Credible vaccine protection measures for Flu, COVID-19, and other respiratory viruses in Texas ambulatory care
Official title: RFA-IP-22-004, Component A _ Credible Effectiveness Measures of Seasonal Influenza, COVID-19 and Other Respiratory Virus Vaccines against Ambulatory Care for Acute Illness in Texas (and Component D).
Funded at Baylor Research Institute · NIH-11380358 · Data updated 2026-11-12
This project looks at how well flu and COVID-19 vaccines protect people from visiting clinics for acute respiratory illnesses in Central Texas.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor Research Institute NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project start | September 30, 2022 |
| Project end | September 29, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,316,666 |
| NIH project number | 5U01IP001189-05 |
| Project ID | NIH-11380358 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults and children enrolled in the Baylor Scott & White Health system in Central Texas who have documented vaccination status and seek care for acute respiratory illness.
✕Less likely to help
Individuals without acute respiratory illness or without access to vaccination records in the study network may not directly benefit.
What this research studies
Researchers at Baylor Research Institute will use real-world data from Baylor Scott & White Health to estimate how well influenza and COVID-19 vaccines protect people against outpatient visits for acute respiratory illnesses. The study will track lab-confirmed cases of flu, COVID-19, and other respiratory viruses and compare vaccination status to observed protection over time. The goal is to provide timely, reliable vaccine effectiveness estimates to inform vaccination programs and public health decisions for the Texas population. Results will help guide future vaccine strategies and monitoring of protection duration after vaccination.
Why it matters
Potential benefit: If successful, the findings could improve understanding of how well current vaccines protect people in real-world settings and inform vaccination recommendations to reduce outpatient illness.
How similar studies have gone: Previous real-world VE studies have shown valuable, actionable estimates, and this study aims to provide ongoing, location-specific estimates for Texas.
Where this research is happening
-
Baylor Research Institute
Dallas, United States Active
Researchers
- Principal investigator: Gaglani, Manjusha — Baylor Research Institute
- Study coordinator: Gaglani, Manjusha
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How well flu, COVID-19, and other respiratory vaccines protect people in southeastern Michigan
This project checks how well seasonal flu, COVID-19, and other respiratory vaccines protect people who visit clinics for coughs, colds, or breathing problems in southeastern Michigan.
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How flu, COVID-19, and other respiratory virus vaccines protect against outpatient respiratory illness in Central Texas
This project measures how well flu, COVID-19, and other respiratory virus vaccines prevent people in Central Texas from getting sick enough to seek outpatient medical care.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.