Surgery to reduce GERD in patients revising from sleeve gastrectomy to gastric bypass
Official title: Truncal Vagotomy in Patients Undergoing Revisional Sleeve Gastrectomy to Gastric Bypass
Run by Baylor Research Institute · NCT04901429 · Data updated 2026-11-12
This study is testing whether a specific type of surgery can help adults who had sleeve gastrectomy and now suffer from GERD feel better after switching to gastric bypass.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Baylor Research Institute Academic / other |
| Locations | 1 site (Dallas, Texas) |
| Status | Recruiting |
| Started | July 1, 2021 |
| Main results expected | August 1, 2027 |
| Study ends | August 1, 2028 |
| Registry record updated | May 25, 2025 |
| Trial ID | NCT04901429 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old who are eligible for sleeve to bypass revision bariatric surgery.
✕Probably not a fit
Patients under 18 years old or those not eligible for sleeve to bypass revision bariatric surgery may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effectiveness of performing a truncal vagotomy in conjunction with revisional sleeve gastrectomy to gastric bypass surgery. The primary focus is on reducing the severity and incidence of gastroesophageal reflux disease (GERD) in patients who have previously undergone sleeve gastrectomy. Participants must be over 18 years old and eligible for the revision surgery. The study aims to provide insights into the potential benefits of this surgical approach for managing GERD post-operatively.
Why it matters
Potential benefit: If successful, this approach could significantly reduce GERD symptoms in patients undergoing revisional bariatric surgery.
How similar studies have gone: While the specific combination of truncal vagotomy with revisional bariatric surgery is novel, similar surgical interventions have shown promise in managing GERD.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participating subjects will need to be \>18yrs of age and eligible for sleeve to bypass revision bariatric surgery. * Undergoing sleeve to bypass revision bariatric surgery. Exclusion Criteria: * Patients who are under the age of 18. * Not eligible for sleeve to bypass revision bariatric surgery.
Where it's running
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Baylor University Medical Center
Dallas, Texas, United States Recruiting
Study contacts
- Study coordinator: Research Project Coordinator
- Email: ADVANCEDSURGERYRESEARCH@bswhealth.org
- Phone: 214-820-4787
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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This project will collect esophageal function tests (manometry, pH-impedance, FLIP) and clinical data from adults with reflux or swallowing symptoms to see if combining these results helps guide diagnosis and long-term care.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.