Weight management and center-based heart health program for Black adults with CKD
Official title: Weight Management and Center-Based Cardiac Rehabilitation to Improve Health Outcomes in Chronic Kidney Disease
Funded at Duke University · NIH-11453611 · Data updated 2026-11-12
A multi-component lifestyle program is tested to help Black adults with chronic kidney disease lower blood pressure and improve heart and kidney health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | August 15, 2025 |
| Project end | July 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $778,196 |
| NIH project number | 4R33HL178691-02 |
| Project ID | NIH-11453611 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with chronic kidney disease who are Black and have high blood pressure, willing to participate in a structured lifestyle program.
✕Less likely to help
Individuals without CKD, not Black, or those unable to participate in a lifestyle program may not directly benefit.
What this research studies
This study invites Black adults with CKD to participate in a structured lifestyle program that combines healthy eating, more physical activity, and weight management delivered in a clinical setting. The goal is to see if these changes can meaningfully lower blood pressure and slow kidney and heart disease progression. The program builds on prior evidence that lifestyle modifications can reduce blood pressure in the general population, and tests whether those benefits apply to people with advanced kidney disease. Participants will work with clinicians to tailor diet, activity, and weight goals while monitoring blood pressure and kidney-related markers. The grant supports a multi-year effort at Duke University to recruit enough participants to detect clinically important BP and kidney outcomes.
Why it matters
Potential benefit: If successful, the program could help Black adults with CKD achieve better blood pressure control and slower kidney and cardiovascular decline.
How similar studies have gone: Previous CKD lifestyle trials were small; this study aims to provide more definitive results in a high-risk population.
Where this research is happening
-
Duke University
Durham, United States Active
Researchers
- Principal investigator: Tyson, Crystal C — Duke University
- Study coordinator: Tyson, Crystal C
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.