Effects of a Single Workout on Gut Health in Women

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how a single session of aerobic exercise impacts the gut microbiome and metabolic activity in premenopausal women with varying fitness levels and body types. Participants will undergo a series of assessments including body composition analysis, strength and endurance tests, and will provide stool and blood samples before and after a 30-minute exercise bout. The study aims to understand the relationship between exercise and gut health by measuring changes in specific bacteria and metabolites. The findings could provide insights into personalized exercise recommendations for weight management and overall health.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Biological sex: female
* BMI 19 to 24.99 kg/m2 or BMI 30-40 kg/m2
* Exercisers: Exercise at least 4 times per week for 60 minutes (a total of 240 minutes per week) on a programmed exercise training either on endurance sports (e.g., running, cycling, triathlon), strength (e.g., powerlifting), or team sports (e.g., rugby, football, soccer)
* Non-Exercisers: Sedentary individuals who have not reached the PA guidelines (150 minutes of moderate-intensity physical activity a week, 75 minutes of vigorous-intensity physical activity, or an equivalent combination of moderate and vigorous-intensity physical activity).

Exclusion Criteria:

* Biological sex: male
* BMI \< 19 kg/m2 or \> 40 kg/m2
* Currently pregnant, \< 2 years postpartum, lactating
* Currently taking any herbal, fiber, or prebiotic supplement
* Current or 1-month before the study, taking oral or vaginal antibiotics
* Diagnosed with any gastrointestinal, endocrine, digestive, cancer, or cardiovascular disease.

Where it's running

• Milken Institute School of Public Health, The George Washington University
  Washington D.C., District of Columbia, United States Recruiting

Study contacts

• Study coordinator: Carmen Ortega-Santos, PhD, RD
• Email: carmen.ortegasantos@gwu.edu
• Phone: 2029942757

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.