NIH-funded research NIH-funded research

Weight management and center-based heart health program for Black adults with CKD

Official title: Weight Management and Center-Based Cardiac Rehabilitation to Improve Health Outcomes in Chronic Kidney Disease

Funded at Duke University · NIH-11453611 · Data updated 2026-11-12

A multi-component lifestyle program is tested to help Black adults with chronic kidney disease lower blood pressure and improve heart and kidney health.

More Kidney Disease research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionDuke University
NIH-funded
Lab location1 site (Durham, United States)
Project startAugust 15, 2025
Project endJuly 31, 2030
Funding year2026
Award (this year)$778,196
NIH project number4R33HL178691-02
Project IDNIH-11453611 on NIH RePORTER

Who could benefit from this research

Could help

Adults with chronic kidney disease who are Black and have high blood pressure, willing to participate in a structured lifestyle program.

Less likely to help

Individuals without CKD, not Black, or those unable to participate in a lifestyle program may not directly benefit.

What this research studies

This study invites Black adults with CKD to participate in a structured lifestyle program that combines healthy eating, more physical activity, and weight management delivered in a clinical setting. The goal is to see if these changes can meaningfully lower blood pressure and slow kidney and heart disease progression. The program builds on prior evidence that lifestyle modifications can reduce blood pressure in the general population, and tests whether those benefits apply to people with advanced kidney disease. Participants will work with clinicians to tailor diet, activity, and weight goals while monitoring blood pressure and kidney-related markers. The grant supports a multi-year effort at Duke University to recruit enough participants to detect clinically important BP and kidney outcomes.

Why it matters

Potential benefit: If successful, the program could help Black adults with CKD achieve better blood pressure control and slower kidney and cardiovascular decline.

How similar studies have gone: Previous CKD lifestyle trials were small; this study aims to provide more definitive results in a high-risk population.

Where this research is happening

  • Duke University
    Durham, United States
    Active

Researchers

  • Principal investigator: Tyson, Crystal C — Duke University
  • Study coordinator: Tyson, Crystal C

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.