Prolonged Exposure Therapy for PTSD in Trauma Patients
Prevention of Posttraumatic Stress: A Randomized Controlled Trial of Brief Prolonged Exposure Therapy for Injured Individuals Admitted to a Level I Trauma Center
This study is testing a short therapy called Brief Prolonged Exposure Therapy to see if it can help trauma patients avoid PTSD and improve their mental health after serious injuries.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Baylor Research Institute Academic / other |
| Locations | 3 sites (Dallas, Texas and 2 other locations) |
| Trial ID | NCT06210711 on ClinicalTrials.gov |
What this trial studies
This research aims to evaluate the effectiveness of a brief treatment method, specifically Brief Prolonged Exposure Therapy (Brief PE), for preventing posttraumatic stress disorder (PTSD) and other psychological issues following traumatic injuries. The study involves a prospective randomized controlled trial where participants admitted to Level I Trauma Centers will receive either Brief PE or standard clinical care. The intervention consists of three 60-minute sessions aimed at reducing psychological distress and improving long-term health outcomes, including depression and quality of life, assessed at 1, 3, and 6 months post-injury.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 75 who have been admitted to a Level I Trauma Center following a traumatic injury.
Not a fit: Patients who are in police custody, not fluent in English, have severe cognitive impairment, are acutely suicidal, or have active psychosis may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly reduce the incidence of PTSD and improve overall mental health outcomes for trauma patients.
How similar studies have performed: Other studies have shown promising results with similar therapeutic approaches, indicating potential for success in this novel application.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Between the ages of 18 and 75 years old. * Admitted to Baylor University Medical Center at Dallas (BUMC), Baylor Scott \& White Medical Center at Temple (BSWMC), or Froedtert Hospital and the Medical College of Wisconsin (FH/MCW) Level 1 Trauma Center Exclusion Criteria: * Patients in police custody * Patients not fluent in English * Patients with severe cognitive impairment * Patients who are acutely suicidal * Patients with active psychosis
Where this trial is running
Dallas, Texas and 2 other locations
- Baylor University Medical Center — Dallas, Texas, United States (Recruiting)
- Baylor Scott & White Medical Center - Temple — Temple, Texas, United States (Recruiting)
- Froedtert & Medical College of Wisconsin — Milwaukee, Wisconsin, United States (Recruiting)
Study contacts
- Principal investigator: Ann Marie Warren, PhD — Baylor Scott & White Research Institute
- Study coordinator: Alexis Evans, M.S
- Email: Alexis.Evans@BSWHealth.org
- Phone: (214) 820-9918
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.