Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Surgery to reduce GERD in patients revising from sleeve gastrectomy to gastric bypass

Official title: Truncal Vagotomy in Patients Undergoing Revisional Sleeve Gastrectomy to Gastric Bypass

Run by Baylor Research Institute · NCT04901429 · Data updated 2026-11-12

This study is testing whether a specific type of surgery can help adults who had sleeve gastrectomy and now suffer from GERD feel better after switching to gastric bypass.

More GERD trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment200 (estimated)
SponsorBaylor Research Institute
Academic / other
Locations1 site (Dallas, Texas)
StatusRecruiting
StartedJuly 1, 2021
Main results expectedAugust 1, 2027
Study endsAugust 1, 2028
Registry record updatedMay 25, 2025
Trial IDNCT04901429 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 18 years old who are eligible for sleeve to bypass revision bariatric surgery.

Probably not a fit

Patients under 18 years old or those not eligible for sleeve to bypass revision bariatric surgery may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of performing a truncal vagotomy in conjunction with revisional sleeve gastrectomy to gastric bypass surgery. The primary focus is on reducing the severity and incidence of gastroesophageal reflux disease (GERD) in patients who have previously undergone sleeve gastrectomy. Participants must be over 18 years old and eligible for the revision surgery. The study aims to provide insights into the potential benefits of this surgical approach for managing GERD post-operatively.

Why it matters

Potential benefit: If successful, this approach could significantly reduce GERD symptoms in patients undergoing revisional bariatric surgery.

How similar studies have gone: While the specific combination of truncal vagotomy with revisional bariatric surgery is novel, similar surgical interventions have shown promise in managing GERD.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participating subjects will need to be \>18yrs of age and eligible for sleeve to bypass revision bariatric surgery.
* Undergoing sleeve to bypass revision bariatric surgery.

Exclusion Criteria:

* Patients who are under the age of 18.
* Not eligible for sleeve to bypass revision bariatric surgery.

Where it's running

  • Baylor University Medical Center
    Dallas, Texas, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.