how advanced bladder cancer changes and spreads across the body, aiming to uncover why it’s hard to treat.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11435060

• URBANE2: Following AI/AN elders to understand Alzheimer’s and related dementias over time

  A long-term study in AI/AN adults 55+ in five cities will track brain health and cognitive changes to identify risk and protective factors for dementia.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11435010

• Personalized guidance for menopausal hormone therapy

  A new program aims to give individualized risk guidance for menopausal hormone therapy to help women make safer, informed decisions.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11425194

• Long-Term Follow-Up for Patients After Transplant and Cellular Immunotherapy

  A long-term data collection effort following people who had hematopoietic cell transplants or cellular immunotherapy to track health after treatment.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11420388

• High-dimensional cellular and spatial analysis for AML research

  A core team at a major cancer center is helping multiple AML projects analyze very complex single-cell and spatial data to uncover new biology and hypotheses.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11420383

• Biostatistics, data management, and computing support for cancer research

  This grant funds a core that provides biostatistics, computing, data collection, and data management services to support cancer research projects.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11420380

• Transgenic T Cell Therapy for AML in Adults

  A patient-centered approach uses engineered autologous T cells to target AML in adults who may not be eligible for transplant.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11420378

• Engineering Better T Cell Therapy for Multiple Myeloma

  A patient-focused program to improve CAR-T cell therapy for multiple myeloma by making T cells more sensitive and able to target multiple cancer markers.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11420374

• Understanding how immune escape happens after CAR-T and transplant therapies

  This grant explores why cancer cells slip past immune therapies after transplant or CAR-T treatment, with the goal of making future treatments safer and more effective for patients.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11420373

• Administrative Core for a Program Project in Hematologic Cancers

  A central, money-and-meeting hub supports a team researching blood cancers by coordinating researchers, tracking progress, and ensuring NIH rules are followed.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11420372

• Adult Leukemia Research Center: Understanding and Preventing Immune Toxicity in Adoptive Cell Therapies

  Researchers at Fred Hutchinson Cancer Center are studying how the immune system reacts to advanced cell therapies for AML and multiple myeloma to prevent dangerous side effects and improve treatment success for adults over 60.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11420371

• Telehealth-supported PrEP/PEP delivery through private pharmacies

  A study is testing a telehealth model where private pharmacies help people access HIV PrEP and PEP with remote nurse support to reduce barriers and stigma.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11417150

• Understanding how genes and environment work together to affect colorectal cancer risk

  This project explores how genetic factors and lifestyle or environmental factors combine to influence colorectal cancer risk, with the goal of guiding personalized prevention in patients.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11416477

• Biostatistical support to advance prostate cancer research and cancer detection models

  A biostatistics-focused NIH grant supports a team in using data, modeling, and software to improve prostate cancer research and test new cancer-detection approaches.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11415752

• Career Development for Translational Prostate Cancer Research

  A support program helps new and current researchers grow careers in translational prostate cancer, bridging basic, clinical, and population science.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11415679

• Developmental Research Program for Prostate Cancer Translational Work

  A funded program to explore early translational ideas in prostate cancer that could change how the disease is prevented or treated.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11415673

• Biostatistics and Bioinformatics Core for Pacific Northwest Prostate Cancer SPORE

  A dedicated Biostatistics and Bioinformatics Core will support researchers working on prostate cancer by guiding study design, data handling, and advanced analyses.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11415668

Quick answers

How many clinical trials run by Fred Hutchinson Cancer Center are recruiting right now?

64, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (59 trials), Zimbabwe (2 trials), Kenya (1 trial), Rwanda (1 trial), South Africa (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 17, Phase 1/2: 8, Phase 1: 8. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →