Collection of biospecimens from cancer patients for biomarker analysis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Texas Immuno-Oncology Biorepository (TIOB) aims to collect and store a variety of biospecimens, including tissue, blood, urine, and stool, from cancer patients undergoing standard surgical interventions or FDA-approved immunotherapies. This observational study will gather comprehensive clinical and radiological data from a diverse patient population, allowing for in-depth analysis of immunological and molecular biomarkers. The biorepository will facilitate various studies, including genomic, proteomic, and immune cell analysis, to enhance understanding of cancer biology and treatment outcomes. By integrating multi-omics technologies, the TIOB seeks to uncover complex biological interactions that influence cancer progression and treatment resistance.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Participant is over 18 years of age at the time of signing the informed consent form.
* Participant is able and willing to sign an informed consent form.
* Participant is suspected by a provider of being at risk for developing cancer,

OR

* Participant has confirmed or clinically suspected malignancy by a provider. This includes but is not limited to:

  1. Participants who may be candidates for or are scheduled to receive standard of care immunotherapy treatment for the first time for their current cancer diagnosis, regardless of any prior non-immunotherapy treatment.
  2. Participants who are enrolled in a clinical trial to receive an investigational, novel immunotherapy drug for the first time for their current cancer diagnosis.
  3. Participants who may be surgical candidates for their current cancer diagnosis, regardless of any prior treatment.

Exclusion Criteria:

* Participant is unable or unwilling to donate blood.
* Concurrent medical or psychiatric condition or disease that may compromise the ability to give documented informed consent, is likely to interfere with study procedures or results, or that in the opinion of the investigator would constitute a hazard for participating in this study.

Where it's running

• Baylor Scott & White Medical Center - College Station
  College Station, Texas, United States Recruiting
• Baylor University Medical Center - Dallas
  Dallas, Texas, United States Recruiting
• Baylor Scott & White All Saints Medical Center - Fort Worth
  Fort Worth, Texas, United States Recruiting
• Baylor Scott & White Medical Center - Plano
  Plano, Texas, United States Recruiting
• Baylor Scott & White Medical Center - Round Rock
  Round Rock, Texas, United States Recruiting
• Baylor Scott & White Medical Center - Temple
  Temple, Texas, United States Recruiting

Study contacts

• Principal investigator: Ronan J Kelly, MD, MBA — Baylor Scott & White Research Institute
• Study coordinator: Pukar Ratti, MSChE, MSHCM
• Email: TIOBReferral@BSWHealth.org
• Phone: 214-818-8472

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.