Surgery to reduce GERD in patients revising from sleeve gastrectomy to gastric bypass

Truncal Vagotomy in Patients Undergoing Revisional Sleeve Gastrectomy to Gastric Bypass

Not applicable Interventional Baylor Research Institute · NCT04901429

This study is testing whether a specific type of surgery can help adults who had sleeve gastrectomy and now suffer from GERD feel better after switching to gastric bypass.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment200 (estimated)
Ages18 Years and up
SexAll
SponsorBaylor Research Institute Academic / other
Locations1 site (Dallas, Texas)
Trial IDNCT04901429 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of performing a truncal vagotomy in conjunction with revisional sleeve gastrectomy to gastric bypass surgery. The primary focus is on reducing the severity and incidence of gastroesophageal reflux disease (GERD) in patients who have previously undergone sleeve gastrectomy. Participants must be over 18 years old and eligible for the revision surgery. The study aims to provide insights into the potential benefits of this surgical approach for managing GERD post-operatively.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old who are eligible for sleeve to bypass revision bariatric surgery.

Not a fit: Patients under 18 years old or those not eligible for sleeve to bypass revision bariatric surgery may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce GERD symptoms in patients undergoing revisional bariatric surgery.

How similar studies have performed: While the specific combination of truncal vagotomy with revisional bariatric surgery is novel, similar surgical interventions have shown promise in managing GERD.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participating subjects will need to be \>18yrs of age and eligible for sleeve to bypass revision bariatric surgery.
* Undergoing sleeve to bypass revision bariatric surgery.

Exclusion Criteria:

* Patients who are under the age of 18.
* Not eligible for sleeve to bypass revision bariatric surgery.

Where this trial is running

Dallas, Texas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions GERD
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.