Tailored Patient Navigation to Boost Lung Cancer Screening in Tribal Communities

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants are randomized to receive either tailored patient navigation for 21 months plus an LCS educational handout, or enhanced usual care with a hand-off to discuss LCS followed by 15 months of navigation for those in the second arm. The study uses patient navigation, education, interviews, and surveys to support uptake and follow-up of low-dose CT screening for those aged 50–77 with a 20-pack-year smoking history and recent tobacco use. Settings are two tribal-affiliated clinics in Washington state, with activity spanning clinical staff and patient perspectives. The trial aims to understand how navigation strategies affect screening uptake among AI/AN communities and gather stakeholder insights.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* AIM 1.2 RANDOMIZED CONTROLLED TRIAL: Between ages 50-77
* AIM 1.2 RANDOMIZED CONTROLLED TRIAL: Self-reported 20-pack year smoking history
* AIM 1.2 RANDOMIZED CONTROLLED TRIAL: Ongoing commercial tobacco use within the past 15 years
* AIM 1.2 RANDOMIZED CONTROLLED TRIAL: Seen by a PCP at a participating clinic (South Puget Intertribal Planning Agency \[SPIPA\] or Muckleshoot) within the past three years

  * Potential participants who want to establish care at an eligible clinic will be connected to a PCP
* AIM 2 CLINICAL STAFF SURVEYS AND SEMI-STRUCTURED INTERVIEWS: At least 18 years of age
* AIM 2 CLINICAL STAFF SURVEYS AND SEMI-STRUCTURED INTERVIEWS: Affiliation with Muckleshoot or SPIPA (one of the 6 community partnering clinics) as a provider, or supportive staff member
* AIM 2 PATIENT SURVEYS AND SEMI-STRUCTURED INTERVIEWS: Patient participated in the aim 1.2 trial
* AIM 3 CLINICAL STAFF SURVEYS AND SEMI-STRUCTURED INTERVIEWS: At least 18 years of age
* AIM 3 CLINICAL STAFF SURVEYS AND SEMI-STRUCTURED INTERVIEWS: Affiliation with Muckleshoot or SPIPA (one of the 6 community partnering clinics) as a provider, or supportive staff member
* AIM 3 PATIENT SURVEYS AND SEMI-STRUCTURED INTERVIEWS: Patient participated in the aim 1.2 trial

Exclusion Criteria:

* AIM 1.2 RANDOMIZED CONTROLLED TRIAL: Has had a documented chest CT within the past one year
* AIM 1.2 RANDOMIZED CONTROLLED TRIAL: Personal history of lung cancer
* AIM 1.2 RANDOMIZED CONTROLLED TRIAL: Personal history of any cancer within 5 years except for basal cell or squamous cell skin carcinoma

Where it's running

• Muckleshoot Tribal Clinic
  Auburn, Washington, United States Recruiting
• South Puget Intertribal Planning Agency (SPIPA)
  Shelton, Washington, United States Recruiting

Study contacts

• Principal investigator: Matty Triplette, MD, MPH — Fred Hutch/University of Washington Cancer Consortium
• Study coordinator: Matty Triplette, MD, MPH
• Email: mtriplet@fredhutch.org
• Phone: (206) 667-6335

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.