Long-term outcomes of the Ross procedure for aortic valve replacement
Prospective Long-Term Outcomes of a Standardized Ross Procedure
Baylor Research Institute · NCT06352671
This study looks at how well the Ross procedure, which uses a person's own valve to replace a damaged aortic valve, works over the long term for patients needing heart surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 225 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Baylor Research Institute (other) |
| Locations | 1 site (Plano, Texas) |
| Trial ID | NCT06352671 on ClinicalTrials.gov |
What this trial studies
This observational study analyzes the long-term outcomes of the Ross procedure, which replaces a diseased aortic valve with a patient's own pulmonary valve. It aims to gather data from multiple centers to identify best practices for stabilizing the autograft and reconstructing the right ventricular outflow tract. The study addresses the uncertainties surrounding aortic valve replacement options and seeks to reaffirm the benefits of the Ross procedure compared to traditional methods. By focusing on a multicenter cohort, it aims to provide robust evidence on the safety and efficacy of this surgical approach.
Who should consider this trial
Good fit: Ideal candidates for this study are adults undergoing the Ross procedure at participating medical centers.
Not a fit: Patients under 18 years of age, those with active malignancies, pregnant individuals, or those unable to provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide evidence supporting the Ross procedure as a superior option for long-term aortic valve replacement, potentially improving patient outcomes.
How similar studies have performed: Recent publications from expert centers have shown promising outcomes for the Ross procedure, suggesting that this approach is gaining recognition and support in the medical community.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing Ross procedure at Baylor Scott and White The Heart Hospital, Plano, The University of Pennsylvania, The University of Washington, and Northwestern University. Exclusion Criteria: * Less than 18 years of age * Presence of active malignancy * Pregnant at the time of surgery * Inability to provide informed consent
Where this trial is running
Plano, Texas
- Baylor Scott and White Heart Hospital — Plano, Texas, United States (RECRUITING)
Study contacts
- Study coordinator: Bonnie Ostergren
- Email: Bonnie.Ostergren@BSWHealth.org
- Phone: 4698144181
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Aortic Valve Disease