Microbiome in esophageal and stomach leaks

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Investigators will collect infected fluid and tissue biopsy samples from adults who have an esophageal or stomach leak and compare the microbial composition and virulence within and between participants. They will analyze changes in the microbiota that occur with the leak and characterize host response mechanisms from the tissue samples. Comparisons of fluid versus tissue microbiomes will help define which microbial features are associated with worse outcomes or higher risk of postoperative leaks. The results aim to inform preventative approaches and improve patient management after foregut leaks.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with an esophageal or stomach leak
* Over 18 years old

Exclusion Criteria:

* Patients determined by physician/surgeon as not able to tolerate biopsy
* Under 18 years old

Where it's running

• Baylor Scott & White Center for Advanced Surgery
  Dallas, Texas, United States Recruiting

Study contacts

• Study coordinator: Rehma Shabbir
• Email: Rehma.Shabbir@BSWHealth.org
• Phone: 2148201722

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.