NIH-funded research R01 grant

Addressing appetitive traits to promote weight management in children who overeat

Funded at University of California, San Diego · NIH-11327220 · Data updated 2026-11-12

A family-based program is being tested to help children who overeat improve weight management by reducing food cues and increasing fullness signals.

More Weight Management research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego
NIH-funded
Lab location1 site (La Jolla, United States)
Project startAugust 1, 2023
Project endMay 31, 2028
Funding year2026
Award (this year)$682,432
NIH project number5R01DK135599-04
Project IDNIH-11327220 on NIH RePORTER

Who could benefit from this research

Could help

Children with overweight/obesity who show high food cue responsiveness and their parents.

Less likely to help

Children with obesity not characterized by high food cue responsiveness or families unable to participate fully may see limited benefit.

What this research studies

This project tests the Regulation of Cues (ROC) program, a treatment designed for children with overweight or obesity and high responsiveness to food cues. It builds on Family-Based Treatment and aims to reduce overeating by teaching strategies to lower cravings and boost satiety. The study will compare ROC plus standard care to alternative approaches across multiple sites, with both children and parents involved. If successful, the program could offer a more effective, family-centered approach to weight management for kids who struggle with eating behaviors.

Why it matters

Potential benefit: If successful, families could have a more effective, evidence-based way to help children manage weight and eating behaviors.

How similar studies have gone: Earlier pilots showed ROC is feasible and promising, suggesting potential for improved outcomes in larger trials.

Where this research is happening

  • University of California, San Diego
    La Jolla, United States
    Active

Researchers

  • Principal investigator: Boutelle, Kerri N — University of California, San Diego
  • Study coordinator: Boutelle, Kerri N

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.