Condition

Weight Management clinical trials and research

• 11Clinical trials
• 39NIH research projects
• 21Countries

Newest Weight Management clinical trials

All recruiting trials (11)

• Family-based weight wellness with medically tailored groceries and group visits

  We’re testing a family-focused program that uses group medical visits and medically tailored groceries to help kids 12–17 with overweight or obesity, along with their parents.

  Recruiting at 2 sites Tufts University · Boston, Massachusetts and 1 other locations · NCT07717658

• Elecoglipron for weight management in adults with obesity or overweight with or without type 2 diabetes

  This study tests whether taking elecoglipron once daily helps adults with obesity or overweight, with or without type 2 diabetes, lose more weight than placebo when combined with diet and exercise.

  Recruiting at 220 sites Phase 3 AstraZeneca · Birmingham, Alabama and 324 other locations · NCT07667803

• Weight management program for breast cancer survivors in rural communities

  This program will test whether a 12-week remote WeCan-Rural program helps rural breast cancer survivors with obesity lose weight, ease symptoms, and lower heart disease risk.

  Recruiting at 5 sites Duke University · Durham, North Carolina and 4 other locations · NCT07426952

• Hope‑D digital weight management program for pregnancy and the first six months after birth

  This test tries the Hope‑D digital weight management program with pregnant women who had a pre-pregnancy BMI of 30 or higher to support weight during pregnancy and through six months postpartum.

  Recruiting Turku University Hospital · Turku, Finland · NCT07272824

• Oral ecnoglutide tablets for weight management in Chinese adults with overweight or obesity

  This trial will test whether daily or weekly oral ecnoglutide tablets help Chinese adults with overweight or obesity and are safe and well tolerated.

  Recruiting Phase 1/2 Hangzhou Sciwind Biosciences Co., Ltd. · Beijing, Beijing Municipality · NCT07243171

• Improving team-based biopsychosocial training so clinics can deliver recommended obesity care

  This project will test two training methods to help clinic teams (primary care clinicians, behavioral health staff, dietitians, and community health workers) deliver USPSTF-recommended obesity care to patients at Federally Qualified Health Centers.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT07049861

• Reducing heart disease risk in 12–15-year-olds with severe obesity

  This will try semaglutide in 12–15-year-olds with class 2–3 obesity to see if it changes weight, heart-related risk markers, body composition, and fitness over about a year.

  Recruiting University of Kentucky · Lexington, Kentucky · NCT06967389

• Effects of CONTRAVE on weight loss and behavior in adults with obesity

  This study is testing if the weight-loss drug CONTRAVE can help adults with obesity lose weight and manage their appetite better when combined with a diet.

  Recruiting at 3 sites Phase 4 The Royal's Institute of Mental Health Research · Ottawa, Ontario and 2 other locations · NCT06809166

• Effects of a Single Workout on Gut Health in Women

  This study is testing how a single workout affects gut health and metabolism in premenopausal women of different fitness levels and body types.

  Recruiting George Washington University · Washington D.C., District of Columbia · NCT06691100

• Evaluating GS-4571 in Healthy and Obese Participants with Type 2 Diabetes

  This study is testing a new drug called GS-4571 in healthy people and those with obesity or Type 2 diabetes to see how safe it is and how the body processes it.

  Recruiting at 3 sites Phase 1 Gilead Sciences · Miami, Florida and 2 other locations · NCT06562907

• A self-management program for Chinese cancer survivors

  This study is testing a self-management program to help Chinese cancer survivors feel better, manage their weight, and improve their overall quality of life after finishing treatment.

  Recruiting at 3 sites The University of Hong Kong · Hong Kong and 6 other locations · NCT05534386

NIH-funded research (39)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• EMBER: a self-help tool to boost Veterans' use of VA weight-management programs

  A self-guided motivational tool to help Veterans learn about and join VA weight-management services.

  NIH research Veterans Admin Palo Alto Health Care Sys · Palo Alto, United States · NIH-11457418

• Weight management and center-based heart health program for Black adults with CKD

  A multi-component lifestyle program is tested to help Black adults with chronic kidney disease lower blood pressure and improve heart and kidney health.

  NIH research Duke University · Durham, United States · NIH-11453611

• GLP-1 receptor agonists before pregnancy to improve weight and pregnancy outcomes

  This project looks at whether using GLP-1 receptor agonists before pregnancy can help women with obesity lose weight and have better pregnancy outcomes.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11450921

• Hybrid implementation approach to scale a weight‑management program for adults with serious mental illness

  A Johns Hopkins team is testing how to spread and sustain a proven weight‑loss program for adults with serious mental illness in community mental health settings.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11421411

• Couples-based weight loss with a mobile app

  A couple-focused weight loss program delivered through a mobile app that helps partners support each other to lose weight together.

  NIH research University of Connecticut Storrs · Storrs-Mansfield, United States · NIH-11381762

• Addressing appetitive traits to promote weight management in children who overeat

  A family-based program is being tested to help children who overeat improve weight management by reducing food cues and increasing fullness signals.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11327220

• Teaching doctors how to talk with patients about weight and related health

  This project teaches medical residents to use short, spaced lessons and video practice over a year to improve how they talk with adult patients about weight, healthy habits, and conditions like type 2 diabetes.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11326276

• Mobile support to help young cancer survivors manage weight

  This program uses a website and app with personalized goals to help adolescent and young adult cancer survivors lose weight and be more active.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11310183

• Mental contrasting and action plans to help Veterans manage weight in primary care

  This program teaches Veterans brief mental-imagery and if-then action-planning techniques alongside the VA MOVE! program to help with weight loss and sticking to healthy habits.

  NIH research VA Medical Center · New York, United States · NIH-11308186

• Home food changes and game-like impulse-control tools to help with weight

  This project tests whether changing your home food environment and using game-like impulse-control training help adults with overweight or obesity lose more weight during a 12-month WW (Weight Watchers) program.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11293417

• Using social networks to boost weight loss for Black American women

  This project trains Black American women to share weight-loss support and information with friends and family to help themselves and people in their social circle lose weight.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-11252789

• HealthyTogether: partner and family support to help with weight loss

  HealthyTogether joins Veterans with a partner to teach communication and relationship skills to support healthier eating, activity, and weight loss.

  NIH research VA Puget Sound Healthcare System · Seattle, United States · NIH-11245700

• A tool to help Veterans engage in weight management programs

  This study is testing a helpful tool called EMBER that aims to boost motivation and involvement for Veterans in weight management programs, making it easier for them to make healthier choices and improve their overall health.

  NIH research Veterans Admin Palo Alto Health Care Sys · Palo Alto, United States · NIH-11237985

• A weight management program designed for Veterans with PTSD

  This study is testing a special weight loss program called MOVE!+UP designed for Veterans with PTSD, combining support for losing weight with helpful therapy to tackle challenges like stress and unhealthy eating, while also encouraging group activities like walks to boost both weight loss and mental well-being.

  NIH research VA Puget Sound Healthcare System · Seattle, United States · NIH-11234230

• Instagram messages and weight/health habits in young African American women

  This project looks at how Instagram images and messages like 'fitspiration', 'thinspiration', and body-positivity influence eating and exercise habits among Generation Z African American women.

  NIH research North Carolina Agri & Tech St Univ · Greensboro, United States · NIH-11172619

• Using financial incentives to help people lose weight and monitor their diets

  This study is looking at how offering rewards can help people lose weight and keep track of what they eat, using mobile apps to make it easier, so if you're trying to manage your weight, this could be a great opportunity for you!

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11099400

• Adapting a weight management program for teens with type 1 diabetes

  This study is creating a special weight management program just for teens with type 1 diabetes who are also struggling with being overweight, helping them tackle their unique challenges in a friendly and supportive way.

  NIH research Miriam Hospital · Providence, United States · NIH-11097261

• Helping children manage their weight by addressing eating behaviors

  This study is testing a new program called Regulation of Cues (ROC) to help children who have trouble with overeating learn to better manage their weight by recognizing when they're full and not reacting as much to food temptations, with support from their parents.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11095830

• Training medical residents in weight management counseling skills

  This study is all about helping doctors in training learn better ways to talk to patients about managing their weight, so they can help fight health problems like heart disease and diabetes.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11083593

• A program using digital health tools and community health workers to help public housing residents manage their weight.

  This study is testing a weight management program for people living in public housing who are dealing with obesity and related health issues, using friendly support from community health workers and helpful text messages to promote healthier eating and more exercise, while comparing their progress to a group that isn't

  NIH research Tufts Medical Center · Boston, United States · NIH-11081387

• Using digital health tools and community health workers to help residents of public housing manage their weight.

  This study is looking at how using digital health tools along with help from community health workers can support people living in public housing in Boston to manage their weight and improve their health through better eating and more physical activity.

  NIH research Tufts Medical Center · Boston, United States · NIH-11077845

• Using mobile health tools to help young cancer survivors manage their weight

  This study is testing a helpful app or website designed for young people who have survived cancer, to support them in managing their weight with personalized diet and exercise plans over six months.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11062439

• Improving weight management in Black American women through social networks

  This study is all about helping Black American women tackle obesity by using their friendships and family connections to share healthy habits and tips, so everyone can support each other in living healthier lives together.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-11028947

• Improving weight management through environmental and impulse control strategies

  This study is looking for people who are overweight or obese to try out a year-long weight management program that includes healthy eating, exercise, and mindset skills, while testing different ways to help them succeed, like changing their environment or learning to control their impulses.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11015905

• Improving weight management in adolescents by addressing weight bias

  This study is looking at how feeling bad about their weight affects teens with obesity and aims to help them manage their weight better by combining support for their feelings with healthy habits.

  NIH research Miriam Hospital · Providence, United States · NIH-11014370

• A tool to help Veterans engage in weight management programs

  This study is testing a helpful tool called EMBER that aims to boost motivation and engagement for Veterans trying to manage their weight, making it easier for them to stick with weight loss programs and improve their health.

  NIH research Veterans Admin Palo Alto Health Care Sys · Palo Alto, United States · NIH-11006238

• Using social support to help manage weight for veterans

  This study is testing a new program called HealthyTogether, which helps veterans manage their weight by encouraging support from family and friends while teaching them better communication skills, to see if this approach can lead to healthier habits and weight loss.

  NIH research VA Puget Sound Healthcare System · Seattle, United States · NIH-10996595

• Using mental strategies to help Veterans manage their weight

  This study is looking at a new way to help Veterans lose weight and get healthier by using a method called Mental Contrasting with Implementation Intentions, combined with existing programs, to make weight management easier and more effective with support from friendly educators.

  NIH research VA Medical Center · New York, United States · NIH-10929436

• Helping overweight and obese veterans manage their weight successfully

  This study is looking for veterans who are struggling with obesity and want to improve their health by trying a special weight loss program that includes a low-calorie diet and intermittent fasting, all designed to help them lose weight and feel better over 12 weeks.

  NIH research Baltimore VA Medical Center · Baltimore, United States · NIH-10919771

• Using daily self-weighing to help adolescents manage obesity

  This study is looking at how weighing yourself at home every day can help teenagers with obesity manage their weight better, by combining this practice with support from healthcare providers to encourage healthier eating and more physical activity.

  NIH research University of Minnesota · Minneapolis, United States · NIH-10917146

• Improving weight management in primary care settings

  This study is testing a new way for doctors to help patients manage their weight better by using a special tool and training, making it easier for everyone to talk about and tackle weight issues together.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-10912543

• The impact of social media messages on health behaviors in African American women

  This study looks at how social media posts with pictures can affect the eating and exercise habits of young African American women, aiming to find ways to encourage healthier lifestyles for this group that faces higher risks of obesity and related health issues.

  NIH research North Carolina Agri & Tech St Univ · Greensboro, United States · NIH-10911801

• Using financial incentives to help people lose weight and monitor their diets

  This study is looking at how different types of rewards can help people lose weight and stick to healthy eating habits, and it's for anyone who wants to manage their weight better.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-10908334

• Using financial incentives to encourage weight loss and dietary tracking

  This study is looking at how money rewards can help people lose weight and keep track of what they eat, and it's for anyone who wants to shed some pounds and stay motivated while doing it!

  NIH research Duke University · Durham, United States · NIH-10908325

• Improving pediatric weight management through telehealth

  This study is looking at how to make weight management programs for kids easier to access through online services, especially for families from different backgrounds or those with lower incomes, so that more children can get the help they need to stay healthy.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-10890018

• Helping patients maintain weight loss through technology in primary care

  This study is testing a helpful program called MAINTAIN-pc that uses your health records to give you personalized support and tools to keep off the weight you've lost, making it easier for you to maintain a healthy lifestyle with the help of your healthcare team.

  NIH research University of Utah · Salt Lake City, United States · NIH-10886020

• Improving body image support for women in weight management programs

  This study is looking at how worries about body image can impact weight loss for women, and it aims to create helpful programs that tackle these negative feelings to support healthier eating habits and better weight management.

  NIH research Miriam Hospital · Providence, United States · NIH-10832014

• Using community wellness coaching to improve weight management for underserved populations

  This study is all about helping African American adults and those from low-income backgrounds manage their weight better by bringing people together in friendly group chats led by community members, so everyone can share tips and support each other in making healthier choices.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-10825541

• Understanding why children drop out of weight management programs

  This study is looking into why many kids drop out of weight management programs and aims to find ways to keep them engaged, so families can get the support they need to help their children stay healthy.

  NIH research Wake Forest University Health Sciences · Winston-Salem, United States · NIH-10647817

Related topics

Quick answers

How many Weight Management clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 21 countries. The most sites are in United States (7 trials), Canada (2 trials), China (2 trials), Argentina (1 trial), Australia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1, Phase 1/2: 1, Phase 4: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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