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Clinical trials and research at Baylor Research Institute

• 25Clinical trials
• 9NIH research projects
• 1Country

Newest trials

All recruiting trials (25)

• Radiation-Exposure Reduction in Peripheral Procedures using Rampart IC System

  This study tests whether using the Rampart IC System during elective femoral-artery access peripheral procedures reduces radiation exposure for patients.

  Recruiting Baylor Research Institute · Plano, Texas · NCT07467720

• Microbiome in esophageal and stomach leaks

  This project will test whether microbes in leaked fluid and nearby tissue from adults with esophageal or stomach leaks differ in ways that affect healing and complications.

  Recruiting Baylor Research Institute · Dallas, Texas · NCT07424469

• IVUS-guided revascularization of leg arteries

  This trial will test whether using ultrasound inside the blood vessels during minimally invasive treatment of leg arteries improves outcomes for adults with symptomatic peripheral artery disease.

  Recruiting at 4 sites Baylor Research Institute · Dallas, Texas and 5 other locations · NCT07353905

• Robotic exoskeletons for early walking after heart or chest surgery

  This will try using a wearable robotic exoskeleton to help adults who had heart or chest surgery get up and walk sooner compared with usual early ambulation.

  Recruiting Baylor Research Institute · Dallas, Texas · NCT07353892

• Donor human milk cream to treat low blood sugar in newborns

  This pilot will see if a pasteurized donor human milk cream given to newborns at risk for low blood sugar can raise and help sustain their blood glucose.

  Recruiting Baylor Research Institute · McKinney, Texas · NCT07217483

• CardioMEMS-assisted LVAD management in heart failure

  This pilot study tests whether using CardioMEMS to monitor pulmonary pressures in LVAD patients reduces heart failure hospitalizations compared with standard care.

  Recruiting Baylor Research Institute · Plano, Texas · NCT07096544

• Comparing coronary flow and microvascular measures before and after intracoronary nitroglycerin in people with angina and non-blocking coronary arteries

  This study will try whether giving a small dose of nitroglycerin inside the coronary artery changes blood-flow and microvascular measurements in adults with angina but no major blockages.

  Recruiting Baylor Research Institute · Plano, Texas · NCT06896903

• Telehealth program for lifestyle changes in stroke survivors

  This study tests whether a telehealth program can help stroke survivors make healthy lifestyle changes with support from others over six months.

  Recruiting Baylor Research Institute · Dallas, Texas · NCT06569121

• Culturally adapted healthy lifestyle program for Hispanic/Latino stroke survivors

  This project will try a culturally adapted 12-month Group Lifestyle Balance program to help Hispanic/Latino adults who have had a stroke lose weight and improve diet and physical activity.

  Recruiting Baylor Research Institute · Dallas, Texas · NCT06517459

• Weight loss treatment for early breast cancer using tirzepatide

  This study is testing if the weight loss drug tirzepatide can help overweight or obese women with early breast cancer live longer and healthier by reducing harmful tumor markers in their blood.

  Recruiting Phase 2 Baylor Research Institute · Dallas, Texas · NCT06517212

• Robotic gait training for stroke recovery

  This study is testing whether robotic gait training can help people recovering from a stroke walk better compared to regular gait training.

  Recruiting Baylor Research Institute · Dallas, Texas · NCT06430632

• Long-term outcomes of the Ross procedure for aortic valve replacement

  This study looks at how well the Ross procedure, which uses a person's own valve to replace a damaged aortic valve, works over the long term for patients needing heart surgery.

  Recruiting Baylor Research Institute · Plano, Texas · NCT06352671

• Intracardiac versus transesophageal guidance for left atrial appendage closure

  This trial will test whether using intracardiac echocardiography (ICE) instead of transesophageal echocardiography (TEE) to guide left atrial appendage closure is safe and works well for people with non-valvular atrial fibrillation who want a non-drug option to reduce stroke risk.

  Recruiting Baylor Research Institute · Plano, Texas · NCT06348394

• Prolonged Exposure Therapy for PTSD in Trauma Patients

  This study is testing a short therapy called Brief Prolonged Exposure Therapy to see if it can help trauma patients avoid PTSD and improve their mental health after serious injuries.

  Recruiting at 3 sites Baylor Research Institute · Dallas, Texas and 2 other locations · NCT06210711

• Combining neratinib and ruxolitinib for treating metastatic triple-negative breast cancer

  This study is testing if combining two medications, neratinib and ruxolitinib, can help people with advanced triple-negative breast cancer who have already been treated with chemotherapy.

  Recruiting Early Phase 1 Baylor Research Institute · Dallas, Texas · NCT06008275

• Collection of biospecimens from cancer patients for biomarker analysis

  This study is collecting samples from cancer patients to see how their biology affects treatment outcomes and to improve our understanding of cancer.

  Recruiting at 8 sites Baylor Research Institute · College Station, Texas and 7 other locations · NCT05371756

• Chemotherapy combined with anakinra for pancreatic adenocarcinoma

  This will try adding anakinra to pre- and post-operative chemotherapy in adults with resectable or locally advanced pancreatic adenocarcinoma to see if outcomes improve.

  Recruiting Phase 2 Baylor Research Institute · Dallas, Texas · NCT04926467

• Surgery to reduce GERD in patients revising from sleeve gastrectomy to gastric bypass

  This study is testing whether a specific type of surgery can help adults who had sleeve gastrectomy and now suffer from GERD feel better after switching to gastric bypass.

  Recruiting Baylor Research Institute · Dallas, Texas · NCT04901429

• How cardiopulmonary exercise affects AlloSure donor-derived cell-free DNA in heart transplant recipients

  This will test whether exercise changes donor-derived cell-free DNA measured by AlloSure in people who have had heart transplants.

  Recruiting Baylor Research Institute · Dallas, Texas · NCT04656080

• Using hearts from donors with active hepatitis C (HCV NAT+) for transplantation

  This tests whether receiving a heart from a donor with active hepatitis C (HCV NAT+) is safe and leads to acceptable outcomes for people having a heart transplant.

  Recruiting Baylor Research Institute · Dallas, Texas · NCT04493385

• Bortezomib followed by pembrolizumab and cisplatin for metastatic triple-negative breast cancer

  This study is testing if a combination of bortezomib, pembrolizumab, and cisplatin can help people with metastatic triple-negative breast cancer by looking at how their tumors respond to the treatment.

  Recruiting Early Phase 1 Baylor Research Institute · Dallas, Texas · NCT04265872

• Alirocumab for people on stable dialysis

  This study tests whether alirocumab can safely lower cholesterol in adults on stable hemodialysis or peritoneal dialysis over 12 weeks.

  Recruiting Phase 3 Baylor Research Institute · Dallas, Texas · NCT03480568

• Using hepatitis C–positive donor hearts for hepatitis C–negative recipients treated with Epclusa

  This test will see if giving Epclusa to hepatitis C–negative heart transplant recipients prevents hepatitis C infection and allows safe use of hearts from HCV-positive donors.

  Recruiting at 2 sites Phase 2 Baylor Research Institute · Los Angeles, California and 2 other locations · NCT03383419

• Graft function after autologous islet transplantation

  We will see if measuring inflammatory markers in blood before and after total pancreatectomy with islet autotransplantation helps explain how well transplanted islet cells work in adults with chronic pancreatitis.

  Recruiting Baylor Research Institute · Dallas, Texas · NCT03097185

• Registry for evaluating treatments in patients with Peripheral Arterial Disease

  This study is trying to see how well different treatments work for people with Peripheral Arterial Disease by looking at data from 14,000 patients who have had procedures to improve blood flow.

  Recruiting at 7 sites Baylor Research Institute · Little Rock, Arkansas and 23 other locations · NCT01904851

NIH-funded research (9)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Peer-delivered emotion-regulation training to prevent mental health problems in firefighter trainees

  A peer-led program teaches new firefighters emotion-regulation skills to help prevent PTSD, depression, anxiety, and problematic alcohol use during the early years on the job.

  NIH research Baylor Research Institute · Dallas, United States · NIH-11394109

• Credible vaccine protection measures for Flu, COVID-19, and other respiratory viruses in Texas ambulatory care

  This project looks at how well flu and COVID-19 vaccines protect people from visiting clinics for acute respiratory illnesses in Central Texas.

  NIH research Baylor Research Institute · Dallas, United States · NIH-11380358

• Rapid, multi-drug initiation for people with CKD and type 2 diabetes

  A small study will try starting several key diabetes and kidney medicines at the same time in adults with CKD and type 2 diabetes to see if this fast plan is safe and helpful.

  NIH research Baylor Research Institute · Dallas, United States · NIH-11343746

• How gain-of-function gene changes affect human diseases

  Researchers are using computer network models to figure out how certain gene changes called gain-of-function mutations can disrupt cellular processes and contribute to disease, aiming to help people with genetic conditions.

  NIH research Baylor Research Institute · Dallas, United States · NIH-11260564

• How flu, COVID-19, and other respiratory virus vaccines protect against outpatient respiratory illness in Central Texas

  This project measures how well flu, COVID-19, and other respiratory virus vaccines prevent people in Central Texas from getting sick enough to seek outpatient medical care.

  NIH research Baylor Research Institute · Dallas, United States · NIH-11170367

• Peer-led emotion regulation training for new firefighters

  This project offers peer-delivered training to help new firefighter trainees build emotion-regulation skills to reduce risk for PTSD, alcohol problems, depression, and related harms.

  NIH research Baylor Research Institute · Dallas, United States · NIH-11125734

• Identifying cancer risk in patients with Barrett's esophagus using a new test

  This study is looking at how to better spot patients with Barrett's esophagus who might be at risk for developing esophageal cancer, using a special test on biopsy samples to find early signs of trouble, so we can help manage their health more effectively.

  NIH research Baylor Research Institute · Dallas, United States · NIH-11114067

• Evaluating the effectiveness of vaccines for flu and COVID-19 against acute illnesses in Texas.

  This study is looking at how well the flu and COVID-19 vaccines help keep people in Central Texas from getting sick enough to need a doctor's visit, so we can better understand their effectiveness over time.

  NIH research Baylor Research Institute · Dallas, United States · NIH-10910859

• Evaluating driving safety in older adults recovering from critical illness

  This study is looking at how serious illnesses can affect older adults' driving skills, and it aims to create helpful tools to keep them safe on the road while also improving their overall well-being after their hospital stay.

  NIH research Baylor Research Institute · Dallas, United States · NIH-10813218

Quick answers

How many clinical trials run by Baylor Research Institute are recruiting right now?

25, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Early Phase 1: 2, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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